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Medical Forum / General / Nutrition / April 2008

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Low Globulin Level

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JayDee - 12 Mar 2008 21:56 GMT
Hi . I just got my blood test back and found that my globulin is 2.0
(range 2.1-3.7, but I've read other places that claim it should be
2.5-3.5). The Albumin/Globulin range was 2.5 (range 1.0-2.1).

The rest of my blood test was normal.

Any thoughts?

Thanks!

- JayDee
Marshall Price - 23 Mar 2008 16:20 GMT
> Hi . I just got my blood test back and found that my globulin is 2.0
> (range 2.1-3.7, but I've read other places that claim it should be
[quoted text clipped - 7 lines]
>
> - JayDee

It depends on the lab.  Each lab publishes its own set of normal ranges.
 (I've got a couple booklets around somewhere, but not close at hand.)

About five or ten years ago, there was a doctor on the public TV
stations during pledge-drive time who said that gamma-globulin levels
from initial blood tests taken at the time of admission to hospitals
were a good indicator of mortality.  The higher a patient's initial
gamma-globulin level, the greater the likelihood he'd live.

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Marshall Price of Miami
Known to Yahoo as d021317c

JayDee - 31 Mar 2008 18:09 GMT
> > Hi . I just got my blood test back and found that my globulin is 2.0
> > (range 2.1-3.7, but I've read other places that claim it should be
[quoted text clipped - 20 lines]
> Marshall Price of Miami
> Known to Yahoo as d021317c

oh boy... that's not very encouraging.

So does anyone know what causes this and if there's anything one can
do to raise their globulin levels? The doc told me it was nothing to
worry about and sometimes these results aren't the most accurate when
done by the lab I went to (Quest diagnostics), but if there's anything
I can do to improve this number, please let me know!

Thanks.

- JayDee
Marshall Price - 01 Apr 2008 16:09 GMT
>>> Hi . I just got my blood test back and found that my globulin is 2.0
>>> (range 2.1-3.7, but I've read other places that claim it should be
[quoted text clipped - 27 lines]
>
> - JayDee

Sorry, I forget who the doctor was, and I'm not familiar with the
subject.  For what it's worth, I'm pretty sure it wasn't Covert Bailey,
Andrew Weil, or Nicholas Perricone.

Incidentally, /The Merck Manual 16/ contains an extensive list of
laboratory normal ranges in its "Special Subjects" section.  They're the
ones used at the Massachusetts General Hospital and published in NEJM.

Here's an excerpt:

 Determination         Reference Range

 Protein: Total        6.0-8.4 gm/dL
   Albumin             3.5-5.0 gm/dL
   Globulin            2.3-3.5 gm/dL
       Note: Globulin equals total protein minus albumin.
   Electrophoresis     % of total protein
       Note: Quantitation by densitometry
     Albumin           52-68
     Globulin:
      alpha-1          4.2-7.2
      alpha-2          6.8-12
      beta             9.3-15
      gamma            13-23

I wouldn't give it a second thought, frankly.  Perhaps you could find
out how variable it usually is from hour to hour, assuming it depends on
meals, exercise, sleep, growth, etc., but why distrust your doctor?

To me, the surprising thing is that it's the only measurement that was
out of range.  Of ten independent tests, assuming the normal range is
from the 5th to the 95th percentiles, you'd expect one to be out of
range anyway, if I understand the math, and it was very close.

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Marshall Price of Miami
Known to Yahoo as d021317c

Mr-Natural-Health - 01 Apr 2008 16:56 GMT
> Hi . I just got my blood test back and found that my globulin is 2.0
> (range 2.1-3.7, but I've read other places that claim it should be
[quoted text clipped - 3 lines]
>
> Any thoughts?

You are posting in the wrong newsgroup.

Try news:sci.med.laboratory
http://groups.google.com/group/sci.med.laboratory/topics
 
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