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Medical Forum / General / Nutrition / December 2007

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Gotu Kola and Skin Cancer???

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JayDee - 26 Dec 2007 23:20 GMT
Originally, I wanted to take this herb for its touted benefits for
concentration, etc but after researching, I came across some pretty
scary warnings - I included  bits from a couple of these below. In
light of these studies, I'm wondering why anyone would take it -
especially the combination of potential skin cancers combined with
studies that show it has the possibility of increaseing tumor size...
sounds like a horrifying combination!

I'm curious what you all think of these studies, and if they also
relate to Brahmi monniera - the cousin of Gotu Kola...

Article excerpts:

http://www.organicindia.com/gotu-kola.php

1) Gotu Kola should not be used for long periods as continued use
could result in skin conditions such as lesions, or even skin cancers
(melanoma). It may also cause dizziness, upset stomach, and even
drowsiness if used in excessive doses. It is not recommended to be
taken along with sleep inducing medications such as sedatives.

Another site: (http://www.healthandage.com/html/res/com/ConsHerbs/
GotuKolach.html) stated:

2) The use of gotu kola for more than 6 weeks is not recommended.
People taking the herb for an extended period of time (up to 6 weeks)
should take a 2-week break before taking the herb again.

Asiaticoside, a major component of gotu kola, has also been associated
with tumor growth in mice. Though more studies are needed, it is wise
for anyone with a history of precancerous or cancerous skin lesions--
such as squamous cell, basal cell skin cancer, or melanoma--to refrain
from taking this herb

Thanks!

- JayDee
Rodney Reid - 29 Dec 2007 01:03 GMT
Hi JayDee,

I've been taking Gotu Kola [Centella Asiatica] extract for about 12
years now (currently 39).   All in all, I've skipped about a year in
that time of taking it every day: 12% asiaticosides, 500mg-1000mg
daily of this brand - http://www.easycart.net/BeyondACenturyInc./Herbals_F-J.html#8055

What I'm seeing on pubmed says [thankfully, hopefully?] the opposite
of that.

Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells.
(Cancer Lett. 2005 Jan 31;218(1):81-90.)
http://www.ncbi.nlm.nih.gov/pubmed/15639343?ordinalpos=4&itool=EntrezSystem2.PEn
trez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

"...These results further suggest that AA may be a good candidate for
the therapeutic intervention of human skin cancer."

There are other articles purporting anti-cancer effect of Gotu Kola, I
typed in:

Centella Asiatica AND cancer
at: http://www.ncbi.nlm.nih.gov/sites/entrez

Have a great 2008,

...Rodney

> Originally, I wanted to take this herb for its touted benefits for
> concentration, etc but after researching, I came across some pretty
[quoted text clipped - 33 lines]
>
> - JayDee
 
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