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Medical Forum / Diseases and Disorders / Prostate BPH / March 2005

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Biopsy Results Question

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Tom Lawrance - 25 Feb 2005 19:00 GMT
My last DRE revealed a "grainy" pea-sized, nodule on my prostate and
a PSA >1    . So my urologist suggested I have a biopsy which,
thankfully, revealed no tumor in any of the 16 samples taken.

I was, however, surprised to find that the pathology report failed to
characterize the samples as anything other than "No tumor present,"
considering that a pathologist  evidently had  to examine the samples
microscopically, and this failure still leaves my urologist and I
wondering what the abnormal area is.

Since the hospital I went to is a well-respected, teaching hospital, I
was wondering if the failure to characterize prostate tissue as other
than tumorous or non-tumerous is standard procedure elsewhere in the
country. In addition, I was wondering what the chances are that  this
tissue, as opposed to normal tissue, will become cancerous, since my
urologist told me that if a follow-up PSA in 6 months showed a rise,
he'd want to do another biopsy.

Thanks very much in advance for the info.

BTW, the biopsy was completely painless, because it was done in the
hospital under mild anaesthesia, and I was out and normal in a few
hours . So I'd highly recommend that it be done this way.
Stephen Jordan - 25 Feb 2005 19:22 GMT
On February 25, Tom Lawrance wrote, in pertinent part:

> I was, however, surprised to find that the pathology report failed to
> characterize the samples as anything other than "No tumor present,"
[quoted text clipped - 9 lines]
> urologist told me that if a follow-up PSA in 6 months showed a rise,
> he'd want to do another biopsy.

Seems surprising to me, too.

No mention of prostatic intra-epithelial neoplasia (PIN)? Nor of
inflammation?

PIN is thought to be a precursor of PCa. Inflammation could be from,
e.g., infection. The uro might prescribe a medication such as Cipro for
that. But OTOH, inflammation should raise PSA and <1 makes it seem unlikely.

I recommend that the slides and paraffin block be sent to one of the
well-respected labs that specialize in prostate biopsy studies. They can
be found listed on the website of Prostate Cancer Research Institute at
http://prostate-cancer.org/index.html

The uro should also have such info.

My second opinion was done by Bostwick in Virginia. Cost = $340.
Insurance covered. I found it to be very much more informative than the
report from the local path lab.

I would not let this lie. I'd want to know not only what it isn't but
what it *is.*

(snip)

> BTW, the biopsy was completely painless, because it was done in the
> hospital under mild anaesthesia, and I was out and normal in a few
> hours . So I'd highly recommend that it be done this way.

Me, too. Only way to fly.

Regards,

Steve J
Ron - 25 Feb 2005 23:26 GMT
Attention Posters:
There is a "cancer" newsgroup and a "BPH" newsgroup. Please don't confuse
them when you decide where to post. There is a reason that they're separate.
Thanks,
Ron

> From: Stephen Jordan <mycroftscj@earthlink.net>
> Organization: EarthLink Inc. -- http://www.EarthLink.net
[quoted text clipped - 53 lines]
>
> Steve J
Stephen Jordan - 25 Feb 2005 23:36 GMT
On February 25, the top-posting Ron wrote, quoting me:

> Attention Posters:
> There is a "cancer" newsgroup and a "BPH" newsgroup. Please don't confuse
> them when you decide where to post. There is a reason that they're separate.
> Thanks,
> Ron

Attention Ron:

Tom crossposted to both groups, so I chose to respond in the same
manner. I do know how to manage my newsgroup postings, thank you.

Regards,

Steve J

PS: Top-posting is contrary to Usenet protocol.
Ron - 26 Feb 2005 00:03 GMT
An expert on so called "protocol" who can't post to the proper group!

> From: Stephen Jordan <mycroftscj@earthlink.net>
> Organization: EarthLink Inc. -- http://www.EarthLink.net
[quoted text clipped - 21 lines]
>
> PS: Top-posting is contrary to Usenet protocol.
daddyo - 28 Feb 2005 00:48 GMT
Hello,

What is top-posting ? Is there an official Usenet protocol and if so
do you have a link to it ?

Thanks
Richie

>On February 25, the top-posting Ron wrote, quoting me:
> >
[quoted text clipped - 14 lines]
>
>PS: Top-posting is contrary to Usenet protocol.
Stephen Jordan - 28 Feb 2005 01:20 GMT
On February 27, daddyo inquired:

> What is top-posting ? Is there an official Usenet protocol and if so
> do you have a link to it ?

Top posting, aka in-line posting, is covered here:

http://www.river.com/users/share/etiquette/

Unfortunately, all too many people revel in their ignorance and lack of
regard for others. They seem proud of their boorishness.

Regards,

Steve J
daddyo - 01 Mar 2005 03:22 GMT
Hello Steve,

Sorry to top post again,but I read the etiquette page and whilst
agreeing with their guidelines on every thing else,I'm not so sure
about top posting.

The fact is that nearly everyone does it ,and in 8 years of usenet I
have never seen any complaint about the practice.
I can't see that it causes any problems in this group but I can see
how in a long and involved discussion in a more technical group,top
posting could cause problems.

Anyway ,I am glad I know now,and not intending to start a dispute,I
would be interested in other views on the matter. The section on
"judicious quoting " is definitely valid and probably the use of top
posting is to overcome the need to scroll down reams of repeated text.

The bottom line is that it requires a more disciplined approach to
posting and it is unrealistic to expect all casual users to bother
with the finer points. I personally will try to follow the guidelines
from now on. (hey ! don't hold me to that....)

regards Richie

>On February 27, daddyo inquired:
>>
[quoted text clipped - 11 lines]
>
>Steve J
Mike - 01 Mar 2005 13:02 GMT
Exactly why top posting is a good idea.  Rule:

If you have one point to make then top post.

If you have several points to make then intersperse your comments with
quotes from the other poster, suitably [snip]ped.

> Hello Steve,
>
[quoted text clipped - 35 lines]
>>
>>Steve J
Gut-Buster - 01 Mar 2005 20:23 GMT
PLEASE - can we stop this "TOP POST Vs BOTTOM POST" stuff? It's ALL crap.
However a person chooses to post, no-one can change it and there is no
"rule" as to how you HAVE to post. If a rule were to be enforced then we
couldn't actually do the style of posting that the program disallows.

Just live with it. We have much more serious issues in here.

> Exactly why top posting is a good idea.  Rule:
>
[quoted text clipped - 40 lines]
>>>
>>>Steve J
Ron - 28 Feb 2005 01:26 GMT
You just did it, you naughty boy. Hey  - me too.
Oh well.

> From: rgh@opera.com (daddyo)
> Reply-To: rgh@opera.com
[quoted text clipped - 28 lines]
>>
>> PS: Top-posting is contrary to Usenet protocol.
amaze - 26 Feb 2005 11:13 GMT
Perhaps you are unaware of the fact that more than 1 in 10 of prostate
problems which are initially diagnosed as being BPH are eventually
proved to be cancer.

>Attention Posters:
>There is a "cancer" newsgroup and a "BPH" newsgroup. Please don't confuse
>them when you decide where to post. There is a reason that they're separate.
>Thanks,
>Ron
Ron - 26 Feb 2005 16:23 GMT
Yes. and that's why it is free and easy to check out both wonderful
newsgroups.

> From: amaze <B@B.B>
> Organization: BT Openworld
[quoted text clipped - 11 lines]
>> Thanks,
>> Ron
 
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