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Medical Forum / General / Pharmacy / September 2003

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Drug interactions of Ezetimibe

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Chris Kernaghan - 19 Sep 2003 18:14 GMT
Hi guys,

Does anyone know of, or have experience of drug interactions which involve
Ciclosporin and Ezetimibe.

I currently have a relative who seems to be having a reaction to something.

He spikes a temperature and develops redness and inflammation,
predominantely in his legs, but this can spread to other areas.

He also has developed extreme photosensitivity, and intermittent nausea.

He has a past medical history of Cardiac transplant (1986)

Left Hip replacement (2003)

Basal Cell Carcinoma (1996)

He also has altered liver and kidney function due to prolonged use of
Ciclosporin (for this reason Statins are inappropriate.)

He also suffers from oedema in his ankles.

He currently is prescribed

1. Frumil (25mg mane)

2. Ciclosporin (175mg BD)

3. Asprin (75mg mane)

4. Ranidine (150mg mane)

5. Ezetimibe (10mg OD (Lunchtime))

6. Minocin (100mg mane)

7. Allopurinal (200mg OD (Lunchtime))

8. Colchicine 500mcg PRN

9. Laculose 5ml BD

Has anyone any experience of  any drug interactions with any of the drugs
listed above that would possibly cause the reactions described.

TIA

Chris Kernaghan
Larry Krzewinski - 19 Sep 2003 18:25 GMT
>Hi guys,
>
[quoted text clipped - 45 lines]
>
>Chris Kernaghan

Chris,
You can research the drug's side effects yourself here:

http://www.healthandage.com/html/res/com/ConsLookups/Drugs.html#letA

But you have to know the correct spelling of the drugs.  Many of the
ones that you listed are misspelled making it hard to answer your
question.

Larry

Reply to larrykz at charter dot net.
- 19 Sep 2003 23:58 GMT
In June 2003, Schering-Plough altered the label for Zetia to
include a warning that it may be associated with allergic
reactions, including angioedema, a skin disease
characterized by patches of circumscribed swelling of the
hands, feet, lips and eyelids. Patients suffering from
angioedema often experience swelling of the mucous membranes
and the viscera (internal organs of the body). Breathing is
sometimes difficult, and in severe cases the disease can be
fatal. Rash has also been linked to Zetia use.

> >Hi guys,
> >
[quoted text clipped - 48 lines]
> Chris,
> You can research the drug's side effects yourself here:

http://www.healthandage.com/html/res/com/ConsLookups/Drugs.h
tml#letA

> But you have to know the correct spelling of the drugs.  Many of the
> ones that you listed are misspelled making it hard to answer your
[quoted text clipped - 3 lines]
>
> Reply to larrykz at charter dot net.
 
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