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Medical Forum / General / Pharmacy / April 2004

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Visual impairment from steroidal nasal sprays?

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TBrush1090 - 24 Mar 2004 12:03 GMT
A friend of mine was just diagnosed with a mild glaucoma; she's been doing
research on the topic.  Discovered she had a neighbor with similar symptoms.
Neighbor blamed his visual impairment on habitual use of steroid based nasal
sprays such as rhinocort.  

I had never heard of a link between eye trouble and steroid nasal sprays.  Has
this been firmly established?

Thank you.
Tom Gee - 06 Apr 2004 17:00 GMT
> A friend of mine was just diagnosed with a mild glaucoma; she's been doing
> research on the topic.  Discovered she had a neighbor with similar symptoms.
> Neighbor blamed his visual impairment on habitual use of steroid based nasal
> sprays such as rhinocort.  

Isn't that interesting.  Three weeks ago I started having minor vision
troubles in one eye (spots, bit of dazzle).  It was diagnosed by the
optometrist as a migraine aura.  I've had migraines for years but never
with visual (or other) auras.  She said it should go away with my
headache.  It didn't.

I had just started taking Nasonex three weeks before.  During that time,
I had almost incessant mild pain behind both eyes, which I was hoping
would go away as my body adjusted to the medication.

A week ago, my vision became considerably worse, with more apparent
spots and some loss of colour sensitivity.  The opthamologist diagnosed
me as having central and branch retinal vein obstruction from blood
clots, quite a suprising condition as I am otherwise healthy and
only 36 years old.

I have no other (known) underlying conditions.  No glaucoma.  No high blood
pressure.  No high cholesterol (waiting on confirmation of that).
No family history of clotting problems.

> I had never heard of a link between eye trouble and steroid nasal sprays.  Has
> this been firmly established?

In my searches on Medline, it seems that there was a study that showed
that some nasal corticosteroids significantly increased ocular pressure.
In two follow on studies, there was some increase in ocular pressure,
but within normal variations, so they concluded that nasal steroids do
not cause such increases.

So, it makes you wonder, but there doesn't seem to be any firm positive
connections, just negative ones so far.  But as for me, I'm not taking
any more nasal steroids in the forseeable future.  

Tom
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