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Medical Forum / Diseases and Disorders / Prostate BPH / July 2004

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Thanks, Lee!

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Rob Marks - 11 Jul 2004 18:37 GMT
First, thanks Lee for coordinating this poll.  It's most helpful
because no peer-reviewed journal or publication has yet published on
the efficacy of PVP.

Secondly, for the umpteenth time (that I've posted these here) let me
reiterate that U.S. Government statistics are and have been available
on TURP, a procedure which has been around for at least 30 years.  A
free booklet issued by the National Institutes of Health in
Washington, D.C., several years ago reported that the chances of
impotence following a TURP were one in five; that the likelihood of
permanent incontinence was 1 in 20 and that the risk of mortality was
1 in 250.

Given these numbers, why would anyone nowadays want to consider TURP?

To date, I haven't seen a message on this board that reports anyone
dying after PVP or anyone reporting incontinence or impotence.  The
worst scenarios seem to be retrograde ejaculation and increased
urinary frequency.

I, myself, am still waiting for some improvements in PVP, as my
situation is not critical.  However, if I should someday find myself
blocked, I would submit to a PVP procedure in a moment.
riserman@optonline.net - 12 Jul 2004 15:16 GMT
Rob,

Something about those numbers you report sounds wrong. I cannot imagine
that hundreds if not thousands of Urologists have been performing TURP's
that are leaving 20% of their patients permanently impotent or causing 1
in 250 to be incontinent for the rest of their lives.

What is the exact name, source and publication date of the "booklet" you
refer to, and how old is the data used to support its conclusions.

Thanks,

Bob


> First, thanks Lee for coordinating this poll.  It's most helpful
> because no peer-reviewed journal or publication has yet published on
[quoted text clipped - 19 lines]
> situation is not critical.  However, if I should someday find myself
> blocked, I would submit to a PVP procedure in a moment.
nambucca - 12 Jul 2004 23:35 GMT
> Rob,
>
[quoted text clipped - 33 lines]
> > situation is not critical.  However, if I should someday find myself
> > blocked, I would submit to a PVP procedure in a moment.

They are the exact same figures any decent uro in the UK will give you if
they are pressed for the info plus they will tell you that retro is a high %
too if a TURP is done
riserman@optonline.net - 13 Jul 2004 00:38 GMT
First, you didn't answer my question. Second, I don't believe these
numbers because they defy credibility. Twenty percent permanent
impotency from a TURP makes no sense since the nerves that control an
erection are on the outside of the prostate nowhere near the area
operated on either by a TURP or PVC. By the way, I recently had a TURP
and am not impotent or incontinent.

Bob

> > Rob,
> >
[quoted text clipped - 37 lines]
> they are pressed for the info plus they will tell you that retro is a high %
> too if a TURP is done
Burr - 13 Jul 2004 02:56 GMT
I found this on Medline. It shows 15.6 percent.

I did quite a bit of web searching and the numbers, as bad as they seem,
appear to be correct.

Burr

[Reevaluation of impotence following TURP]

[Article in Italian]

Grasso M, Castelli M, Lania C, Scattoni V, Radice F, Rigatti P.

Divisione di Urologia, Istituto Scientifico H San Raffaele, Milano.

Impotence following transurethral prostatectomy is one of the main
complications that still has a controversial origin. Many authors, reporting
their experience, have demonstrated that this complication is due both to
psychological problems and to organic causes. We review retrospectively 68
patients submitted to TURP. All patients (53 to 65 years old) were asked
about their sexual efficiency before and after TURP, 6-12 months after
surgery. Those who complained of erectile failure have been studied using
this diagnostic protocol: plasmatic dosage of FSH, LH, Testosterone and
Prolactin; penile Doppler ultrasound, polysomnographic recording of
nocturnal tumescence test (NPT Test); angiography of the pudenda arteries
has been performed in only one patient with pathological penile Doppler
ultrasound (IPP < 0.7). The examinations demonstrated an organic impotence
not secondary to vascular damage in 10 patients following surgery (incidence
15.6%). Our high incidence of this complication is, according to us,
significant even if it should be considered in excess since in our study we
used anamnestic criteria alone in the evaluation of sexual efficiency before
surgery. In 1984 T. Lue demonstrated, through accurate histological
preparations, that cavernous nerves run contiguously to the prostatic
capsule at 5 and 7 hours in correspondence of the glandular apex. He
suggested that impotence following TURP is due to iatrogenic lesions of
these nervous structures during endoscopic resection. Similarly, we have
conducted an anatomopathological study on prostate specimens taken from
autopsies. We demonstrated the presence of nervous structure contiguously to
the prostatic capsule in correspondence with the glandular apex. Thus,
impotence following TURP probably occurs after an iatrogenic heat lesion of
the periprostatic plexus caused by resection.(ABSTRACT TRUNCATED AT 250
WORDS)

PMID: 8278875 [PubMed - indexed for MEDLINE]

> First, you didn't answer my question. Second, I don't believe these
> numbers because they defy credibility. Twenty percent permanent
[quoted text clipped - 46 lines]
> > they are pressed for the info plus they will tell you that retro is a high %
> > too if a TURP is done
riserman@optonline.net - 13 Jul 2004 04:06 GMT
Here's my problem:

If Turp's cause 15.6 percent impotence, how come this information (based
on a really small study of 68 patients) is only available in some
obscure Italian publication? The other question that occurs to me is why
should the results from PVP's be any different? Both TURP's and PVP's
involve large tubes pushed up the penis into the bladder to facilitate a
constant irrigation during the procedures. If there is any solid
statistical support for these high numbers, I would think the cause
would be all the stretching caused by the irrigation tubing. I also note
that apparently the Italian article does not claim TURP's cause
incontinence.

Bob

> I found this on Medline. It shows 15.6 percent.
>
[quoted text clipped - 101 lines]
> high %
> > > too if a TURP is done
Burr - 13 Jul 2004 14:11 GMT
Hi again

I searched Google for web sites using key words "TURP mortality" and this
was at the top of the list. I could have read the thousands that followed
but since you are the one who is interested why not try it yourself. I saw
several that mentioned the 0.25 percent death rate and none were below the 1
in 20 incompetance rate. Just go to www.google.com and you will find more
verification than you can read.

Hope this helps

Burr

> Here's my problem:
>
[quoted text clipped - 116 lines]
> > high %
> > > > too if a TURP is done
Xes@ nospam.com - 13 Jul 2004 13:11 GMT
SNIP
>To date, I haven't seen a message on this board that reports anyone
>dying after PVP or anyone reporting incontinence or impotence.  

I myself suffered incontinence and impotence after PVP  before I died.

SNIP
>I, myself, am still waiting for some improvements in PVP, as my
>situation is not critical.  However, if I should someday find myself
>blocked, I would submit to a PVP procedure in a moment.
I suggest that,  instead of having a PVP,   you have a head
transplant..

Both you and us would benefit.
 
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