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Medical Forum / General / Nutrition / December 2006

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Does too much protein in the diet increase cancer risk?

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coonskin@amestwp.com - 07 Dec 2006 14:32 GMT
This study looks at cancer risk by amount of protein consumed and the
total calories and exercise.  Amount of protein relates to amount of a
growth factor related to risk of cancer which is reflected in the 3
groups studied.  This raises questions about ratios of the 3 macro
nutrients and the sources and forms consumed of them.

http://mednews.wustl.edu/news/page/normal/8388.html?emailID=12304
TC - 07 Dec 2006 15:28 GMT
> This study looks at cancer risk by amount of protein consumed and the
> total calories and exercise.  Amount of protein relates to amount of a
[quoted text clipped - 3 lines]
>
> http://mednews.wustl.edu/news/page/normal/8388.html?emailID=12304

Actually it looks at small samples of people who are given very rough
dietary guidelines to follow and then measures levels of plasma growth
factors and certain hormones that *may* (or may not) indicate some risk
of cancers. That is about as small a study looking at as indirect
markers as I've seen in a long time. Hardly definitive. Very poor
science at best.

The authors are:

Fontana L, Klein S, Holloszy JO. Long-term low-protein, low-calorie
diet and endurance exercise modulat metabolic factors associated with
cancer risk. American Journal of Clinical Nutrition, vol. 84; pp.
1456-1462, December 2006.

Samuel Klein, M.D., Washington University School of Medicine.
Participated in a 9/96 meeting of gastroenterologists sponsored by
Procter & Gamble that resulted in a paper, Reg. Toxicol. Pharmacol.
26:210-218 (1997). Research support from ILSI (1988-89; $30,000); Ross
Laboratories (1991-94; $86,000); Sandias (1992-93; $12,000);
Alimentarics, Inc. (1996-97; $100,000) (from 1997 resum?)

***

Any involvement to ILSI makes this researcher very suspect as far as
being a real scientist and not just another salesman/marketer.

http://cspinet.org/integrity/nonprofits/international_life_sciences_institute.html

INTERNATIONAL LIFE SCIENCES INSTITUTE

Founded "in 1978 to work toward a safer, healthier world. ILSI is a
worldwide foundation that is making a difference in public health by
advancing the understanding of scientific issues related to nutrition,
food safety, toxicology, and the environment. ILSI is governed by an
Assembly of Members, which includes one representative from each of its
more than 400 member companies, and an elected Board of Trustees of
renowned scientists from academia and industry, all of whom volunteer
their time and expertise. ILSI members represent the world's leading
manufacturers of food and food ingredients, chemicals, pharmaceuticals,
and other consumer products." (http://www.ilsi.org/about/; September
22, 2000) ILSI has branches in about a dozen other countries/regions.

In 2006, the World Health Organization excluded ILSI from WHO
committees that set global standards for food and water supplies
because of links between ILSI membership and funding from the
commercial sector. (Clapp, Stephen. "ILSI excluded from WHO
standard-setting activities," Food Chemical News, 2/13/06).

ILSI has received funding from the alcoholic beverage industry.
(Addiction. 2001;96:197-202)

ILSI's fall, 1996, N.Y. Academy of Science conference on fat
substitutes was funded in part by Procter & Gamble (Mother Jones,
May/June, 1997, p.14).

Members of ILSI North America:

3M Microbiology
Ajinomoto U.S.A., Inc.
Archer Daniels Midland Company
BASF Corporation
Campbell Soup Company
Cargill, Incorporated
CNS, Inc.
The Coca-Cola Company
Colgate-Palmolive Company
ConAgra Foods
CTI Foods
Danisco USA, Inc.
DSM Nutritional Products Inc.
DuPont Haskell Laboratory
General Mills, Inc.
Gerber Products Company
GlaxoSmithKline Research
H.J. Heinz Company
Hershey Foods Corporation
International Flavors & Fragrances, Inc.
Johnson & Johnson
Kellogg Company
Kraft Foods, Inc.
Masterfoods USA
McCormick & Company, Inc.
McNeil Nutritionals
Mead Johnson Nutritionals
Monsanto Company
National Starch and Chemical Company
Nestl? USA, Inc.
Novozymes North America, Inc.
The NutraSweet Company
Nutrinova, Inc.
Ocean Spray Cranberries, Inc.
The Pepsi-Cola Company
Pfizer, Inc.
The Proctor & Gamble Company
Red Bull North America
Renessen LLC
Roche Vitamins, Inc.
Ross Products Division/Abbott Laboratories
Sethness Products Company
Tate & Lyle North America
Unilever Bestfoods North America
Wm. Wrigley Jr. Company
(http://www.ilsi.org/misc/NAassem.pdf; accessed 4/11/06)

*******

TC
coonskin@amestwp.com - 07 Dec 2006 16:17 GMT
"Actually it looks at small samples of people who are given very rough
dietary guidelines to follow and then measures levels of plasma growth
factors and certain hormones that *may* (or may not) indicate some risk
of cancers. That is about as small a study looking at as indirect
markers as I've seen in a long time. Hardly definitive. Very poor
science at best."

What, as experts in statistics say, would be the threshold for such
research?  Actually they were not given food guidelines, people who met
guidelines were found based on the food choices, exercise and calorie
intakes they were following for their own reasons.  As per usual you
don't pay attention to content except for headlines and not much more.

Note, "hypothesis-generating paper" was the main author's view of the
study, he, Fontana, was the principle author not the person you did the
"are you still beating your wife" hachet job on.  Here as all good
journals do these days is the funding information:

"Funding from the National Institute of Diabetes and Digestive and
Kidney Diseases and the National Center for Research Resources of the
National Institutes of Health supported this research."

As for your view about "good science" is, I fear even to mention it
gives far far more credence then this and past performance supports on
your part.
TC - 07 Dec 2006 19:06 GMT
> "Actually it looks at small samples of people who are given very rough
> dietary guidelines to follow and then measures levels of plasma growth
[quoted text clipped - 8 lines]
> intakes they were following for their own reasons.  As per usual you
> don't pay attention to content except for headlines and not much more.

More than a couple of dozen.

> Note, "hypothesis-generating paper" was the main author's view of the
> study, he, Fontana, was the principle author not the person you did the
> "are you still beating your wife" hachet job on.  Here as all good
> journals do these days is the funding information:

Let's see, a "hypothesis-generating paper" with tiny numbers of
subjects using inferences from other "hypothesis-generated" data on two
hypothesized possible markers for cancer risk. Sound like smoke based
on mirrors. Or mirrors based on smoke. Either way it is smoke and
mirrors.

> "Funding from the National Institute of Diabetes and Digestive and
> Kidney Diseases and the National Center for Research Resources of the
> National Institutes of Health supported this research."

Yep, the NIH's have a sparkling reputation for scientific independence.
Wait, no that is the FDA. No wait that is universities. No wait, hang
on there, they are all industry funded and industry inspired
organisations. Oh well. Nice try.

> As for your view about "good science" is, I fear even to mention it
> gives far far more credence then this and past performance supports on
> your part.

You can be well assured that when I present scientific studies here, I
will have vetted the authors and their organisations for industry
connections. Which is infinitely more than we can gather from your
cherry picking.

TC
coonskin@amestwp.com - 07 Dec 2006 19:59 GMT
"More than a couple of dozen."

So the basis for your quip about study size and your knowledge about
what size is required as a threshold is this?  More off the cuff
blather.

"Let's see, a "hypothesis-generating paper" with tiny numbers of
subjects using inferences from other "hypothesis-generated" data on two
hypothesized possible markers for cancer risk. Sound like smoke based on
mirrors. Or mirrors based on smoke. Either way it is smoke and mirrors."

No, we have already qualified you for how "expert" you are for "tiny"
study size, nada.  The rest sounds like the normal process of science
grinding out patterns from a broad spectrum of information.  But then
how would we expect you to know that?

"You can be well assured that when I present scientific studies here, I
will have vetted the authors and their organisations for industry
connections. Which is infinitely more than we can gather from your
cherry picking."

I doubt it.  Were all the price "studies" you like to hawk so vetted to
see who bankrolled them, I don't think so?  Imitation is quite
flattering, you now try to turn "cherry picking" back; as was first made
known to you as you parrot unvetted the price articles which are the
poster child for cherry picking information.

But such we can be quite assured is the theology of the lifestyle food
cults of all stripes.  And that theology is in contrast to the
suggestive results of the study at hand and is *THE* reason for your
reaction quite apart from any science at all.
TC - 07 Dec 2006 22:03 GMT
> "More than a couple of dozen."
>
[quoted text clipped - 27 lines]
> suggestive results of the study at hand and is *THE* reason for your
> reaction quite apart from any science at all.

Here is your chance to explain what a "lifestyle food cult" is.

TC
TC - 08 Dec 2006 15:11 GMT
> "More than a couple of dozen."
>
[quoted text clipped - 27 lines]
> suggestive results of the study at hand and is *THE* reason for your
> reaction quite apart from any science at all.

Here is your chance to explain what a "lifestyle food cult" is.

Chicken. Moron. Idiot. Industry lapdog.

TC
allr1@webtv.net - 09 Dec 2006 13:14 GMT
" Yep, the NIH's have a sparkling reputation for scientific
independence. Wait, no that is the FDA. No wait that is universities. No
wait, hang on there, they are all industry funded and industry inspired
organisations. Oh well. Nice try. "

^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^

You got that right!

It helps explain modern medicine's
track record too.

Just another MIC to worry about.
(M.edical I.ndustrial C.omplex)
TC - 09 Dec 2006 18:00 GMT
> " Yep, the NIH's have a sparkling reputation for scientific
> independence. Wait, no that is the FDA. No wait that is universities. No
[quoted text clipped - 10 lines]
> Just another MIC to worry about.
> (M.edical I.ndustrial C.omplex)

That is an interesting and very appropriate term to coin. MIC.

Notice that Coonie is always accusing me me being part of a lifestyle
food cult, yet he refuses to explain what he means by that. I don't
think he knows what it means, he just finds it convenient to use
terminology that implies some kind of illogical religious motivation to
those of us who are showing how poor the medical mainstreams science
is.

TC
 
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