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Medical Forum / General / Pharmacy / September 2003

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Toxicity of triazines

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Jose M. Santos Picallo - 18 Sep 2003 07:20 GMT
Dear Colleages, im interesting im some information about toxicity of
2,4-diamino-6-alkyl-s-triazines (R between 8 and 18 C).
For example 2,4-diamino-6-phenyl-s-triazine is also called Benzoguanamine
and 2,4-diamino-6-undecyl-s-triazines is also called lauroguanamine
Can somebody Help me?

Best Regards
José M. Santos
Diplom-Chemiker
Ciba Spezialitäten Chemie
Coating Effects (CE 703)
R-1049 3.58
P.O. Box 4002
Basel - Switzerland
Tfn:00416163622667 (Intern: 622667)
Handy:0041764568297
mail to : jose_manuel.santos_picallo@cibasc.com
BilZ0r - 18 Sep 2003 11:21 GMT
"Four inactive compounds included m-phenyl-enediamine, 2,4-
dinitrochlorobenzene, benzoguanamine, and dicyclopentadiene dioxide.
2,4,6-Trimethylaniline led to cirrhosis of the liver in rats only."

from

Weisburger EK, Russfield AB, Homburger F, Weisburger JH, Boger E, Van
Dongen CG, Chu KC.

Testing of twenty-one environmental aromatic amines or derivatives for
long-term toxicity or carcinogenicity.

J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):325-56

> Benzoguanamine
 
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