I suppose the answer should be, "not exactly." It depends on how
literal you are intending to be. Drinking small amounts of alcohol
(say, a glass of wine) occasionally is all right for most people on
most psychotropic medications. Drinking large quantities frequently is
not. In that sense, you could say that there is no difference between
the medicated folks and the unmedicated folks, since drinking to
excess is a bad idea anyway.

The difference is that psychotropic meds, and the condition of
depression itself, move the threshold of what constitutes "drinking to
excess." Alcohol is a "depressant," and can exacerbate depression in
people who have it, and thus reduce the usefulness of the medications
taken for depression or other mood disorders. In addition, many
medications specifically warn of possible adverse effects from
combining them with alcohol, which is something that applies to
varying degrees on a per-medication basis.

In short, read the warning labels on your meds, and never drink to
excess (or even very much) if you are taking psychotropic medications.

I can't give you a yes or no answer. It depends on the medication.
Read the information that comes with the medication. If it states--"Don't
drink alcolhol when you use this medication"--follow the instuctions.

If the information that comes with the medication does not mention
alcohol--in most cases--you can drink alcohol when you use that
medication.

I have no idea if its true or not that they don't "chemically mix".  It
really doesn't matter.  Think of your meds as your left arm and alcohol as
your right arm.  Your left arm can do some tasks, your right others and many
task they can do equally well.  Working together they can accomplish a lot
more than alone, sometimes with disastrous results.

Your meds have effects on chemicals in your brain.  Alcohol has effects on
chemicals in your brain.  Some chemicals the same, some different. Its the
net result of these actions that are important, not whether or not they
mixed and had a chemical reaction together.

Bryan