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Medical Forum / Diseases and Disorders / Prostate BPH / August 2005LOWER PSA:
Does anyone in the group have any ideas on how to lower your PSA. DP > Does anyone in the group have any ideas on how to lower your PSA. > DP The way I did it is to first find a doctor who specializes in antiaging. Then you must get all of your hormones in balance, which generally requires maximizing your level of T while keeping DHT and E low. It is still too early to tell what will happen, but initially my PSA was 3.2. After two months of treatment it went to 2.6 and after four months it went to 2.1. I should point out that this treatment should work in theory whether the PSA is caused by BPH or by early stage prostate cancer as shown in my paper at: http://www.tbiomed.com/content/2/1/10 Ed Friedman Ooops - I almost forgot the most important thing. If you are taking 5AR2 inhibitors (which you have to in order to lower DHT), you must avoid all soy, flaxseed, isoflavenes, etc. - anything that binds specifically to ER-beta. Ed Friedman >Ooops - I almost forgot the most important thing. If you are taking >5AR2 inhibitors (which you have to in order to lower DHT), you must >avoid all soy, flaxseed, isoflavenes, etc. - anything that binds >specifically to ER-beta. > >Ed Friedman Interesting... could you provide additional info on this? References? Ed >>Ooops - I almost forgot the most important thing. If you are taking >>5AR2 inhibitors (which you have to in order to lower DHT), you must [quoted text clipped - 6 lines] > > Ed Ed, If you go to the web site: http://www.prostatepointers.org/leibowitz/vitaminlist.10103.html and search for genistein, you will see that this has behavior has been observed in actual patients. The theory comes directly from my paper (the references are in the paper). My next paper will try to clarify this whole issue. But to summarize the first paper: 1.) Mice with a genetic mutation lacking ER-beta have lots of bcl-2 in their prostates. I'm unable to come up with any explanation for this fact other than ER-beta decreases the production of bcl-2 (bcl-2 is what protects prostate cancer from apoptosis). 2.) DHT binding to the intracellular androgen receptor decreases the production of bcl-2. There was a direct experiment that showed that. Therefore, if you are using any drug that lowers DHT production, you are more dependent on ER-beta to keep bcl-2 production low. Since the protein genestein which is found in soy binds preferentially to ER-beta over ER-alpha by a ratio of over 40 to 1, the more soy you take, the lower the rate of apoptosis and the faster the overall growth rate of the prostate cancer population. Ed Friedman >>>Ooops - I almost forgot the most important thing. If you are taking >>>5AR2 inhibitors (which you have to in order to lower DHT), you must [quoted text clipped - 34 lines] > >Ed Friedman ER-beta? bcl-2? Apoptosis? Anyway, I think you are saying that this recommendation is relative to prostate cancer, not BPH. Ed If you are thinking that a high PSA causes cancer, or other problems, and that lowering it will be beneficial, I don't believe that is correct. > Does anyone in the group have any ideas on how to lower your PSA. > DP |
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