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Medical Forum / Diseases and Disorders / Prostate BPH / February 2005

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Michael Balarama - 08 Feb 2005 18:10 GMT
Was on the news-the Dr has this little health tip
she siad the combination of  doxazosin and finasteride shank the prostate...
here is the study.
Michael
BPH treatment

Mike Perine has BPH, benign prostatic hyperplasia, more commonly known as an
enlarged prostate. He participated in a major clinical trial to see if
medication could help him escape surgery.

"I was trying to avoid any, any complications to get it to that extent.",
said Perine.

Doctor Joe Ramsdell says, "Surgery used to be the standard of treatment.
over the last ten years, a number of medications have been developed."

Researchers tested two of them - doxazosin and finasteride. They found that
each of the drugs slow down the progression of BPH and reduce the need for
surgery. In combination, they are safe and doubly effective.

"Each of them reduced it by probably a third. I mean that's a big change.
but when you put them together, reduction was by two-thirds.", says Dr.
Ramsdell.

The prostate gland sits under the bladder and surrounds the urinary canal.
As it grows it chokes off the flow of urine. Doxazosin, an alpha blocker,
relaxes the prostate to improve the flow. Finasteride inhibits testosterone
production and shrinks the prostate.

Ramsdell says, "As a result of that trial, medical management probably has
now become the new standard treatment for, for bph in men who have
symptoms."

And more good news. Men with mild symptoms may get by with watchful
waiting - where the only treatment is a doctor's watchful eye on the
condition. Because of his mild symptoms, it was Perine's treatment of
choice.
http://www.4-men.org/benign-prostate-hypertrophy/doxazosin-and-finasteride.html
Michael Balarama - 08 Feb 2005 18:12 GMT
Long-term combination therapy with doxazosin and finasteride was safe and
reduced the risk of overall clinical progression of benign prostatic
hyperplasia significantly more than did treatment with either drug alone.
Combination therapy and finasteride alone reduced the long-term risk of
acute urinary retention and the need for invasive therapy. Copyright 2003
Massachusetts Medical Society

> Was on the news-the Dr has this little health tip
> she siad the combination of  doxazosin and finasteride shank the prostate...
[quoted text clipped - 33 lines]
> condition. Because of his mild symptoms, it was Perine's treatment of
> choice.

http://www.4-men.org/benign-prostate-hypertrophy/doxazosin-and-finasteride.html
 
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