Ibuprofen

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Steven - 17 Jul 2006 03:52 GMT

When I take an Advil, I notice a significant reduction in my urinary output.
I have no known renal problems. Should I be concerned about this, is it
safe for me to use?

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Dr. Wayne Simon - 17 Jul 2006 05:51 GMT

> When I take an Advil, I notice a significant reduction in my urinary
> output.
[quoted text clipped - 6 lines]
>might be wise to see your physician for an educated benefit risk analysis
>on your medication regimen.

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Steven - 18 Jul 2006 04:07 GMT

"> Dr. Wayne Simon" <wayne.simon@comcast.net> wrote in

> message news:xs-dnYDERsLRiibZnZ2dnUVZ_sOdnZ2d@comcast.com...
>
> > When I take an Advil, I notice a significant reduction in my urinary
> > output.
> > I have no known renal problems. Should I be concerned about this, is it
> > safe for me to use?

> Some folks have kidneys that are more dependent on the prostaglandin
> function. If your kidneys are highly dependent on the functioning of your
> prostaglandins, than ibuprofen may have a negative effect on renal
> function. Depending on whether you need to take this medication or not,
> it might be wise to see your physician for an educated benefit risk
> analysis on your medication regimen.

Thanks for the reply. Are there any OTC pain relievers that don't interfere
with prostaglandin synthesis?

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Dr. Wayne Simon - 18 Jul 2006 06:13 GMT

> "> Dr. Wayne Simon" <wayne.simon@comcast.net> wrote in
>> message news:xs-dnYDERsLRiibZnZ2dnUVZ_sOdnZ2d@comcast.com...
[quoted text clipped - 14 lines]
> interfere
> with prostaglandin synthesis?

Acetaminophen (paracetamol) is a non anti inflammatory pain reliever that
only blocks prostaglandins in central tissues and not in the kidneys. But
tylenol does in high dose cause liver problems. In regular doses that
should not be a problem.

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Steven - 18 Jul 2006 17:28 GMT

>> "Steven"
>>
[quoted text clipped - 18 lines]
> in the kidneys. But tylenol does in high dose cause liver problems. In
> regular doses that should not be a problem.

"Steven"

I would use Acetaminophen for a headache, fever or flu symptoms,

but for muscle ache, back pain or other inflammatory aliments

I would need an NSAID. The question now is if I use

ibuprofen occasionally am I causing renal damage?

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