I like Eckerd's Pharmacy Computer System.  It's the main reason that continue
to work there.  Each terminal has 3-4 different sessions that one can sign on
to in order to fill prescriptions.  Internet access is pretty reasonably
liberal-- we can search with Google-- and go to any pharmacy-business-related
site.  We also have access to Clinical Pharmacology 2000 online, which is a
decent reference.
It never seems to crash.  And, it only locks up if you press enter too many
times while adjusting the order.  But, there's a way to get it unlocked without
rebooting.
Entering a new prescription for an established patient is quite efficient with
this system as well...  you just tab & use function keys through one form for
most prescriptions & then use a function key to accept adjudication.  Filing a
prescription (or putting it on hold) is even easier.  And, once a prescription
is entered & adjudicated, you're done with the computer... no having to wait to
scan the presciption in.  no having to go back the computer to see what has or
hasn't been adjudicated.  no having to wait for the label with the bar code to
print out.  no having to scan the bar code so you can wait for the computer to
look up the prescription & show you what the drug should look like.  I can do a
very thorough check of the NDC on the bottle & the Rx label as well as a very
thorough check of the drug & patient name on an Rx label in the time it takes
to do all that scanning & waiting.  Is Eckerd the only chain that has this kind
of system?  I hope not.  But, from what I'm hearing, they might be.