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Medical Forum / General / Pharmacy / January 2008question about Lisinopril
Our doctor said my husband's kidney function wasn't up to par - creatinine was too high (1.4) and he has some protein in his urine. She put him on Lisinopril 5mg. I read the info on this drug and I don't see anywhere that it's indicated to improve kidney function. In fact it warns against using it for people with renal impairment. I'm really confused. Another question: he feels slightly light headed this morning (his first dose was at bedtime last night). I took his bp and it was down, but not a lot (110/63). Does the light headed feeling eventually go away? Yes, I know these are questions for our doctor and I plan to ask her. The trouble is she's on vacation right now. thanks. That drug is mainly a blood pressure pill. Actually when I took it I coughed non stop for a year until I convinced my doc to take me off of it. Talk to another doctor if yours is gone. Jackie > Our doctor said my husband's kidney function wasn't up to par - > creatinine was too high (1.4) and he has some protein in his urine. [quoted text clipped - 14 lines] > > thanks. > That drug is mainly a blood pressure pill. Actually when I took it I > coughed non stop for a year until I convinced my doc to take me off of it. [quoted text clipped - 18 lines] > > > thanks. Lisinopril is known as an ACE inhibitor - which is an enzyme system that controls your blood pressure among other things mainly through the kidneys. It actually is renoprotective - meaning it helps preserve kidney function. Your husbands Cr is a little high, but is also depends on your age as to whether that is a problem, and to his body build. One of the major side effects to any ACE is orthostatic hypotension - which is the feeling of being light headed upon standing. This should normalize within a week though, and he shouldn't suffer from it anymore. Continue to have him take his doses at night - so that it doesn't interfere with any problems driving/at work/etc. The cough that the other user posted about is another major side effect - but it only happens in about 10-15% of those taking the medication - and your husband is on a very low dose (mainly because the doc isn't using to control BP) so I would guess he shouldn't experience any problems. Over the counter cough medications won't help take away the cough, so don't waste your money. If he does develop a cough though, you will need to rule out that it isn't just the common cold. And the final side effect to worry about is facial swelling, but this one happens in less than 1% (probably even less than that), and he would have experienced it by now if it was a problem. Hope this helps. Your doctor actually has chosen a very good medication if she is worried about your husbands kidney function I agree with the other two responses. Lisinopril is used to treat hypertension, either alone or in combination with other antihypertensive drugs. Some people do stop using it because of chronic coughing. Lisinopril is used as assistive therapy to treat heart failure because it reduces the pressure that the heart is pumping against. The pressure the heart is pumping against is called afterload and this use is called afterload reduction. Afterload reduction improves renal blood flow because it causes cardiac blood flow to increase. Lisinopril is used to preserve renal function. For example, it helps diabetic patients, with or without slight proteinuria, to prevent progression to readily observable proteinuria and renal disease. It works in diabetic patients with and without hypertension. It reduces proteinuria and preserves renal function in patients who already have renal disease. Lisinopril is used to preserve renal function in hypertensive renal transplant patients. 1) Sudden dizziness or dizziness on standing are dose related. Reducing the dose can help to minimize their occurrence and their intensity. The tablets you have are probably scored and treatment could be started with half a tablet. 2) The dizziness is accommodated and countered, to some extent, by biochemical mechanisms operating within the body. It may or may not go away (depending on the dose, affinity of active agent for sites of action, and unknown patient factors). 3) Some people reporting dizziness from medications have subsequently fallen and broken hips, shoulders, and ribs. Others have suffered life-threatening hematomas and concussions. Therefore, this kind of side effect should never be minimized when it occurs, especially if it continues or causes falling or unsteadiness. Here is a recent internet posting about this issue. In this case, lisinopril is being used with a thiazide diuretic which can make the situation worse: ====================================================== Side Effects posted for Hydrochlorothiazide-Lisinopril http://www.medications.com/se/hydrochlorothiazide-lisinopril ====================================================== December 21th 2007 7:57 AM I keep getting dizzy, quick blackout and fainting spells since taking this medication. I also get sweats/chills. I also urinate more and am always tired. I am thinking it may be from the medication but my doctor says no and I am not sure I believe him unfortunately. Did anyone else have these spells when taking lisinopril? ====================================================== > Our doctor said my husband's kidney function wasn't up to par - > creatinine was too high (1.4) and he has some protein in his urine. [quoted text clipped - 14 lines] > > thanks. |
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