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Medical Forum / General / Nutrition / June 2007

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Canadian Cancer Society- "take vitamin D'

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bigvince - 12 Jun 2007 01:49 GMT
>From  " Sweeping cancer edict: take vitamin D daily "; Globe and
Mail,  7/8/07  "
http://www.theglobeandmail.com/servlet/story/RTGAM.20070608.wvitaminD08/BNStory/
specialScienceandHealth/home

TORONTO - The Canadian Cancer Society plans to announce Friday that
all adults should start taking vitamin D, coinciding with the release
of a groundbreaking U.S. study indicating the supplement cuts the risk
of cancer by an astounding 60 per cent.
The move is believed to be the first time a major public-health
organization has endorsed daily use of the sunshine vitamin as a
cancer-prevention therapy for an entire population.

It follows a flurry of research suggesting the low-cost vitamin
confers a high degree of protection against a wide variety of cancers.
There are also striking study results suggesting that people who
develop the disease often have low blood levels of vitamin D.

Although it is not known how many of the approximately 160,000 cancer
cases diagnosed annually in Canada might be avoided by regular popping
of a vitamin D pill, the cancer society said these findings are so
compelling it felt it had to start urging people to act on
them......full story at link .         The guestion is why has the
American Canser Society not followed suit
cleanskin@itspuresoap.com - 14 Jun 2007 20:12 GMT
even better... everyone needs to take Cod Liver Oil!

Tom
www.itspuresoap.com

> >From  " Sweeping cancer edict: take vitamin D daily "; Globe and
> Mail,  7/8/07  "
[quoted text clipped - 18 lines]
> them......full story at link .         The guestion is why has the
> American Canser Society not followed suit
TC - 15 Jun 2007 20:32 GMT
> >From  " Sweeping cancer edict: take vitamin D daily "; Globe and
>
[quoted text clipped - 18 lines]
> them......full story at link .         The guestion is why has the
> American Canser Society not followed suit

Oncologists won't like that. They'll lose income.
WaCoder - 16 Jun 2007 13:39 GMT
>> >From  " Sweeping cancer edict: take vitamin D daily "; Globe and

big snip

> Oncologists won't like that. They'll lose income.

So will big pharma and all the politicos out there. :(
Gee, I'm really crying for them now....not.
Juhana Harju - 25 Jun 2007 09:02 GMT
>> From  " Sweeping cancer edict: take vitamin D daily "; Globe and
> Mail,  7/8/07  "
[quoted text clipped - 17 lines]
> compelling it felt it had to start urging people to act on
> them......full story at link .

Canadian Cancer Society Announces Vitamin D Recommendation
08 June 2007

TORONTO - The Canadian Cancer Society is recommending a specific amount of
Vitamin D supplementation for Canadians to consider taking. This first-time
recommendation is based on the growing body of evidence about the link
between Vitamin D and reducing risk for colorectal, breast and prostate
cancers.

"The evidence is still growing in this area, but we want to give guidance to
Canadians about this emerging area of cancer prevention based on what we
know now," says Heather Logan, Director, Cancer Control Policy, Canadian
Cancer Society. "As we find out more we will update our recommendation."

In consultation with their healthcare provider, the Society is recommending
that:

Adults living in Canada should consider taking Vitamin D supplementation of
1,000 international units (IU) [25 micrograms] a day during the fall and
winter.

Read the full article:
http://tinyurl.com/2h2jes

Signature

Juhana

Ron Peterson - 25 Jun 2007 20:48 GMT
> Adults living in Canada should consider taking Vitamin D supplementation of
> 1,000 international units (IU) [25 micrograms] a day during the fall and
> winter.

> Read the full article:http://tinyurl.com/2h2jes

And, a doctor also recommends 1,000 IU vitamin D in
http://www.wpr.org/zorba/article_vitamind.htm
saying:
"VITAMIN D "FAQ"

Does Vitamin D prevent Cancer?

Perhaps. Here's the data.  More than 1000 women in Nebraska, not noted
for it's sun soaked atmosphere took Calcium or Calcium with Vitamin D,
or a placebo for 4 years.  They looked at cancer statistics -- none
had cancer when the study started -- and found that 12 months after
the study started (to weed out anyone whose cancer might have been in
the body, but not detected at the beginning of the study) there was
more than a 75% reduction in cancer risk with those taking Vitamin D
vs. those taking calcium only or a placebo.

What type of Vitamin D should I be looking for?

Vitamin D3 was what was studied.

How much should I take each day?

I would recommend 1000 IU (international units) of D3. A bottle of 100
cost about $7 or $8.

Can I get Vitamin D through natural sources (i.e. sun, food)?

You can get it from the sun, but it's very hard to get enough unless
you live in the sun and play in the sun. And too much time in the sun
can increase risk for skin cancer. It's best to get it through
supplements. As far as food: Dairy products are your best bet. Here's
a helpful guide I like to use."

--
 Ron
Matti Narkia - 25 Jun 2007 21:28 GMT
>How much should I take each day?
>
[quoted text clipped - 7 lines]
>can increase risk for skin cancer. It's best to get it through
>supplements. As far as food: Dairy products are your best bet.

Wild fish is by far the best source of vitamin D, dairy products
(except possibly vitamin D fortified dry milk _powder_) don't come
even close.

Signature

Matti Narkia

swabymanor@googlemail.com - 26 Jun 2007 00:23 GMT
Your body uses 4000iu daily
http://www.ajcn.org/cgi/content/full/77/1/204

To obtain adequate Vitamin D status to ensure all your body's needs
for Vitamin D can be adequately met requires 100nmol/L
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17218096
Circulating Vitamin D3 and 25-hydroxyvitamin D in Humans: An Important
Tool to Define Adequate Nutritional Vitamin D Status

http://www.ajcn.org/cgi/content/full/85/3/649
The urgent need to recommend an intake of vitamin D that is effective
Tells us that Supplemental intake of 400 IU vitamin D/d has only a
modest effect on blood concentrations of 25(OH)D, raising them by 7-12
nmol/L,
Thus to maintain a status of 1000nmol/L requires @4000iu/d

Risk assessment for vitamin D http://www.ajcn.org/cgi/content/abstract/85/1/6
shows that 10,000iu/d is a safe upper limit providing a huge safety
margin as 40,000iu/d is the level which after many months will produce
actual(but remediable) harm.

Anyone who thinks dietary sources of vitamin D are or could be
adequate is simply displaying their level of ignorance.

http://blog.myspace.com/index.cfm?fuseaction=blog.ListAll&friendID=199605272&MyT
oken=950a6edf-0890-468b-ac86-4a6396844581ML

I've blogged on the way Sunlight may be needed to prime T cells to
function in skin
You have to get your risk factors into perspective. There is plenty of
evidence around to show that for each individual who dies from
excessive sun exposure causing sunburn and subsequently skin cancer
over 30 people will die from cancers that thrive in Vitamin D
insufficient bodies. Now why do we think it is right to sacrifice 30
people in order to save one pillock who persists in sunbathing while
their skin is burning. That is only the tip of the iceberg. For that
idiot who cannot be bothered to cover up or apply sunblock when their
skin starts to redden, over 600 people will die from conditions such
as heart disease, diabetes, obesity osteoporosis, osteoarthritis and
the many many other chronic conditions which thrive in vitamin
depleted bodies.

I just don't understand why people refuse to recognise we are living/
dieing through a Vitamin d deficiency epidemic
http://www.ajcn.org/cgi/content/abstract/85/3/860
Matti Narkia - 26 Jun 2007 09:30 GMT
>Your body uses 4000iu daily
>http://www.ajcn.org/cgi/content/full/77/1/204
[quoted text clipped - 19 lines]
>Anyone who thinks dietary sources of vitamin D are or could be
>adequate is simply displaying their level of ignorance.

You are preaching to the choir. I've stressed here and elsewhere the
importance of using vitamin D supplements since 1999. I've also posted
all the studies you mentioned into this and other groups, some of them
numerous times. I've been taking at least 1000-2000 IU of vitamin D
supplements daily for the large part of the year since 1999,
increasing the dose to 4000-5000 IU over four years ago. But the
question here was about best dietary source of vitamin D, which is not
dairy products, but wild fish. And that's where your vitamin D
knowledege apparently needs some brush-up: According to
<http://www.nutritiondata.com/foods-000102000000000000000-w.html>
Atlantic herring contains 1628 IU of vitamin D /100 g and according to
<http://www.fineli.fi/topfoods.php?compid=2271&fuclass=all&specdiet=none&items=10
0&from=top&portion=100g&lang=en
>
whitefish contains 22 µg = 880 IU vitamin D per 100 g. So eating daily
200 g of Atlantic herring you would get 3256 IU and 200 g of whitefish
1760 IU of vitamin D per day. These amounts are not negligible and
could be sufficient for some people. Still, vitamin D content of fish
varies quite a bit and not many people are willing to eat fish daily.
Fish may also unfortunately contain some environmental pollutants,
which may force to restrict the consumption of at least some type of
fish. So I do agree that taking vitamin supplements is sensible and
have taken them myself since 1999 as I mentioned, but you are wrong if
you categorically state that dietary sources of vitamin D would always
be inadequate for all people.

Signature

Matti Narkia

swabymanor@googlemail.com - 26 Jun 2007 22:27 GMT
I'm sorry if I worded that somewhat dogmatically.
In the UK 70% of the population do not eat oily fish at all ever, Not
even an sardine.
Those that do eat oily fish eat only portion every 3 weeks on average.
So in the UK for all practical purposes it is reasonable to regard
dietary sources of Vitamin d as in the main trivial.
There are of course exceptions to every rule but I still think we
should focuss attention on acquiring vitamin D from safe sun exposure
were/when possible and the use of effective strength Vitamin D3
Cholecalciferol supplements.

Certainly for the average UK resident 1000iu/daily is not going to
raise status from below 75nmol/L to optimal 125nmol/L
http://www.ajcn.org/cgi/content/abstract/85/3/860 Hypovitaminosis D in
British adults at age 45 y:
Juhana Harju - 27 Jun 2007 06:58 GMT
> Certainly for the average UK resident 1000iu/daily is not going to
> raise status from below 75nmol/L to optimal 125nmol/L

Do you have references to back your claim that 125 nmol/l is optimal?

Signature

Juhana

Ron Peterson - 27 Jun 2007 15:33 GMT
> swabyma...@googlemail.com wrote:
> > Certainly for the average UK resident 1000iu/daily is not going to
> > raise status from below 75nmol/L to optimal 125nmol/L

> Do you have references to back your claim that 125 nmol/l is optimal?

125 nmol/l is considered to be the high end of normal.

Reinhold Vieth claims that >=100 nmol/l is needed to reduce
osteoporosis and hypertension.

--
  Ron
Juhana Harju - 27 Jun 2007 16:49 GMT
>> swabyma...@googlemail.com wrote:
>>> Certainly for the average UK resident 1000iu/daily is not going to
[quoted text clipped - 3 lines]
>
> 125 nmol/l is considered to be the high end of normal.

Yes, but is there any evidence that that level is associated with reduced
morbidity and mortality compared to 90-100 nmol/l? I have not seen that kind
of evidence.

> Reinhold Vieth claims that >=100 nmol/l is needed to reduce
> osteoporosis and hypertension.

Any reference?

Signature

Juhana

Ron Peterson - 27 Jun 2007 19:15 GMT
> >> Do you have references to back your claim that 125 nmol/l is optimal?

> > 125 nmol/l is considered to be the high end of normal.

> Yes, but is there any evidence that that level is associated with reduced
> morbidity and mortality compared to 90-100 nmol/l? I have not seen that kind
> of evidence.

Since Vieth claims >=100 nmol/l is the minimum needed, I am more
concerned whether the optimum > 125 nmol/l.

> > Reinhold Vieth claims that >=100 nmol/l is needed to reduce
> > osteoporosis and hypertension.

> Any reference?

I think I was looking at Vieth's survey at http://www.ajcn.org/cgi/content/full/69/5/842
.

--
  Ron
Juhana Harju - 27 Jun 2007 19:23 GMT
>>>> Do you have references to back your claim that 125 nmol/l is
>>>> optimal?
[quoted text clipped - 15 lines]
> I think I was looking at Vieth's survey at
> http://www.ajcn.org/cgi/content/full/69/5/842 .

That is quite an old study. I recall that Vieth has adopted a more moderate
position in his recent presentations.

Signature

Juhana

Ron Peterson - 27 Jun 2007 19:40 GMT
> > Since Vieth claims >=100 nmol/l is the minimum needed, I am more
> > concerned whether the optimum > 125 nmol/l.

> >>> Reinhold Vieth claims that >=100 nmol/l is needed to reduce
> >>> osteoporosis and hypertension.

> >> Any reference?

> > I think I was looking at Vieth's survey at
> >http://www.ajcn.org/cgi/content/full/69/5/842.

> That is quite an old study. I recall that Vieth has adopted a more moderate
> position in his recent presentations.

That may be I see his editorial in http://www.ajcn.org/cgi/content/full/85/3/649
says:
"Randomized trials using the currently recommended intakes of 400 IU
vitamin D/d have shown no appreciable reduction in fracture risk. In
contrast, trials using 700-800 IU vitamin D/d found less fracture
incidence, with and without supplemental calcium. The reduction in
fracture incidence occurs when mean serum 25(OH)D concentrations
exceed 72 nmol/L, and this change may result from both improved bone
health and reduction in falls due to greater muscle strength. Although
it is not yet proven through clinical trials, higher intakes may also
reduce the incidence of colon and other cancers, and these relations
indicate that the desirable 25(OH)D concentration is 75 nmol/L. One
recent report associates greater 25(OH)D concentrations with lower
risk of nursing home admission; the most desirable category of
concentration starts at 75 nmol/L."

Vieth references a July AJCN review article which says:
"Recent evidence suggests that vitamin D intakes above current
recommendations may be associated with better health outcomes.
However, optimal serum concentrations of 25-hydroxyvitamin D [25(OH)D]
have not been defined. This review summarizes evidence from studies
that evaluated thresholds for serum 25(OH)D concentrations in relation
to bone mineral density (BMD), lower-extremity function, dental
health, and risk of falls, fractures, and colorectal cancer. For all
endpoints, the most advantageous serum concentrations of 25(OH)D begin
at 75 nmol/L (30 ng/mL), and the best are between 90 and 100 nmol/L
(36-40 ng/mL). In most persons, these concentrations could not be
reached with the currently recommended intakes of 200 and 600 IU
vitamin D/d for younger and older adults, respectively. A comparison
of vitamin D intakes with achieved serum concentrations of 25(OH)D for
the purpose of estimating optimal intakes led us to suggest that, for
bone health in younger adults and all studied outcomes in older
adults, an increase in the currently recommended intake of vitamin D
is warranted. An intake for all adults of 1000 IU (40 ?g) vitamin D
(cholecalciferol)/d is needed to bring vitamin D concentrations in no
less than 50% of the population up to 75 nmol/L. The implications of
higher doses for the entire adult population should be addressed in
future studies."

--
  Ron
Juhana Harju - 27 Jun 2007 20:29 GMT
>>> Since Vieth claims >=100 nmol/l is the minimum needed, I am more
>>> concerned whether the optimum > 125 nmol/l.
[quoted text clipped - 48 lines]
> higher doses for the entire adult population should be addressed in
> future studies."

I am familiar with that study as I have posted it to this group. ;-)

Signature

Juhana

swabymanor@googlemail.com - 27 Jun 2007 20:33 GMT
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17218096

Circulating Vitamin D3 and 25-hydroxyvitamin D in Humans: An Important
Tool to Define Adequate Nutritional Vitamin D Status

This suggests that 100nmol/L should be regarded as the minimum level
and therefore 125nmol/L, as this is also associated with peak physical
performance, is a sensible level to aim for.
This is what Bruce Hollis says
http://www.esi-topics.com/nhp/2006/march-06-BruceWHollis.html
"It is maddening to me to hear physicians say "drink some milk and you
will obtain all the vitamin D you need." It is wrong and harmful to
the patient. No one should have a circulating 25(OH) D level-this is
the metabolite that defines nutritional vitamin D status-less than 80
nmol. I try to keep my own level at 125 nmol minimum and consume
between 2,000-8,000 IU/day depending on the season."
take note that he lives at Bruce W. Hollis, Ph.D. Professor of
Pediatrics  And Professor of Biochemistry & Molecular Biology
Director of Pediatric Nutritional Sciences
Medical University of South Carolina
Charleston, SC, USA

He's been publishing on Vit d for 30yrs and I suspect he knows more
than any of us. He's also using 6400iu/d with lactating mothers. It
was this research that threw up the finding that those mums on the
actual rathe than placebo had a 70% lower cold/flu incidence.
http://news.independent.co.uk/health/article2447662.ece
swabymanor@googlemail.com - 27 Jun 2007 20:25 GMT
> swabyma...@googlemail.com wrote:
> > Certainly for the average UK resident 1000iu/daily is not going to
[quoted text clipped - 4 lines]
> --
> Juhana

http://www.vitamindcouncil.com/
Enter "Optimal" in the search box.
Juhana Harju - 27 Jun 2007 20:33 GMT
>> swabyma...@googlemail.com wrote:
>>> Certainly for the average UK resident 1000iu/daily is not going to
[quoted text clipped - 4 lines]
> http://www.vitamindcouncil.com/
> Enter "Optimal" in the search box.

Well, I did the search and found the position Cannell has taken. I don't
think that that level is based on any outcomes.

Signature

Juhana

Juhana Harju - 25 Jun 2007 09:04 GMT
>> From  " Sweeping cancer edict: take vitamin D daily "; Globe and
> Mail,  7/8/07  "
[quoted text clipped - 17 lines]
> compelling it felt it had to start urging people to act on
> them......full story at link .

Canadian Cancer Society Announces Vitamin D Recommendation
08 June 2007

TORONTO - The Canadian Cancer Society is recommending a specific amount of
Vitamin D supplementation for Canadians to consider taking. This first-time
recommendation is based on the growing body of evidence about the link
between Vitamin D and reducing risk for colorectal, breast and prostate
cancers.

"The evidence is still growing in this area, but we want to give guidance to
Canadians about this emerging area of cancer prevention based on what we
know now," says Heather Logan, Director, Cancer Control Policy, Canadian
Cancer Society. "As we find out more we will update our recommendation."

In consultation with their healthcare provider, the Society is recommending
that:

Adults living in Canada should consider taking Vitamin D supplementation of
1,000 international units (IU) a day during the fall and winter.

Read the full article:
http://tinyurl.com/2h2jes

Signature

Juhana

 
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