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Medical Forum / General / Pharmacy / October 2003Generic Vs. Brand
Is it a true statement that a Generic drug only needs to have 75% of the active ingredient of the Brand. I have heard this from several Doctors and want to know whether it is true. thanks, ken NO > Is it a true statement that a Generic drug only needs to have 75% of the > active ingredient of the Brand. I have heard this from several Doctors and > want to know whether it is true. > > thanks, ken > Is it a true statement that a Generic drug only needs to have 75% of the > active ingredient of the Brand. I have heard this from several Doctors and [quoted text clipped - 3 lines] > >================= Change Doctors... Seriously I respect physicians BUT doubt ANY would make such a statement. It is flat out wrong ! Bob Griffiths > > Is it a true statement that a Generic drug only needs to have 75% of the > > active ingredient of the Brand. I have heard this from several Doctors and [quoted text clipped - 9 lines] > > Bob Griffiths Generic drugs and brands are allowed a certain range of values from the average amount of drug in a particular tablet. If the tablet is supposed to contain 325 mg of aspirin (labeled amount), it may in fact contain plus or minus a certain percentage. Maybe ten percent. Then the tablet could contain from 292 mg to about 357 mg of aspirin and still be within specifications. On a drug like ferrous sulfate (iron tablet) ten percent or maybe more would be nothing to be worried about. A drug like warfarin would have a tighter range. Perhaps some fairly harmless drugs can have 75% of the labeled active ingredient and still be OK and meet the government standards. A drug like Premarin extracted from horse urine probably has a wide variation between lots of the brand name. It also makes it extremely hard to duplicate as each lot is different. Nope. Generic and brand name drugs are held to the same standards. Brad > Is it a true statement that a Generic drug only needs to have 75% of the > active ingredient of the Brand. I have heard this from several Doctors and > want to know whether it is true. > > thanks, ken |
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