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Medical Forum / General / Pharmacy / May 2008

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Should The FDA put a warning on Sodium Phosphate Enemas?

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chorleydnc@gmail.com - 26 May 2008 05:26 GMT
There are about 30 incidences of  irreversible renal failure in
(mostly women) who are routinely taking either ARBs or ACEIs and
undergoing bowel prep for surgery or colonoscopy. Sodium Urate
crystals form in the interstitium of the kidney.
Anyone can buy a Fleets Sodium enema without warning. It would be a
useful activity of this group to disseminate this information and
bring to the public and the FDA the idea that both the medication and
the enema should carry a black box warning.

David
chorleydnc@gmail.com - 26 May 2008 16:24 GMT
On May 25, 11:26 pm, "chorley...@gmail.com" <chorley...@gmail.com>
wrote:
> There are about 30 incidences of  irreversible renal failure in
> (mostly women) who are routinely taking either ARBs or ACEIs and
[quoted text clipped - 6 lines]
>
> David

Crystals are calcium phospate salts, not urate, sorry for the error
David
Dr. Wayne Simon - 26 May 2008 23:20 GMT
> On May 25, 11:26 pm, "chorley...@gmail.com" <chorley...@gmail.com>
> wrote:
[quoted text clipped - 11 lines]
> Crystals are calcium phospate salts, not urate, sorry for the error
> David

I do remember an oncologist friend of mine telling me that one must be
careful in certain patients because there are occassions the phosphate
enemas can result in hypocalcemia.
chorleydnc@gmail.com - 27 May 2008 00:25 GMT
> <chorley...@gmail.com> wrote in message
>
[quoted text clipped - 19 lines]
> careful in certain patients because there are occassions the phosphate
> enemas can result in hypocalcemia.

Well, not only that, remember, if your Calcium Phosphate product
exceeds 55 (in US values) you run the risk of dystrophic
calcification.
David
 
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