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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2005When to draw blood for PSA?
Are PSA readings affected by the timing of the digital exam. That is, will level of the PSA reading vary with when (either before or after blood is drawn) the digital exam is given? If you have references, I'd appreciae it. Thanks.  SignatureTo email, erase "forgetit" > Are PSA readings affected by the timing of the digital exam. That is, > will level of the PSA reading vary with when (either before or after > blood is drawn) the digital exam is given? If you have references, I'd > appreciae it. Thanks. According to patrick Walsh in "Guide to Surviving Prostate Cancer", many things can affect the PSA reading. These include sex, DRE, and several other things. It is best to wait a few days after a DRE before giving the blood sample. > Are PSA readings affected by the timing of the digital exam. That is, > will level of the PSA reading vary with when (either before or after > blood is drawn) the digital exam is given? If you have references, I'd > appreciae it. Thanks. There has been a paper published about this, but I don't have the reference handy. Basically, 30 minutes after a DRE, the PSA goes up an average of 0.4. Ed Friedman >> Are PSA readings affected by the timing of the digital exam. That >> is, will level of the PSA reading vary with when (either before or [quoted text clipped - 6 lines] > > Ed Friedman When my urologist gave me a DRE and then shortly thereafter he drew blood for a PSA, I asked him about the accuracy of the PSA under this condition. He said it didn't matter which was done first. So, an average of 0.4 bump in PSA seems to go along with his reply as this doesn't seem to be too significant a change. SignatureTo email, erase "forgetit" Flycaster wrote...snip... > When my urologist gave me a DRE and then shortly thereafter he drew > blood for a PSA, I asked him about the accuracy of the PSA under this > condition. He said it didn't matter which was done first. So, an > average of 0.4 bump in PSA seems to go along with his reply as this > doesn't seem to be too significant a change. There are a number of studies on the effect of DRE prior to blood draw upon PSA level (you can find them on PubMed). Increases larger than 0.4 ng/ml are typically observed. These studies have led the medical community to adopt a post-blood draw DRE procedure. Aside from confusing the individual reading, prostate manipulation prior to blood draw will also confuse the trend in the PSA over time. An increase this time, no increase next time, will make it harder to discern the trend and delay diagnosis and confuse prognosis...Best wishes and good health, Ron |
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