"With food" NSAID & Liver?

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vjp2.at@at.BioStrategist.dot.dot.com - 12 Jun 2007 09:09 GMT

When they say you need to take ibuprofen or acetamenaphen with food to
prevent liver damage, what do they mean? A friend's daughter nearly needed a
transplant. I wonder, if it is like a certain amout of protein or fiber or
calcium carbonate buffer, why they don't just include it in the pill?

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Vasos Panagiotopoulos, Columbia'81+, Reagan, Mozart, Pindus, BioStrategist
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Menno - 12 Jun 2007 20:17 GMT

> When they say you need to take ibuprofen or acetamenaphen with food to
> prevent liver damage, what do they mean?

I think "they" are a bit confused. Ibuprofen can cause irritation of the
wall of the stomach when taken upon an empty stomach. Taking it with food
can reduce that. Acetaminophen can cause liverdamage in high dosages, but
taking it with food won't help in preventing that.

Menno

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mred - 12 Jun 2007 23:50 GMT

> When they say you need to take ibuprofen or acetamenaphen with food to
>prevent liver damage, what do they mean? A friend's daughter nearly needed a
>transplant. I wonder, if it is like a certain amout of protein or fiber or

Food is to minimize stomach upset. Food doesn't diminish the
potential for liver damage, which is low if you stick to the guideline
for acetaminophen. Less than 4 gm/day and 1 alcoholic drink or less
/day.

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mred

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