Botox for BOH

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jay1000 - 29 May 2006 05:11 GMT

Botox Eases Symptoms of Enlarged Prostate

A small study of patients with benign prostatic hyperplasia, also known as
BPH or an enlarged prostate, shows Botox helps ease the condition, without
major side effects.

The study of 41 men conducted by researchers at the University of Pittsburgh
School of Medicine and Chang Gung University Medical College in Taiwan
involved delivering Botox injections directly into the prostate glands of
patients between ages 49 and 79.

Results show 75 percent of the men reported a 30-percent improvement in
symptoms and quality of life following the treatment. Another 80 percent of
patients were able to empty their bladders completely one week to one month
after treatment.

SOURCE: American Urological Association Conference, Atlanta, May 20-25, 2006

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fgomsan@gmail.com - 29 May 2006 08:27 GMT

Interesting, isn't it?
This was presented at the American Urological Association meeting. The
evidence is still very preliminary, with only small groups of patients
having been treated. Botox paralizes smooth muscle and as you know
smooth muscle tone of the prostate and bladder neck account for the
"dynamic" component of obstruction. Relaxation of smooth muscle is the
mechanism of action of Flowmax and other alpha blockers.
The only problem is that Botox's duration of action averages 6 months.
So it would need to be a repetitive treatment. Too early to be
recommended, but an interesting and minimally invasive idea... We will
have to wait and see what happens. I am sure next year's congress will
be filled with papers on this.

Fernando Gómez Sancha
http:/drgomezsancha2.blogspot.com

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jay1000 - 30 May 2006 04:59 GMT

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Jesse - 30 May 2006 16:00 GMT

Is any doctor in New York City doing Botox shots for BPH?

> Interesting, isn't it?
> This was presented at the American Urological Association meeting. The
[quoted text clipped - 17 lines]
>
> Jay

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Bong - 31 May 2006 00:06 GMT

Yikes!!! Some of you are saying you don't mind if they PERFORATE your
bowel --POKING A NEEDLE THROUGH YOUR BOWEL--to introduce the foreign
substance into your prostate. Don't you realize that each injection is
risk in itself? Going through a dirty contaminated bowel with a needle that
will then carry that dirt and bacteria directly into the Prostate where the
bacteria can then flourish??? A really, really dumb decision! And,
doctors who should be looking out for patient interests, are offering this?!
Has this world gone mad? Isn't anyone thinking beyond the quick fix to the
longer term side effects of anything anymore-- a bit of an exaggeration, but
I'm trying to make a point about patient care going downhill and fast in the
name of a quick fix? By the way, is Botox a regulated substance or can any
corner store get into Prostate Injections with it?

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Gordon Burditt - 31 May 2006 00:56 GMT

>Yikes!!! Some of you are saying you don't mind if they PERFORATE your
>bowel --POKING A NEEDLE THROUGH YOUR BOWEL--to introduce the foreign
[quoted text clipped - 3 lines]
>will then carry that dirt and bacteria directly into the Prostate where the
>bacteria can then flourish???

They do that with prostate biopsy already, except to take samples
out (and I'm sure there is also possibility of putting germs in
along the way - I was given antibiotics to take afterwards). And
I think they did it over a dozen times in one biopsy. I had one
on no more justification than the doctor feeling a lump in the
prostate and a PSA of 0.8 and minor complaints of getting up at
night to pee. I suppose it was to rule out prostate cancer even
though the PSA didn't indicate it.

So, by the time you become a candidate for this procedure, what
percentage of people have ALREADY had needles poked through their
bowel in diagnostic procedures?

>A really, really dumb decision! And,
>doctors who should be looking out for patient interests, are offering this?!
>Has this world gone mad?

I wondered that when the anesthesia from a colonoscopy came darn
close to killing me by leaving me barely conscious (but somehow
they got me out of the hospital anyway) until I died of dehydration,
home alone. Anesthesia is a risk, too.

>Isn't anyone thinking beyond the quick fix to the
>longer term side effects of anything anymore-- a bit of an exaggeration, but
>I'm trying to make a point about patient care going downhill and fast in the
>name of a quick fix? By the way, is Botox a regulated substance or can any
>corner store get into Prostate Injections with it?

I won't comment on the sanity of injecting Botox in particular into
the prostate because I don't know enough about it.

Gordon L. Burditt

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jay1000 - 31 May 2006 02:19 GMT

> Yikes!!! Some of you are saying you don't mind if they PERFORATE your
> bowel --POKING A NEEDLE THROUGH YOUR BOWEL--to introduce the foreign
[quoted text clipped - 9 lines]
> regulated substance or can any corner store get into Prostate Injections
> with it?

I'm no expert but I read somewhere that the prostate can be injected without
going through the bowel. I think it's called penoscrotal injection. Might
be just as bad as going through the bowel.

There is also a device for injecting alcohol directly into the prostate for
BPH control. Maybe the device can be modified for Botox.

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Pete - 31 May 2006 02:59 GMT

> Yikes!!! Some of you are saying you don't mind if they PERFORATE
> your bowel --POKING A NEEDLE THROUGH YOUR BOWEL--to introduce the
[quoted text clipped - 9 lines]
> the name of a quick fix? By the way, is Botox a regulated substance
> or can any corner store get into Prostate Injections with it?

I'm with you on this Bong, if that is the only way of injecting it. Dr.
Sancha, if you are reading this please comment...Pete

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