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Medical Forum / General / Pharmacy / December 2003

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Can these drugs be used interchangably?

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francispoon - 30 Dec 2003 02:10 GMT
I am living in China and find it difficult to obtain ATIVAN(lorazepam)
without having to go to Hong Kong.  On the other hand, plenty of
alprazolam drugs are available.

Could these 3 categories of drugs, clonazepam, lorazepam or aprazolam
be used interchangably without any adverse effect?  Or are these the
same kind of drugs?  Pardon my ignorance, please.

Thanks,

FP
BilZ0r - 30 Dec 2003 05:24 GMT
Not completely interchangably. They require different dosages, and may
cause slightly different effects. Consult a doctor.

> I am living in China and find it difficult to obtain ATIVAN(lorazepam)
> without having to go to Hong Kong.  On the other hand, plenty of
[quoted text clipped - 7 lines]
>
> FP
William Nunn - 30 Dec 2003 20:21 GMT
I am not a doctor, but what I can say is Clonazepam is thought to be the
most potent benzo with the most difficulty in withdrawing and pronounced
severe withdrawal. Xanax is a bit more potent than Ativan, and slightly
shorter acting I think.
PaulS - 31 Dec 2003 00:46 GMT
> I am not a doctor, but what I can say is Clonazepam is thought to be the
> most potent benzo with the most difficulty in withdrawing and pronounced
> severe withdrawal. Xanax is a bit more potent than Ativan, and slightly
> shorter acting I think.

A good rule of "thumb" is that the shorter-acting (i.e., acts quickly and is
cleared from the body quickly) drug in this category is the most difficult
to withdraw from. Often, a doc will help someone w/d from xanax by
substituting a longer acting benzo.

PaulS
francispoon - 31 Dec 2003 05:31 GMT
> I am not a doctor, but what I can say is Clonazepam is thought to be the
> most potent benzo with the most difficulty in withdrawing and pronounced
> severe withdrawal. Xanax is a bit more potent than Ativan, and slightly
> shorter acting I think.

It depends on the dosage, I suppose.  I would not want to go over
anything more than 0.5 mg.  With 0.5 mg, it enables me to sleep until
about 2-3am in the morning and then the noise comes.  I supplement
this 0.5 mg of ATIVAN with 3 herb capsules.  The latter make my sleep
a bit longer and sweeter.

FP
francispoon - 31 Dec 2003 05:28 GMT
> Not completely interchangably. They require different dosages, and may
> cause slightly different effects. Consult a doctor.

My two doctors said it is ok to use a sub=branch of Aprazolam as a
substitute.  By the way, I was unable to sleep even with 0.5 ATIVAN
last night, but i am feeling fine today in day time.  Wonder why?

FP
======================================

> > I am living in China and find it difficult to obtain ATIVAN(lorazepam)
> > without having to go to Hong Kong.  On the other hand, plenty of
[quoted text clipped - 7 lines]
> >
> > FP
 
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