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Medical Forum / General / Pharmacy / August 2004Ritalin v.s. Wellbutrin
What is the difference between Ritaline and Wellbutrin? I understand both block dopamine reuptake but neither actually produces dopamine?? tslf > What is the difference between Ritaline and Wellbutrin? I understand > both block dopamine reuptake but neither actually produces dopamine?? > > tslf Surely if dopamine is present and the drug's presence is there to prevent reuptake then the existing dopamine can do it's work? Same principle as SSRI's for example? Graham 1943 tslf wrote: > > What is the difference between Ritaline and Wellbutrin? I understand > > both block dopamine reuptake but neither actually produces dopamine?? Neither produces dopamine, and neither blocks dopamine reuptake. Cocaine does this. Ritalin (methylphenidate) releases dopamin the same way other amphetamines do. The method of action regarding ADD/ADHD is releasing dopamine which enables the patient to concentrate on the problems at hand. A person with ADD/ADHD usually has lower levels of dopamine present in the bloodstream than a normal person. Mehtylphenidate handles this pretty well. Wellbutrin (bupropion) is not an amphetamine like methylphenidate, and the mechanism of action is still uncertain. It is believed that the drug increases noradrenaline release. This drug has no effect on dopamine uptake (or other amines, for that matter). Hope this helps you. Asger I may have misread this article, but it states it prevent dopamine uptake?? http://pharma-help.com/wellbutrin It works by inhibiting the reuptake of the neurotransmitters dopamine, serotonin, and norepinephrine, resulting in more of these chemicals being available to transmit messages to other nerves. Bupropion is unique in that its major effect is on dopamine. > tslf wrote: > > > What is the difference between Ritaline and Wellbutrin? I understand [quoted text clipped - 15 lines] > > Asger |
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