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Medical Forum / General / Pharmacy / March 2004

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Low level antibiotics

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Dirk Bruere at Neopax - 19 Mar 2004 18:14 GMT
Are there any problems associated with taking very low levels of antibiotics
eg 5% of normal dose, over either the long or short term?

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Dirk

The Consensus:-
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Me - 19 Mar 2004 19:26 GMT
> Are there any problems associated with taking very low levels of antibiotics
> eg 5% of normal dose, over either the long or short term?

Depends upon the antibiotic and why you would be taking it like that.

Sounds like a recipe for creating antibiotic resistance though. Not a good
thing.
Dirk Bruere at Neopax - 19 Mar 2004 22:06 GMT
> > Are there any problems associated with taking very low levels of antibiotics
> > eg 5% of normal dose, over either the long or short term?
[quoted text clipped - 3 lines]
> Sounds like a recipe for creating antibiotic resistance though. Not a good
> thing.

Antibiotic gels absorbed into the skin, for example.

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The Consensus:-
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http://www.theconsensus.org

Darryl - 20 Mar 2004 05:54 GMT
>> > Are there any problems associated with taking very low levels of
>> > antibiotics eg 5% of normal dose, over either the long or short term?
[quoted text clipped - 5 lines]
>
>Antibiotic gels absorbed into the skin, for example.

Resistance to topical erythromycin and tetracycline apparently
develops more easily than with other antibiotics although prescription
of an adjunct may delay the onset of resistance (brief conversation
with a dermatologist I know).  For example, clindamycin and benzoyl
peroxide have been used in the treatment of acne vulgaris.  In acne
rosacea, an adjuct may be contraindicated since it may actually worsen
the symptoms.  If this is for the treatment of acne rosacea, have you
exhausted traditional methods?  Have you tried azithromycin?  Retin-A
or Accutane?

Darryl.
Emma Chase VanCott - 20 Mar 2004 16:22 GMT
: >> > Are there any problems associated with taking very low levels of
: >> > antibiotics eg 5% of normal dose, over either the long or short term?
[quoted text clipped - 5 lines]
: >
: >Antibiotic gels absorbed into the skin, for example.

: Resistance to topical erythromycin and tetracycline apparently
: develops more easily than with other antibiotics although prescription
[quoted text clipped - 4 lines]
: the symptoms.  If this is for the treatment of acne rosacea, have you
: exhausted traditional methods?  Have you tried azithromycin?  Retin-A

Add Metrogel to that list; certainly before Accutane.

Emma
Dirk Bruere at Neopax - 22 Mar 2004 23:46 GMT
> : >> > Are there any problems associated with taking very low levels of
> : >> > antibiotics eg 5% of normal dose, over either the long or short term?
[quoted text clipped - 16 lines]
>
> Add Metrogel to that list; certainly before Accutane.

Metrogel makes it worse.
Have not tried the others, though.

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Dirk

The Consensus:-
The political party for the new millennium
http://www.theconsensus.org

Shirley Gutkowski RDH - 23 Mar 2004 02:06 GMT
>> Are there any problems associated with taking very low levels of
>> : >> > antibiotics eg 5% of normal dose, over either the long or short
>term?

Are you refering to Periostat also known as Dermastat.  20mg doxycycline.  The
chance for resistance is low or not there because there is no antibiotic effect
at that dose.

Shirley Gutkowski, RDH, BSDH
"Everbody wants to save the earth - nobody wants to help Mom to do the dishes."
    - P. J. O'Rourke
~~~~~~~~~
http://www.dentistry.com/poralhealth_02.asp
Dirk Bruere at Neopax - 23 Mar 2004 23:16 GMT
> >> Are there any problems associated with taking very low levels of
> >> : >> > antibiotics eg 5% of normal dose, over either the long or short
[quoted text clipped - 3 lines]
> chance for resistance is low or not there because there is no antibiotic effect
> at that dose.

I'm referring to this:
http://www.kbnet.co.uk/artemis/rosacea/

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Dirk

The Consensus:-
The political party for the new millennium
http://www.theconsensus.org

 
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