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Medical Forum / Diseases and Disorders / Prostate BPH / January 2005

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PSA test

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Michael Balarama - 21 Sep 2004 19:50 GMT
went to my urologist today for the yearly check-asked about the PSA test and
what I read about it being not so good-he said for guys my age 55-true but
for older guys it can save their life-he says it has pointed to cancer in
some of his patients that they never would have discovered(and saved their
lives)..he said at my age-he looks at the PSA number over a few years to see
if it spiked-it has been about 2.5 for 4 years..
He said my prostate has been the same size for 4 years. 35 grams...
Michael
Gutbuster - 21 Sep 2004 22:11 GMT
> went to my urologist today for the yearly check-asked about the PSA test
> and
> what I read about it being not so good-he said for guys my age 55-true but
> for older guys it can save their life-he says it has pointed to cancer in

I honestly dont know how he can make such a stupid comment. The test either
works or it doesnt and the latest data says it doesnt. So why would the test
care what age a person is?

The fact that a person who went through a PSA was found to have cancer
because he went for that test, according to what I have read, is because
blind Freddy could have found it with a white cane.
Michael Balarama - 22 Sep 2004 01:28 GMT
> > went to my urologist today for the yearly check-asked about the PSA test
> > and
[quoted text clipped - 8 lines]
> because he went for that test, according to what I have read, is because
> blind Freddy could have found it with a white cane.

He said the high PSA reading-the jump from his last test numbers-alerted
them to cancer..
Gutbuster - 22 Sep 2004 13:54 GMT
>> > went to my urologist today for the yearly check-asked about the PSA
>> > test
[quoted text clipped - 16 lines]
> He said the high PSA reading-the jump from his last test numbers-alerted
> them to cancer..

....which in no way invalidates what I posted.
Jack - 22 Sep 2004 01:42 GMT
> > went to my urologist today for the yearly check-asked about the PSA test
> > and
[quoted text clipped - 8 lines]
> because he went for that test, according to what I have read, is because
> blind Freddy could have found it with a white cane.

The test is still valid, not only for tracking the size of the prostate,
which also be done by a DRE, but for giving an indication of the possibility
of cancer by a sudden rise in the psa value.  Also a DRE will not detect the
medial lobe growth into the bladder.  There is no question that as the
prostate grows so does the psa value, but the rise is gradual in bph.  A
sudden jump in the value, of 50% or more is sufficient to cause concern,
cancer being one, prostatitis is another.

Age does play a role, since bph normally has its onset in males over 50.
However, there are a number of males who have bph in their 40's.  I would
suggest that anyone with bph should have a psa test done anually.  If the
rise in the psa values is very gradual, then the indication is that the
prostate is growing normally with age.  Any sudden jump should be further
examined, by biopsy, or at least milking the prostate to see if there are
any abnormal fuilds in the prostate, which might indicate prostatitis.  If
prostatitis is ruled out then a biopsy should be done.

Jack
Gutbuster - 22 Sep 2004 14:00 GMT
>> > went to my urologist today for the yearly check-asked about the PSA
>> > test
[quoted text clipped - 20 lines]
> the
> medial lobe growth into the bladder.

Apparently, no to the cancer bit. It is being reported as being no more
reliable than pointing a bone at you and seeing if it wobbles to prove you
have cancer.

There is no question that as the
> prostate grows so does the psa value, but the rise is gradual in bph.  A
> sudden jump in the value, of 50% or more is sufficient to cause concern,
> cancer being one, prostatitis is another.

I have a friend also with prostate problems. The guy has had BLADDER cancer
(they stick something up your dick and scoop out layers of the bladder from
the inside until there is no cancer) and lung cancer. Each time the cancer
was found, it was beaten thank goodness. His prostate got so bad he was up
pissing maybe 6 or 7 times a night. He was constantly under "cancer watch"
and at no time, as his prostate got larger and larger, did he ever even LOOK
like he was getting cancer. So, as to your statement that as the bladder
grows etc, it depends on each person.

> Age does play a role, since bph normally has its onset in males over 50.
> However, there are a number of males who have bph in their 40's.  I would

I have had prostatitis at the very least since my middle 30s. I am 49 now
and a large prostate. No cancer though I peed blood and also had it all
bloody after sex (coming from me) a few weeks back. I am not concerned that
the peeing blood means I have cancer. I have had a sporting accident when I
was a kid that ruptured a kidney. It was bound to start playing up sooner or
later.
Jack - 22 Sep 2004 19:48 GMT
> > The test is still valid, not only for tracking the size of the prostate,
> > which also be done by a DRE, but for giving an indication of the
[quoted text clipped - 6 lines]
> reliable than pointing a bone at you and seeing if it wobbles to prove you
> have cancer

If you have a psa value of 10 after having a value of 5 the year before,
there is a 50/50 chance you have prostate cancer.  The question is how
aggressive is the cancer.  A biopsy will give you that answer.

>  There is no question that as the
> > prostate grows so does the psa value, but the rise is gradual in bph.  A
[quoted text clipped - 9 lines]
> like he was getting cancer. So, as to your statement that as the bladder
> grows etc, it depends on each person.

I said as the prostate grows, not the bladder.  Although I did mention that
the medial lobe of the prostate can grow into the neck of the bladder.

> > Age does play a role, since bph normally has its onset in males over 50.
> > However, there are a number of males who have bph in their 40's.  I would
>
> I have had prostatitis at the very least since my middle 30s.

Prostatitis and bph are two entirely different conditions.  Prostatits is
inflamination of the prostate caused by an infection.  BPH is caused by the
benign growth of the tissue of the prostate,  believed to be caused by
excess dihydroxi-testosterone in the system.

I am 49 now
> and a large prostate. No cancer though I peed blood and also had it all
> bloody after sex (coming from me) a few weeks back. I am not concerned that
> the peeing blood means I have cancer. I have had a sporting accident when I
> was a kid that ruptured a kidney. It was bound to start playing up sooner or
> later.

I would have that checked out.  As you said it may be caused by the ruptured
kidney, which should have been removed, if the rupture was servere enough to
cause the kidney to quit functioning.  The only cases of blood coming from
the prostate that I know of is when the prostate has been cut.  By a biopsy
or any resection of the prostate, such as TURP, PVP, TUNA, TUMT or what have
you..  However, if you had blood in your ejaculate during intercourse,
without having had any of the above mentioned within three weeks of the
sexual activity, I would see a urologist
MB - 23 Sep 2004 19:18 GMT
Jack:

Actually, your comments are not quite correct. Blood in the semen is almost
always (yes, there are exceptions) a very benign matter. I remember reading
articles that said things like blood in the urine needs to be absolutely
checked out. Ditto for blood in the stool or blood in the vomitus. However,
blood in the semen is not a problem.

Anyway, I read up on this because I suddenly started getting blood in the
semen. My doctor was not too alarmed. However, it didn't go away quickly so
he sent me to a urologist (one who is well-respected and has practiced for
many years). He kind of chuckled and said: [paraphrasing]:  "Look, it is no
problem; it never is. You broke a blood vessel. The prostate is loaded with
many small blood vessels. You probably bled once or twice. But the blood
stays in the prostate and slowly gets expelled via ejaculations." In fact,
my semen started as blood red (which quickly led me to my first doctor
visit). As time went on the color turned lighter/rusty. As the urologist
predicted, it went away. He said it could actually take 25 or so
ejaculations before it is gone. But it was probably a single bleed.

I'm glad the urologist didn't make a big thing out of it!

Mel

>> > The test is still valid, not only for tracking the size of the
>> > prostate,
[quoted text clipped - 75 lines]
> without having had any of the above mentioned within three weeks of the
> sexual activity, I would see a urologist
Jack - 23 Sep 2004 21:37 GMT
Mel,

Thanks for the info.  Good to know if it ever happens to me, although now
that I have retro, the doc will have to figure it out.  If it only happens
after an ejaculation, I guess I can assume it came from the prostate
Thanks again.

Jack
> Jack:
>
[quoted text clipped - 19 lines]
>
> Mel
Gutbuster - 23 Sep 2004 22:30 GMT
> Jack:
>
[quoted text clipped - 3 lines]
> absolutely checked out. Ditto for blood in the stool or blood in the
> vomitus. However, blood in the semen is not a problem.

I regularly have bloody stools and twice have had bloody semen in about 18
months. Neither are things to worry about for me and most people. Bloody
stools can just mean that, like me, you suffer from bad gastric reflux and
acid and that it has made things difficult and you bleed a lot in the bowels
when going to the toilet and nothing else. Eg, there is no cancer or
anything else, just skin that bursts somewhere in your bowels, bleeds for a
time and heals over until the next time.
MB - 24 Sep 2004 05:24 GMT
Uh... Gut:

I trust you had a colonoscopy to rule out any serious problem???

Bleeding in the bowels is MUCH more worrisome until proven otherwise.

Usually, if you can see it as red blood, it is due to very benign causes
(hemorr., fissures, etc.). I guess the black tarry bleeds are from higher up
and a bit more of concern. But that should STILL be checked out (I've been
there, too!).

Mel

>> Jack:
>>
[quoted text clipped - 11 lines]
> or anything else, just skin that bursts somewhere in your bowels, bleeds
> for a time and heals over until the next time.
Robert A. Fink, M. D. - 25 Sep 2004 22:09 GMT
>Uh... Gut:
>
[quoted text clipped - 8 lines]
>
>Mel

This is very true.  Bloody stools are potentially the sign of
something serious.

Best,

Bob

Robert A. Fink, M. D.
Neurological Surgery
2500 Milvia Street  Suite 222
Berkeley, CA  94704-2636  USA
510-849-2555

**********************************
NOTE:  The material above is not "medical
advice".  Medical advice can only be
given after an in-person contact between
doctor and patient.
**********************************
Gutbuster - 26 Sep 2004 14:58 GMT
>>Uh... Gut:
>>
[quoted text clipped - 12 lines]
> This is very true.  Bloody stools are potentially the sign of
> something serious.

Worse than that, going to the doctor over here is a sign that you are a
hypochondriac. If you don't go to the doctor, you aren't one.
MB - 26 Sep 2004 23:16 GMT
Gut:

Your response makes no sense.
Going to the doctor with blood in the stools would NEVER be the sign of a
hypochondriac.

Not going would be a sign of stupidity.

Mel

>>>Uh... Gut:
>>>
[quoted text clipped - 16 lines]
> Worse than that, going to the doctor over here is a sign that you are a
> hypochondriac. If you don't go to the doctor, you aren't one.
Gutbuster - 27 Sep 2004 14:06 GMT
> Gut:
>
> Your response makes no sense.
> Going to the doctor with blood in the stools would NEVER be the sign of a
> hypochondriac.

Are you an American? I dont mean that in any possible nasty way. I am just
saying you dont understand the doctors here. You are a hypochondriac for
going to a doctor over here, according to most doctors, unless something
definitely turns up but in most cases, it only turns up because you land in
hospital.

> Not going would be a sign of stupidity.

Actually the other way around. If you go, you get treated like a bludger and
a hypochondriac but if you end up carted to hospital and get admitted on the
spot then you will be treated like a patient. By the time that happens
though....
MB - 27 Sep 2004 17:09 GMT
Gut:

Somehow, I doubt that. (Yes, I am an American).

Suppose you went to the doctor with a suspicious mole. They biopsy or remove
it and it turns out to be benign. Do you mean you would be considered stupid
for having it looked at??

That makes no sense to me.

Mel

>> Gut:
>>
[quoted text clipped - 14 lines]
> on the spot then you will be treated like a patient. By the time that
> happens though....
Gutbuster - 26 Sep 2004 14:57 GMT
> Uh... Gut:
>
> I trust you had a colonoscopy to rule out any serious problem???

Yep, back in Feb 1990.

> Bleeding in the bowels is MUCH more worrisome until proven otherwise.

Depends on what the problem is causing it. Mine was caused by too much acid
basically stripping skin away to the point that when having a sh.t, I bleed.
Simple as that.

> Usually, if you can see it as red blood, it is due to very benign causes
> (hemorr., fissures, etc.). I guess the black tarry bleeds are from higher
> up and a bit more of concern. But that should STILL be checked out (I've
> been there, too!).

I get both all the time. Have been since the middle 80s. Still here.
MB - 26 Sep 2004 23:14 GMT
Gut:

What you said just underscores my point:

Bleeding in the bowels is MUCH more worrisome until proven otherwise

I'm glad yours was proved otherwise!!!

Mel

>> Uh... Gut:
>>
[quoted text clipped - 14 lines]
>
> I get both all the time. Have been since the middle 80s. Still here.
MB - 26 Sep 2004 23:19 GMT
Gut:

I don't know your age, but after 14 years you might be due for another
colonosc. just as a routine screening procedure.

Especially in your case, where you do consistently have bleeding, you would
not recognize new bleeding due to cancer.

Mel

>> Uh... Gut:
>>
[quoted text clipped - 14 lines]
>
> I get both all the time. Have been since the middle 80s. Still here.
Gutbuster - 27 Sep 2004 14:11 GMT
> Gut:
>
[quoted text clipped - 3 lines]
> Especially in your case, where you do consistently have bleeding, you
> would not recognize new bleeding due to cancer.

You wont be diagnosed with having bowel cancer here until you are so far
gone you are just about dead. Case in point - a customer of mine told me he
was selling his business due to bowel cancer and having 3 months to live but
undergoing chemo and if it worked, maybe 18 months. He had been sick and
badly off for about 3 years. Each time he went he was told it was all in his
head. So, he goes to the hospital with gut pains that wont go away. He was
admitted, tested and found to have inoperable bowel cancer and asked why he
didn't get it looked into years ago when it wouldn't have been inoperable.
He said to me "I just looked at them with my mouth hanging open and told
them, eventually, that I had been many times. They didn't have anything to
say after that". I told him to sue the doctor but he said he was told he
would have 3 months and now that he is undergoing chemo, he is too weak.

That's life over here.
MB - 27 Sep 2004 17:10 GMT
Gut:

Where is "over here."

Where are you located?

(Also, if what you say is even remotely correct, remind me never to move
there!)

Mel

>> Gut:
>>
[quoted text clipped - 19 lines]
>
> That's life over here.
Spread deMocracy - 02 Oct 2004 10:28 GMT
I believe 4 or greater is the number that starts ringing bells of concern.
Some doctors use a bit lower number.   It is a potential screening tool, not
a direct indicator.  2.5 sounds good, (in my non-medical opinion).    2.5
plus digital examine  and if digital does not locate any cysts, then likely
the doctor considers you to be OK.  And that does make sense, in my
non-medical opinion.   Best of luck to you.

"Michael Balarama" <mbalar@ev1.net> wrote in message  PSA number over a few
years to see
> if it spiked-it has been about 2.5 for 4 years..
> He said my prostate has been the same size for 4 years. 35 grams...
> Michael
drberry - 26 Jan 2005 02:16 GMT
Michael, most of the data suggest that there is a relationship between
age and PSA level. The older one gets, the higher it goes.
Seems to be related to increase in prostate size (BPH) as one grows
older.The PSA now appears to be strongly related
to the degree of inflammation in the prostate. More recent research
indicates that it may not be
a good marker for cancer in a large majority of males, especially
those over 50.
It is sad that many practitioners don't keep up-to-date on the research.
> went to my urologist today for the yearly check-asked about the PSA test and
> what I read about it being not so good-he said for guys my age 55-true but
[quoted text clipped - 4 lines]
> He said my prostate has been the same size for 4 years. 35 grams...
> Michael
c palmer - 26 Jan 2005 07:42 GMT
i wanted to address both of the posts because they are related. please
seee comments between.

~ curtis
=========

Re: prostate cancer biopsy  

From: drberry@cox.net (drberry)
Most biopsies are not pleasant and the morbidity rate is somewhat
high....post bleeding, prostatitis,
and pain. One practitioner told me that he had a patient with PSAs in
the 20's;
he had multiple
biopsies, and no cancer was discovered. For a while so-called "doubling
time" was considered
important, but now most researchers are warning that the PSA is not an
accurate measure to diagnose
cancer.
In any event, about 10% of prostate cancer patients die soon regardless
of any treatment (life can be prolonged some months though...but the
quality of life may be low). Most, around 90%, who have
cancer cells in their prostates live a normal life span and die with
cancer, not from cancer. I have a
colleague/friend, who was diagnosed a decade ago with PC (with a high
Gleason score) who decided to do watchful waiting, and he is still alive
with no problems (except for a high PSA). I, myself, have always run a
PSA varying between 5 and 7, and plan to do nothing -- other than
not measuring the PSA anymore.
Michael Balarama wrote:
What is a prostate cancer biopsy..They want to do one on me because my
PSA was elevated..Dr said it is unpleasant and they go in through the
but. PSA was 3.4 up from 2.5 the last 5 years.
Michael  
Re: PSA test  
===============> the PSA test is a very strong test if used as for what
it is intended for.  most people only understand part of what the PSA
test does and that is MEASURE psa in the blood stream.  they don't
understand the purpose of those numbers.

yes, prostate infections can drive psa up fast and quickly.  but knowing
how the psa level and prostate work can make the difference between life
and death of the individual.  if you have a psa velocity rise of .75 in
one year, that should trigger a need for a biopsy.  this is after a
round of antibiotics is given and confirmed that the psa rise is valid.
a .75 indicates that it COULD be an aggressive prostate cancer.  sure,
there may be some negative biopsies, but for the ones that the prostate
cancer was detected, it just saved their life.

the comment PSA was 3.4 up from 2.5 the last 5 years is not a fast
velocity rise, but it is indicating that something is going inside the
body and medical staffs are using the 4.0 as an absolute cutoff number.  

it is a fact that 15 to 20% of the men at age 50 have prostate cancer
inside the prostate.  they don't know why some pca will take off while
others, the pca doesn't develop, but if the person was to die and they
opened his prostate up, he would have pca cells inside the prostate.
so, what causes pca to go active - i don't know.  the only tool that can
detect this change is the psa test.

now to the next post........

From: drberry@cox.net (drberry)
Michael, most of the data suggest that there is a relationship between
age and PSA level. The older one gets, the higher it goes. Seems to be
related to increase in prostate size (BPH) as one grows older.The PSA
now appears to be strongly related to the degree of inflammation in the
prostate. More recent research indicates that it may not be
a good marker for cancer in a large majority of males, especially those
over 50.
It is sad that many practitioners don't keep up-to-date on the research.
Michael Balarama wrote:
went to my urologist today for the yearly check-asked about the PSA test
and what I read about it being not so good-he said for guys my age
55-true but for older guys it can save their life-he says it has pointed
to cancer in some of his patients that they never would have
discovered(and saved their lives)..he said at my age-he looks at the PSA
number over a few years to see if it spiked-it has been about 2.5 for 4
years.. He said my prostate has been the same size for 4 years. 35
grams... Michael
===========> first, a biopsy is mildly uncomfortable, but they are not
painful.  they can use a numbing agent before hand or in my case, they
didn't.  most people don't want something the size of a small broom
handle stuck up them and that is the uncomfortable part is, but it
certainly not miserable.  it is an ultra-sound device that shows the
doctor where the areas of prostate cancer may be.  the biopsy is the
gold standard as far as knowing if you have prostate cancer or not.  the
worse pain i had was when they fired the needles and it felt like having
a rubber band on your wrist and snapping it lightly.  that was it.

as far as the morbidity rate is somewhat high....post bleeding,
prostatitis,  - nothing is further from the truth.  it is VERY RARE  if
someone was to die from a biopsy.  yes, there is some post bleeding, but
it goes away as the prostate heals, and the biopsy does not caused
prostatitis.

the comment - I have a
colleague/friend, who was diagnosed a decade ago with PC (with a high
Gleason score) who decided to do watchful waiting, and he is still alive
with no problems (except for a high PSA). I, myself, have always run a
PSA varying between 5 and 7, and plan to do nothing -- other than
not measuring the PSA anymore.

============> reminded me of a person who used alt. meds to treat his
pca.  he refused the conventional treatments.  he did keep his psa
around 300 to 400 and was going in to see the doctor in that november.
i died within a few weeks after that.

here's the cold hard facts.  it takes approx. 8 years from prostate
cancer to develop and spread into the body.  it takes approx 5 years
from that point before the pca spreads into one of the vital organs for
life and the person dies, so you are looking at an approx. 13 year
window depending on what a person's gleason score is.

so the person who has pca for 10 years and done watchful waiting is
still alive except for the high psa,  can you guess how much longer he
has?   and the high psa number?  this is the amount of hormone that is
available to feed the prostate cancer, so it will develop even faster
and shorten up his doubling rate.  

what i did not cover is that how pca spreads - it usually goes into the
nearby bones - the lower back and hips.  the bones gets very thin and
collapse which accounts for the  pain.  it is a pain like you can not
imagine and there are three different level management level in the
final stages of life.  i should know.  i have walked this path to the
very end with my own father who did the watchful waiting and i was dx'ed
30 years before the age he developed it.  so it has affected my life
too.

as to the comment - I, myself, have always run a PSA varying between 5
and 7, and plan to do nothing -- other than
not measuring the PSA anymore.
========> i will say "good luck" and wish no harm and a very good life
for what lies ahead.
-------------

i posted this because i want to put out the correct information on the
psa test.  it is what saved my life and triggered the biopsy, which
showed i have prostate cancer in BOTH lobes.  i was only 56 at that
time.

~ curtis

knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
http://community.webtv.net/PALMER_ENT/doc
 
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