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Medical Forum / Diseases and Disorders / Prostate BPH / July 2005

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Number of prostate biopsies

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Ray K - 29 Jun 2005 23:07 GMT
If during an DRE the uro feels a nodule (firm, but not hard), is it
really necessary to take more than one biopsy, right from the nodule? If
there is cancer, it seems to me it would be centered in nodule, so 11
more jabs around the prostate seem unnecessary unless there is some kind
of treatment that is highly localized.
Ed - 29 Jun 2005 23:24 GMT
>If during an DRE the uro feels a nodule (firm, but not hard), is it
>really necessary to take more than one biopsy, right from the nodule? If
>there is cancer, it seems to me it would be centered in nodule, so 11
>more jabs around the prostate seem unnecessary unless there is some kind
>of treatment that is highly localized.

Once they have you there with the probe in place, let them take the
samples they need. It is uncomfortable and stings a bit and is
undignified and stressful, but really it doesn't last long and it is
not that painful.

There could be cancer even if no nodule was felt. I don't think there
is any restriction to where cancer might be (if there is cancer
present).

Take advantage of this excellent medical tool. Let them find out what
is up to perhaps set your mind at rest, or to decide what treatment
you might need. Your life could be at stake...

This was posted to the BPH group. You will probably get better advice
at sci.med.prostate.cancer

Ed
Derek F - 29 Jun 2005 23:57 GMT
> If during an DRE the uro feels a nodule (firm, but not hard), is it really
> necessary to take more than one biopsy, right from the nodule? If there is
> cancer, it seems to me it would be centered in nodule, so 11 more jabs
> around the prostate seem unnecessary unless there is some kind of
> treatment that is highly localized.

You can never have too many. Last time I had 16.
http://www.prostate-research.org.uk/articles/U15A03.htm

Derek.
Ray K - 30 Jun 2005 01:50 GMT
> If during an DRE the uro feels a nodule (firm, but not hard), is it
> really necessary to take more than one biopsy, right from the nodule? If
> there is cancer, it seems to me it would be centered in nodule, so 11
> more jabs around the prostate seem unnecessary unless there is some kind
> of treatment that is highly localized.

Thanks, Ed and Derek, for your comments.

Ray
Michael Balarama - 30 Jun 2005 13:29 GMT
> > If during an DRE the uro feels a nodule (firm, but not hard), is it
> > really necessary to take more than one biopsy, right from the nodule? If
[quoted text clipped - 3 lines]
>
> Thanks, Ed and Derek, for your comments.
Yes but the jabs seem that may help the cancer to spead beyond the nodule

> Ray
Ray K - 30 Jun 2005 21:20 GMT
>>>If during an DRE the uro feels a nodule (firm, but not hard), is it
>>>really necessary to take more than one biopsy, right from the nodule? If
[quoted text clipped - 5 lines]
>
> Yes but the jabs seem that may help the cancer to spead beyond the nodule

Mike, this was a major concern of mine. However, my new doctor said not
to worry about this risk, as it is very low. He was chief pathologist at
Holy Name hospital, Teaneck, New Jersey for over 20 years. He does not
do biopsies, so he has no vested interest in urging me to get them. His
website is majidali.com.

Ray
Ed Friedman - 30 Jun 2005 18:39 GMT
> If during an DRE the uro feels a nodule (firm, but not hard), is it
> really necessary to take more than one biopsy, right from the nodule? If
> there is cancer, it seems to me it would be centered in nodule, so 11
> more jabs around the prostate seem unnecessary unless there is some kind
> of treatment that is highly localized.

The importance in taking multiple cores from around the prostate is in
determining the percentage of cores which show up positive for prostate
cancer.  Basically, if 50% or more come up positive, then there is
almost no chance that localized treatment will effect a cure.

Ed Friedman
Ray K - 30 Jun 2005 21:15 GMT
>> If during an DRE the uro feels a nodule (firm, but not hard), is it
>> really necessary to take more than one biopsy, right from the nodule?
[quoted text clipped - 8 lines]
>
> Ed Friedman

Thanks, Ed, this is the kind of answer I was looking for. The question
then becomes, what exactly is localized treatment? Surgery, yes. Seeds,
yes. Chemo through a catheter directly into the prostate, yes.
Intravenous chemotherapy, no. Whole body radiation, no.

Another question is, just how finely localized can a treatment be?
Suppose just the firm nodule tests positive, but none of the surrounding
other 11 samples do. I wonder what the treatment would be.

Ray
Jack - 02 Jul 2005 16:00 GMT
Assume the nodule does contain cancerous cells.  The next step is to
determine if the cancer has spread outside of the nodule into other parts of
the prostate.  So do it all in one procedure.  That way if it comes back
negative, which we hope you know the prostate is free of cancerous cells.
Jack

> If during an DRE the uro feels a nodule (firm, but not hard), is it really
> necessary to take more than one biopsy, right from the nodule? If there is
> cancer, it seems to me it would be centered in nodule, so 11 more jabs
> around the prostate seem unnecessary unless there is some kind of
> treatment that is highly localized.
 
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