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Medical Forum / Diseases and Disorders / Prostate BPH / February 2006

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PVP on alarge prostate - Another view

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Midlife - 16 Feb 2006 06:11 GMT
A couple of days ago I posted  (in the continuing large prostate thread)
that I was going for a consult at Clark Urology Center @ UCLA, with Dr.
Robert Reiter, who has been mentioned in this group.  My prostate is 170gms
or so. I had a TUMT about 4 years ago.  TURP has not been suggested by
either my current Uro or Dr. Reiter.

While Dr. Reiter has done successful PVPs on prostates as large as mine, his
opinion is that the best course of action is an open prostatectomy, in which
all but the prostate capsule is removed surgically.  Here's the interesting
part, at least in relation to what I think I've been reading over the past
couple of years:  Dr. Reiter has concluded that the adverse risks of an Open
Prostatectomy are actually of less concern than with a PVP  He finds
Retograde in about 70% of patients with either procedure.  He finds
Incontinence in less than 1% of patients with either procedure.  With PVP
(on such a large prostate) he feels there is likely to be prolonged bleeding
(up to 8 weeks or so); treatable, but not a major issue with the OP.

His basic conclusion is that PVP, on a large prostate, is indicated with
older, less healthy patients, who might not tolerate invasive surgery. I am
62 and otherwise very healthy. With 20+ years of life expectancy, Dr. Reiter
is recommending Open Prostatectomy.

This wasn't exactly what I expected to hear, but it makes sense, given his
experience with side effects.
Bruce@BruceSiegel.com - 17 Feb 2006 18:07 GMT
Hi Midlife,

Interesting.  Have you considered getting a second opinion?  I assume
you live in Southern California (as I do), and the two top PVP doctors
that I know of around here are Dr. Reiter in L.A., and Dr. Laub in
Santa Barbara.  Dr Laub has done even more PVP's than Dr. Reiter, I
believe.  It would be interesting to hear what he has to say.
Let us know what happens.

Bruce
Midlife - 17 Feb 2006 23:03 GMT
> Hi Midlife,
>
[quoted text clipped - 6 lines]
>
> Bruce

I have read about Dr. Laub here as well.  Dr. Reiter WAS a second opinion.
My regular Uro (in Orange County) is a good doctor and has been treating me
for 8 years or so (did my TUMT). But....... I had to tell him about PVP and
he has only done a few two years later, so he had no faith at all in the
possibility of it working on a 170g prostate.  His recommendation was for
Open Prostatectomy, but I didn't feel comfortable taking the word of a
doctor who is not thoroughly familiar with PVP.

Is your comment just general.... or do you have reason to believe Dr. Laub
has a different view of the possible risk %s associated with the two
methods?

Thanks.
Bruce@BruceSiegel.com - 18 Feb 2006 21:35 GMT
I don't have any particular reason to think that Dr. Laub would see it
differently.  For myself, I just try to get as much input as I can
before I make decisions like this.  This is probably a good trait to
have, but to be honest, I sometimes drive myself crazy trying to weigh
and analyze all the options.

Bruce
fgomsan@gmail.com - 21 Feb 2006 00:24 GMT
Open prostatectomy is a good option for a prostate as big as yours. The
results of open prostatectomy are excellent in big prostates, but it
entails a higher risk than PVP. There is risk of incontinence, of
erectile dysfunction, of significant bleeding that might require
transfusion, and you will need a catheter for five days. If you are not
transfused, you will likely be anemic and will need to recover over a
long period of time.

PVP will remove much less tissue than an open prostatectomy, it will
take longer in theatre (up to three hours or more) and will need
several laser fibres if it is to be effective (3 or 4 in my
experience). But it will be safer. I have happy patients after PVP with
prostates up to 200 grams. But the biology of these prostates is to
continue growing and there is a lot of tissue left in place. (the 200
gram prostate patient had a residual volume of approximately 100
grams). An alternative is to try to do a two staged operation, e.g. a
first PVP and then a second PVP some weeks later, to remove as much
hyperplastic tissue as possible. I always mention this possibility to
patients with huge prostates, but they usually feel better after the
first operation and decline to have a second stage. It is true that
patients with huge prostates like yours tend to bleed on an off during
the first six weeks and tend to have a worse postoperative recovery
(more discomfort) than patients with prostates under 70 grams, but
there are no transfusions, no risk of impotence, no other significant
complications.

I have seen wonderful results after open prostatectomy, but i have also
seen a man receiving 24 units of blood during an open prostatectomy,
another man having a cardiac arrest in theatre, incontinent patients
and so on and this would have not happened with PVP.

I understand why Dr. Reiter reached that conclusion, PVP in such big
prostates is a lengthy procedure, and one feels that BPH tissue is
being left in place, so it might regrow. And on the other hand, if you
do not experience serious side effects of open prostatectomy the
chances are you will be cured forever.

You have to decide what risks are more acceptable for you. The
potentially serious side effects of open prostatectomy in exchange for
a good and long lasting result or the less aggressive PVP with a less
predictable result after the first stage.

By the way, never go for a one-hour PVP with one-laser-fiber with such
a big prostate. The only chance of getting a good functional result
after PVP is a very aggressive and very experienced PVP surgeon.

Fernando Gomez Sancha
http://drgomezsancha2.blogspot.com
Pete - 18 Feb 2006 02:15 GMT
> A couple of days ago I posted  (in the continuing large prostate
> thread) that I was going for a consult at Clark Urology Center @
[quoted text clipped - 21 lines]
> This wasn't exactly what I expected to hear, but it makes sense,
> given his experience with side effects.

Midlife...I am curious about something.  When you went to Dr. Reiter (for
your second opinion as stated in your next post), I assume he just did a
digital exam and maybe an ultrasound.  And then he told you about his
recommendation for open prostatectomy.  If you were to follow up on that,
would he have to do a cysto on you first or would he just go ahead and
schedule the surgery based on your estimated prostate size and your
symptoms.  I would think he would do a cysto first, but dunno :-) ...Pete
Midlife - 18 Feb 2006 03:09 GMT
>> A couple of days ago I posted  (in the continuing large prostate
>> thread) that I was going for a consult at Clark Urology Center @
[quoted text clipped - 29 lines]
> schedule the surgery based on your estimated prostate size and your
> symptoms.  I would think he would do a cysto first, but dunno :-) ...Pete

I have an 8+ year history with a Uro and he forwarded the essentials of my
record to Dr. Reiter for the consult.  I presume the results of previous
exams were included, but what Dr. Reiter did was only a flow test and an
ultrasound for urine retention.  I had a rectal a month ago and have had a
number of cystos and 16-point biopsies, as well as numerous ultrasounds over
those years.  What Dr. Reiter would do if I were to schedule a surgery with
him wasn't something we discussed at this point.

One additional fact- I've had a history of urinary infections (maybe 2 per
year, and it is now treated with a daily dose of Septra.  From all that, Dr.
Reiter concluded that my problem is really a bladder problem, and opening
the pathway through the prostate is essential to improving flow and reducing
retention.  

BTW, for those interested, I've had consistent PSa in the low 9's for years.
Biopsies have all been negative, and the conclusion is the high PSA is a
function of prostate size.
 
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