Itraconazole for treatment of nail fungus

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Dan24 - 29 Jul 2008 16:55 GMT

Hi,

I was recently prescribed this medicine after I have been diagnosed
for having nail fungus.
My doctor prescribed me Itranol (by Liconsa, contains 100mg
Itraconazole) and when I specifically asked him about Lamisil he said
that he believes that for my specific type of nail fungus this would
be more effective.
Since I always prefer to be mainstream, I wanted to ask if I should
insist on taking Lamisil (I've read there is less risk associated and
it's more effective?).

Please advise!

Thanks in advance,

Dan

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Protoman - 29 Jul 2008 22:13 GMT

> Hi,
>
[quoted text clipped - 13 lines]
>
> Dan

My physician prescribed me Gris-PEG (PEGylated griseofulvin), and it
works as well or better, as well as being far cheaper then
itraconazole or terbinafine (Lamisil). Ask your internist for a six
month course of Gris-PEG, and you should be rid of that fungal
infection.

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mopurist - 30 Jul 2008 01:45 GMT

> My physician prescribed me Gris-PEG (PEGylated griseofulvin), and it
> works as well or better, as well as being far cheaper then itraconazole
> or terbinafine (Lamisil). Ask your internist for a six month course of
> Gris-PEG, and you should be rid of that fungal infection.

I'm glad that the Gris-PEG worked for you. However...

I just wanted to add that you can't get any cheaper than _generic_
lamisil tablets, even without insurance. It is on Walgreens'
"prescription savings club" price list for $9.99/#30 $12.99/#90 and
Walmart's low-cost generics list ($4/#30).

Brand-name Lamisil tablets will still cost you ALOT more (up to 80x based
on cash price).

So if the OP really wanted the Lamisil, he could ask his Dr for it based
upon price alone.

As far as which works better, I'm afraid I don't have an answer. Locally
I see Rxs for Lamisil outnumber itraconazole about 8:1, if not more, and
rarely see an Rx for any form of griseofulvin. Generally, depending upon
who you ask or which studies you read, griseofulvin is considered the
least effective of the 3. Not to say it doesn't work, but statistically,
its success rate is lower and its use typically requires longer treatment
that the other two.

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Protoman - 31 Jul 2008 00:43 GMT

> > My physician prescribed me Gris-PEG (PEGylated griseofulvin), and it
> > works as well or better, as well as being far cheaper then itraconazole
[quoted text clipped - 21 lines]
> its success rate is lower and its use typically requires longer treatment
> that the other two.

I see. And combing oral terbinafine w/ amorolfine nail lacquer has
been proven in clinical studies to result in a higher cure percentage
then oral terbinafine alone. You should also have your dermatologist
debride the infected nail.

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Dan24 - 31 Jul 2008 13:15 GMT

> > > My physician prescribed me Gris-PEG (PEGylated griseofulvin), and it
> > > works as well or better, as well as being far cheaper then itraconazole
[quoted text clipped - 26 lines]
> then oral terbinafine alone. You should also have your dermatologist
> debride the infected nail.

The fungus was diagnosed as: Scopulariopsis sp
Does this indeed confirm that Itraconazole is more suited?

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