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Medical Forum / General / Pharmacy / March 2008

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Geneic Lexapro?

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me@privacy.net - 28 Feb 2008 13:58 GMT
Does there exist a cheap generic for Lexapro?

Or another generic SSRI as good as Lexapro for general
anxiety control?
Salmon Egg - 28 Feb 2008 19:59 GMT
> Does there exist a cheap generic for Lexapro?
>
> Or another generic SSRI as good as Lexapro for general
> anxiety control?

Although someone marked this post as junk, it does not seem like a junk
post. True, it is full of spelling and grammatical error. While that
would turn me off or put me to sleep, it does not seem like serious junk.

Bill
mred - 29 Feb 2008 00:33 GMT
>Does there exist a cheap generic for Lexapro?
>
>Or another generic SSRI as good as Lexapro for general
>anxiety control?

Lexapro, chemical name escitalopram  isn't available as a  generic.
Citalopram brand name Celexa, is a very similar less expensive generic
alternative.
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mred

Salmon Egg - 29 Feb 2008 01:10 GMT
> Lexapro, chemical name escitalopram  isn't available as a  generic.
> Citalopram brand name Celexa, is a very similar less expensive generic
> alternative.

Although it is not my expertise, I do know that Citalopram is a mixture
of two enantiomers. That is a 50-50 mixture of what is Lexapro and its
mirror image molecule. Lexapro. Only the Lexapro (the left-handed
molecule) is active. The right-handed version present. If all is well,
there will be no harm from this right-handed molecule.

Bill
mred - 29 Feb 2008 12:32 GMT
>> Lexapro, chemical name escitalopram  isn't available as a  generic.
>> Citalopram brand name Celexa, is a very similar less expensive generic
[quoted text clipped - 7 lines]
>
>Bill

Exactly, drug companies use this technique to continue a revenue
stream, that otherwise dries up after the brand name patent expires.
People knowledgeable, physicians, pharmacists can steer patients to
considerably less expense, very similar alternatives.
See the book The Truth About the Drug Companies: How They Deceive Us
and What to Do About It. Written by Marcia Angell

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mred

Salmon Egg - 01 Mar 2008 00:35 GMT
> Exactly, drug companies use this technique to continue a revenue
> stream, that otherwise dries up after the brand name patent expires.
[quoted text clipped - 3 lines]
> and What to Do About It. Written by Marcia Angell
>  

What I do not understand is the legal basis upon which new patents can
be issued for a single pure enantiomer. I would think that in most
cases, the technology to extract a pure enantiomer is well known to a
competent chemical practitioner and does not require the innovation
deserving of a patent.

The same comment applies to time release medications. What is the
inventive spark to that?

Bill
mred - 02 Mar 2008 15:01 GMT
>> Exactly, drug companies use this technique to continue a revenue
>> stream, that otherwise dries up after the brand name patent expires.
>> People knowledgeable, physicians, pharmacists can steer patients to

>What I do not understand is the legal basis upon which new patents can
>be issued for a single pure enantiomer. I would think that in most
[quoted text clipped - 6 lines]
>
>Bill

Legal basis, not sure. I would think the original patent includes both
isomers. So why don't they both expire? Its not really a novel
compound. Probably need a patent attorney to explain. The PBM's are on
to this practice, they almost never pay for newer items, without prior
authorization  or tiered co-pays. The drug manufactures are trying to
protect bottom line, because low numbers of new drugs currently in
pipeline.

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mred

Salmon Egg - 02 Mar 2008 18:40 GMT
> Legal basis, not sure. I would think the original patent includes both
> isomers. So why don't they both expire? Its not really a novel
[quoted text clipped - 3 lines]
> protect bottom line, because low numbers of new drugs currently in
> pipeline.

As much as I detest parasitical pharmaceutical companies, just because a
compound is known does not preclude patents for its manufacture. For
example, ammonia was a well known  compound before the Haber process for
manufacturing it was developed. Haber deserved to be considered an
inventor.

My argument is that many of the processes used for manufacture afre
likely to be what any competent chemical engineer could do one he or
possibly she, knows of similar previously known manufacture.

Bill
mred - 02 Mar 2008 22:50 GMT
>> Legal basis, not sure. I would think the original patent includes both
>> isomers. So why don't they both expire? Its not really a novel
[quoted text clipped - 15 lines]
>
>Bill

How about the same drug, but different strength. How is that patent
protected? I guess I have to research patent law.
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mred

JoyJohn - 12 Mar 2008 08:31 GMT
>Does there exist a cheap generic for Lexapro?
>
>Or another generic SSRI as good as Lexapro for general
>anxiety control?

Yes there is generic Lexapro (Escitalopram) available for good quality and
cheap price. You can find at
http://www.internationaldrugmart.com/lexapro.html

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