SSRI - How do the affect Premature Ejaculation?

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john2112 - 17 Oct 2003 15:10 GMT

SSRIs have been used for treating depression and premature ejaculation (PE).

How does an SSRI delay ejaculation? Would anyone be able to explain the process?

Does it work on muscles in the scrotum? Does it affect blood flow in that area?

Are there any drugs developed or in the research stage SPECIFICALLY for PE?

Thank you for your time,

JS

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Alan Young - 18 Oct 2003 01:33 GMT

> SSRIs have been used for treating depression and premature ejaculation (PE).
>
[quoted text clipped - 3 lines]
> Does it work on muscles in the scrotum? Does it affect blood flow in that
> area?

Just an amateur psychologist's opinion here:
PE is assumed to be caused by psychological, not physiological, factors.
So drugs that affect brain chemistry and mood, particularly to reduce
anxiety, would seem to be appropriate.

> Are there any drugs developed or in the research stage SPECIFICALLY for
> PE?

If there were, it would be a bad idea to start relying on them--
assuming that PE is one symptom in an emotional disorder. Wouldn't you
rather have your overall emotional life improved, instead of just your
ejaculations?

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BilZ0r - 19 Oct 2003 05:50 GMT

Im not sure, I would geuss (becasue they cause erectile disfunction too)
that they are effecting smooth muscle in the vasculature in the penis.
Decrease the blood flow, decrease the sensitivity, decrease the
ejaculation.

But it could be of a central origin too. Interesting question, I might
look it up, see if anyones looked at that.

> SSRIs have been used for treating depression and premature ejaculation
> (PE).
[quoted text clipped - 11 lines]
>
> JS

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john2112 - 23 Oct 2003 02:08 GMT

It is interesting. This drug could delay PE but prevent erection.
Talk about contradiction!

I am surprised there has been no dedicated drug for PE - it would make
a killing.

But it also makes me wonder - is PE truly psychological or physical -
or a bit of both.

Origianlly erectile dysfunction was treated as if it was all in the
head, later - it was realized there were many physical factors. Drugs
like Viagra came out. Even more invasive drugs like papaverine,
prostaglandin E (sp?). Even vaccum tube devices.

What is the real cause of PE?

Thanks,

JS.

> Im not sure, I would geuss (becasue they cause erectile disfunction too)
> that they are effecting smooth muscle in the vasculature in the penis.
[quoted text clipped - 19 lines]
> >
> > JS

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BilZ0r - 23 Oct 2003 03:02 GMT

PE is "in your head" but that dosn't neccasarily mean it can be treated
by just thinking about it. Like depression,

Theres nothing physically wrong with the penis.

> It is interesting. This drug could delay PE but prevent erection.
> Talk about contradiction!
[quoted text clipped - 39 lines]
>> >
>> > JS

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