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Medical Forum / General / Pharmacy / February 2005Non-extended-release Prilosec
I've been taking OTC Prilosec (10mg), which is an extended-release tablet. Since my doctor suggested increasing it to 20mg, I figured it would be more cost effective to get a prescription, so she wrote one for the generic version. The generic version (20mg) seems to be an ordinary capsule, not an extended-release tablet. Would this be less effective? Would it last all day anyway? Might I be better off taking two 10mg tablets (or capsules) 12hr apart? Is it typical to take 20mg all at once? I'll mostly likely take it in the morning. Thanks OTC Prilosec is 20 mg in the US > I've been taking OTC Prilosec (10mg), which is an extended-release > tablet. Since my doctor suggested increasing it to 20mg, I figured it [quoted text clipped - 8 lines] > > Thanks Oops! I wonder why I got it into my head that it was 10mg. I guess I'm not increasing my dosage, just saving money. Still, I wonder if the non-extended-release is better/worse/makes no difference... Is it some other dosage in other countries? > Oops! I wonder why I got it into my head that it was 10mg. I guess I'm > not increasing my dosage, just saving money. Still, I wonder if the > non-extended-release is better/worse/makes no difference... > > Is it some other dosage in other countries? The prescription TR capsules came in both 10 and 20 mg dosages. The OTC form is delayed release. Read the package under where is says PRILOSEC where it says omeprazole delayed-release tablets. OTC > I've been taking OTC Prilosec (10mg), which is an extended-release > tablet. Since my doctor suggested increasing it to 20mg, I figured it [quoted text clipped - 3 lines] > The generic version (20mg) seems to be an ordinary capsule, not an > extended-release tablet. This is confused. The OTC form of Prilosec is in a delayed release tablet and the prescription form in a capsule with time release granules. If you want generic omeprazole, you'll have to get from Mexico. The stuff sold in the States is made by or for the same drug company that offered the prescription form as I recall. OTC Prilosec is a different salt of omeprazole than the prescription form of the drug. The former is a sodium salt and the latter is a magnesium salt as I recall. The drug book doesn't say.....hmmm. > Would this be less effective? Would it last > all day anyway? Might I be better off taking two 10mg tablets (or > capsules) 12hr apart? Is it typical to take 20mg all at once? I'll > mostly likely take it in the morning. > > Thanks Maybe I was confused, but what I have now says (on the Rx label): IC OMEPRAZOLE 20MG CAPSULE DRMYL MYLAN SUBSTITUTED FOR PRILOSEC The capsules are blue and green and say MYLAN 6150 on them. This I got from CVS here on the USA. What I had before was the Prilosec OTC in the purplish box. > Maybe I was confused, but what I have now says (on the Rx label): > [quoted text clipped - 7 lines] > > What I had before was the Prilosec OTC in the purplish box. DR stands for delayed release. MYL must just stand for Mylan. You do have generic omeprazole. And I had the salts reversed. The magnesium form is the OTC form and the sodium form the prescription form. > I've been taking OTC Prilosec (10mg), which is an extended-release > tablet. Since my doctor suggested increasing it to 20mg, I figured it [quoted text clipped - 8 lines] > > Thanks In my humble NONPROFESSIONAL and casual opinion, much of the motivation behind slow release formulations is to get additional patent protection status. If the regular formulation works, it is probably good enough. Much as its professional practitioners may claim otherwise, Medicine IS an engineering-like art. If it works, that is fine, but if it does not, then the results can be disasterous in the same way a collapsing bridge can be. Bill Bill No matter what the release, Prilosec will work for 24 hours (supposedly-it varies from patient to patient) because it works by deactivating the acid producer in your stomach and your body takes 24 hours to make new acid producers to replace the ones deactivated ((in simple terms). Same with Nexium, Protonix and the whole class of drugs, all 24 hours. |
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