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Medical Forum / General / Nutrition / March 2008

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Calcium supplements: with or without vitamin D?

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Charles Packer - 18 Mar 2008 11:25 GMT
We take calcium supplements because we don't drink milk.
My wife says we should buy only the ones that include
vitamin D because it _must_ be taken along with the
calcium for optimal absorption. I say: not necessary,
because we have vitamin D in our multivitamin and from
sunlight exposure, and as long as we have this background
level in our systems, that's good enough.

I found one thread from a several years ago where a
self-described nutritionist took my point of view. We need
something more authoritative. Can anybody point me to a
relevant medical Web site? I gave up pursuing the matter
in these newsgroups because I discovered you really go
down the rabbit hole tracking discussions of calcium
metabolism.

--
Charles Packer
http://cpacker.org/whatnews
mailboxATcpacker.org
Ron Peterson - 18 Mar 2008 16:46 GMT
> We take calcium supplements because we don't drink milk.
> My wife says we should buy only the ones that include
[quoted text clipped - 3 lines]
> sunlight exposure, and as long as we have this background
> level in our systems, that's good enough.

See http://thevitamindcure.com/ -- the author was on the People's
Pharmacy talk show the other week and seemed convincing but a little
over enthusiastic.

Vitamin D doesn't need to be taken at the same time as the calcium. In
addition, the amount of vitamin D included in multivitamins and
calcium supplements may be inadequate. You can get enough vitamin D
from sun exposure in the summer time, but that increases your risk for
skin cancer. The supplements are inexpensive and safe, so just take
one of those. My SO and I take 2400 IU/day.

Vitamin K is also important for preventing osteoporosis, but it's not
clear how much of what type is enough.

> I found one thread from a several years ago where a
> self-described nutritionist took my point of view. We need
[quoted text clipped - 3 lines]
> down the rabbit hole tracking discussions of calcium
> metabolism.

http://photomed.de/fileadmin/download/Werbemittel/holick-review.pdf is
a start.

You can Google other papers, but be sure to used advanced search and
use Google Scholar.

--
  Ron
Marshall Price - 21 Mar 2008 05:55 GMT
> We take calcium supplements because we don't drink milk.
> My wife says we should buy only the ones that include
[quoted text clipped - 16 lines]
> http://cpacker.org/whatnews
> mailboxATcpacker.org

There are concerns nowadays that the DV for vitamin D may not be high
enough (considering that taking 1,000 IU a day seems to have
cancer-preventive value), but as for taking it concurrently with
calcium, the very fact that it's a fat-soluble vitamin implies that
(unlike many water-soluble vitamins) it can be accumulated in the body
and therefore need not be taken very often.

Charlie Rose has been hosting a series of specials in which very highly
respected scientists come together to discuss the state of their arts,
including medicine, and recently they discussed the hypothesis that both
folic acid and vitamin D help prevent cancer (one by repairing
chromosome damage, if I recall correctly), and that the DVs of both
ought to be increased.

Signature

Marshall Price of Miami
Known to Yahoo as d021317c

trigonometry1972@gmail.com | - 22 Mar 2008 10:48 GMT
> > We take calcium supplements because we don't drink milk.
> > My wife says we should buy only the ones that include
[quoted text clipped - 23 lines]
> (unlike many water-soluble vitamins) it can be accumulated in the body
> and therefore need not be taken very often.

It depends. The off repeated saw about fat soluble vitamin and long
term s is a
deeply flawed generalization. In the case of vitamin D, as it comes in
two forms D2 and D3 and most people only take tiny doses at most.
Anyway the plant sterol form when given in large oral bolus doses
will raise the serum 25 OH vit D levels for a couple of weeks and then
the levels will
tned to drop below preadminsteration levels. Only regular doses
of D2 can maintain increases to 25 OH vit D levels. Whereas, vitamin
D3 bolus doses are more effective in maintaining increases in
vitamin D. There is evidence that the the RDA in the fall and winter
should be 4000 IU for adults and 6000 for lacating women.

As to folic acid it may take a full milligram to attain optimal serum
quality and .7 or .8 milligrams to maintain genomic stability.
I would suggest additional cobalamin in the context of increased
folic acid levels. Moreover, additional betaine may also
have its mertis alone and with the folic acid and B-12.

> Charlie Rose has been hosting a series of specials in which very highly
> respected scientists come together to discuss the state of their arts,
[quoted text clipped - 6 lines]
> Marshall Price of Miami
> Known to Yahoo as d021317c
Marshall Price - 22 Mar 2008 20:19 GMT
>>> We take calcium supplements because we don't drink milk.
>>> My wife says we should buy only the ones that include
[quoted text clipped - 46 lines]
>> chromosome damage, if I recall correctly), and that the DVs of both
>> ought to be increased.

I never took betaine seriously.  Can you point me to some reliable
information on it?

Signature

Marshall Price of Miami
Known to Yahoo as d021317c

trigonometry1972@gmail.com | - 22 Mar 2008 22:58 GMT
> On Mar 22, 11:19 am, Marshall Price <d0213...@yahoo.com> wrote:
> I never took betaine seriously.  Can you point me to some reliable
[quoted text clipped - 3 lines]
> Marshall Price of Miami
> Known to Yahoo as d021317c

The folder on the topic primarily has the bulky  PDF files
so instead I'll suggest some PUBMED searches with
the following search words in combination with betaine or
trimethylglycine: homocysteine, s-adenosylmethionine,
methyl, alcohol, steatosis, SAMe, methylation, equimolar,
redox status, thiol, glutathione, nuclear factor-kb, aging,
niacin. There are many lines of evidence for it value.

Personally I pretty wedded to betaine HCL as a digestive
aid which I find to be profoundly helpful. Therefore, I getting
a multi-gram dose of the betaine base.
Marshall Price - 23 Mar 2008 11:55 GMT
>> On Mar 22, 11:19 am, Marshall Price <d0213...@yahoo.com> wrote:
>> I never took betaine seriously.  Can you point me to some reliable
[quoted text clipped - 11 lines]
> aid which I find to be profoundly helpful. Therefore, I getting
> a multi-gram dose of the betaine base.

Okay.  Thanks.  I'm already into SAM for spermine and spermidine synthesis.

(I had digestive trouble before I fasted, but no trace of it afterwards.
 Certainly no steatosis.  Before, when I slapped my belly, I could
often tell there was gas inside.  That's one of the many things that
disappeared completely.  I just wonder whether fasting is as helpful for
skinny people as it is for chubby ones.  As I've said before, I'm going
to try it again sometime soon, though my weight now is 120 lbs and my
waist is 30 inches.)

Signature

Marshall Price of Miami
Known to Yahoo as d021317c

trigonometry1972@gmail.com | - 23 Mar 2008 23:50 GMT
> trigonometry1...@gmail.com | wrote:
> >> On Mar 22, 11:19 am, Marshall Price <d0213...@yahoo.com> wrote:
[quoted text clipped - 26 lines]
> Marshall Price of Miami
> Known to Yahoo as d021317c

Hopefully, you aren't six feet tall as at 120 pounds you'd be
underweight.

I think on first blush that the cubby, the obese, an the
overweight would most benefit from fasting. Though on the other hand,
a person who is melting off the fat, will likely be faced with the
release
of a heavy load of stored fat soluble toxins such as DDE
and so on.

What folic acid is good for, so is betaine. And betaine can work by
way
of a separate biochemical pathway.

Soda pop drinkers are said to often have a fatty liver...steatosis of
the liver.
Marshall Price - 24 Mar 2008 21:39 GMT
>> trigonometry1...@gmail.com | wrote:
>>>> On Mar 22, 11:19 am, Marshall Price <d0213...@yahoo.com> wrote:
[quoted text clipped - 26 lines]
> Hopefully, you aren't six feet tall as at 120 pounds you'd be
> underweight.

No, five seven and a half, and not muscular.  I've still got fat to
burn.  :-)

> I think on first blush that the cubby, the obese, an the
> overweight would most benefit from fasting. Though on the other hand,
> a person who is melting off the fat, will likely be faced with the
> release
> of a heavy load of stored fat soluble toxins such as DDE
> and so on.

I was concerned about that, and did take vitamins and occasionally, a
few supplements.  But I figured if there were toxins in my adipose
tissue, it was high time I came to grips with them!  That's one of the
reasons I want to fast again, along with a hunch that I might be able to
shrink my colon, veins, and skin.

> What folic acid is good for, so is betaine. And betaine can work by
> way
> of a separate biochemical pathway.

Apparently, it plays a role in converting methionine-derived
homocysteine back into methionine, and in a couple reactions of lesser
importance.  But I suspect I can make all I need from folic acid.

> Soda pop drinkers are said to often have a fatty liver...steatosis of
> the liver.

I doubt I have that problem, especially after having burned off so much
body fat.  When I saw the word, I was thinking of intestinal steatosis
and suspected you might have meant steatorrhea, but they, too, don't
concern me.

Signature

Marshall Price of Miami
Known to Yahoo as d021317c


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