AugmentinES-600 dosage

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Catherine Dodds - 05 Apr 2004 01:26 GMT

The doc perscribed one 600mg/5ml dose every 12 hours for our 80 pound kid's
ear infection. The way we read the box, this is under dosing her. Anyone
help us with the right dose?

Thanks

Mark, Sue and Kate

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Me - 05 Apr 2004 03:32 GMT

> The doc perscribed one 600mg/5ml dose every 12 hours for our 80 pound kid's
> ear infection. The way we read the box, this is under dosing her. Anyone
[quoted text clipped - 3 lines]
>
> Mark, Sue and Kate

The correct dose is a matter of judgement (your doctor's, not some unknown
usenet poster).

There are regular-dose regimens (ranging from 20-45 mg/kg/day), high-dose
ones (80-90 mg/kg/day for known, multi-drug resistant infections), and
then there are no-dose ones for those that agree that ear infections in
children should not automatically be treated with antibiotics.

1200 mg/day of amoxicillin for a 36 kg child is not unreasonable. I'm not
sure why Augmentin ES was chosen (it is usually reserved for the
high-dose regimens, at least in these parts), but maybe the doctor was
thinking that by using it, they would be able to slightly reduce the
amount of clavulanic acid the child would receive with hopes of reducing
stomach upset/diarrhea.

HTH...

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CJ - 05 Apr 2004 12:03 GMT

I took a look in the Sanford Guide for the heck of it. Standard guideline
in otitis media is to give regular amoxicillin and then Augmentin high dose
if antibiotics have already been tried in the previous month.

The doctor might be recognizing that at this point in the season infections
tend to be more resistant to weaker antibiotics, particularly b-lactamase
sensitive ones like amoxicillin. Moderate dose Augmentin would be
satisfactory in such a situation--b-lactamase inhibition without extra nasty
GI problems.

I think this doctor is doing a good job
cjrph

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