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Medical Forum / General / Pharmacy / December 2005

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Dispensing Actiq to non-cancer patients

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ringmaruf2@jesuisbern.com - 20 Dec 2005 22:08 GMT
How hard is it to get a pharmacist to dispense Actiq (fentanyl
lozenges) to a non-cancer patient?  I recently read a study in the
journal Headache that supported their use in intractable migraine as an
alternative to going to the emergency room, and I plan to discuss that
with my neurologist when I see her next week.  I suffer from
debilitating migraines, and take Keppra and Inderal LA for prophylaxis,
but that just managed to get the number down from 6-8 per month to 2-3
per month.  I take a number of drugs prn on an acute basis, but they
often fail, and the standard opioids don't touch the bad migraines.
Additionally, I need non-oral formulations, as I get severe vomiting
with my migraines.  Right now, we're using Dilaudid suppositories.
Still, I'm often not able to get rid of the migraines after 3 days or
so, and I wind up in the emergency room about 3-4 times a year, and
even there, it can take several rounds of various drugs to get the
migraines to remit.  I think that Actiq is definitely worth a try for
those situations, to save the time, hassle, and expense of a trip to
the ER, even some of the time.  I just wanted to inquire before talking
to my neurologist about how hard it might be to get the script filled,
should she choose to prescribe it.  One of the other opioids we tried
earlier was methadone, and I found that could be difficult to get
filled for acute pain, and many pharmacies in the area choose not to
stock it at all.

Thanks.
Pumbaa - 21 Dec 2005 00:11 GMT
> How hard is it to get a pharmacist to dispense Actiq (fentanyl
> lozenges) to a non-cancer patient?  I recently read a study in the
[quoted text clipped - 20 lines]
>
> Thanks.

Is your doctor on the staff of a good hospital that will fill outpatient
prescriptions?  A hospital usually stocks all sorts of control substances
and has a lot better security than the average pharmacy (none - I have seen
in most pharmacies where I live except for the VA system).

When I worked as a hospital Pharmacist we had a patient that had intractable
migraine.She was taking the following every two weeks.  She got 100 ampules
of Codeine Injection 30 mg and about 10 ampules of Demerol 100 mg.
Injection. She took this for years but she never increased the dosage.  This
was approved by the medical staff and the chief of Pharmacy.  Even so,  some
pharmacists did not want to fill her prescriptions.  I didn't want to fill
them at first but eventually I got used to the idea.

Why don't you talk with your doctor and maybe she will know a pharmacy that
stocks and fills Rxs like Actiq.  I used to also dispensed methadone to
patients that could NOT get a local pharmacy to stock the item. In areas
with severe crime problems it just is not worth getting robbed or shot to
stock drugs that are favorites of criminals.
ringmaruf2@jesuisbern.com - 21 Dec 2005 09:01 GMT
> Is your doctor on the staff of a good hospital that will fill outpatient
> prescriptions?  A hospital usually stocks all sorts of control substances
> and has a lot better security than the average pharmacy (none - I have seen
> in most pharmacies where I live except for the VA system).

That's a good idea, thanks for the suggestion, I never would've thought
of that.  She is on the staff at a good hospital, but I'm not sure if
they'd fill outpatient prescriptions.  I will inquire about that.

> When I worked as a hospital Pharmacist we had a patient that had intractable
> migraine.She was taking the following every two weeks.  She got 100 ampules
[quoted text clipped - 3 lines]
> pharmacists did not want to fill her prescriptions.  I didn't want to fill
> them at first but eventually I got used to the idea.

We're really trying to avoid needles, partially because I really don't
like them even a little bit.  :)

Unfortunately, I think we're probably going to be headed in that
direction soon, perhaps not for the opioids at first, but for the
anti-emetics.

And thank God my migraines are nowhere near the point of needing that
level of meds.  Yikes.
oldal4865 - 23 Dec 2005 13:59 GMT
ringmaruf2@jesuisbern.com wrote in message
<1135155599.607972.94780@g47g2000cwa.googlegroups.com>...
. . .(snip). . .

>We're really trying to avoid needles, partially because I really don't
>like them even a little bit.  :)
>. . .(snip). . .

  If any of these meds can be injected under the skin,  then it would be
similar to the insulin injections we T1 diabetics use.

When I first figured out that I was going to need insulin injections,  I
almost threw up.

Now I inject 7 -12 times a day,  every day.    That includes occasional 3
a.m. injections.   No fuss,  no bother.

The turning point for me came during my insulin training.    I walked in
full of dread,  then watched the training nurse casually pull up her blouse
and inject saline into her abdomen,  essentially without interrupting her
lecture.     Talk - talk - talk - inject - talk -talk- talk.

Click!  No more dread.

Regards
 Old Al
Isogenic - 30 Dec 2005 20:38 GMT
I know of two people that take Actiq for their migraines.... both
people take the 600mcg pop. I have cancer and I take the 1600mcg pop
(and 1200mcg pops) as my breakthrough med, and it works extremely well.
I used to take 30mg Roxicodone, and my Actiq is so much better. Good
luck.
 
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