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Dylan Kim - 19 Sep 2006 21:24 GMT

Simple though but I don't seem to understand under what mechanism can a
tablet recognize the main protein to which it should attach and where
does the main reason for so-called by-product effects by drug overdose
lie ? i am looking for a relation in between
Thansk

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Dr. Wayne Simon - 19 Sep 2006 22:41 GMT

> Simple though but I don't seem to understand under what mechanism can a
> tablet recognize the main protein to which it should attach and where
> does the main reason for so-called by-product effects by drug overdose
> lie ? i am looking for a relation in between
> Thansk

The tablet doesn't attach to anything. The active ingredient, which
dissolves and then absorbs into the blood stream, has a chemical
which has the affinity and steriospecificity to attach to the protein
(receptor), where it's pharmacological effects are to be initiated.
Sometimes the actual clinical effect is a post receptor effect. The side
effects usually are a result of the medication, attaching to other
like receptors which may not be the targets of the drug, but may not be
easily differentiated.

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Dylan Kim - 20 Sep 2006 00:47 GMT

Dr. Wayne Simon เขียน:

> The tablet doesn't attach to anything. The active ingredient, which
> dissolves and then absorbs into the blood stream, has a chemical
[quoted text clipped - 4 lines]
> like receptors which may not be the targets of the drug, but may not be
> easily differentiated.

thanks for the reply, I mistook the tablet with its components :4(
Ok, I'll check it again and think :9)

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