I do great with it, but everybody is a little different...blame it on
that genome copy thang, ya' know...

Any chemical that is completely new to your body can have major and
sometimes negative effects when first taken at full strength (a more
normal dosage of PS is 100 mg).
This is why I always suggest to people that they start with about 1/8
of their target dosage and ramp up to the full dosage by doubling the
daily dosage every 2 weeks.

The two weeks gives you enough time to both ascertain the effects it is
having (both negative and positive) and for your body to get used to
the dosage. If the negative effects do not disappear by the end of the
two weeks then you should reduce the dosage until they disappear and
use that as you chronic dosage, only trying to increase every so often
if the positive effects appear to have disappeared.

Doctor's do not suggest ramping up medications in this manner only
because most of the time what they prescribe is needed urgently and
acutely for some pathology, so that the negative side effects are far
less important than stopping the pathology.

Unfortunately with softgels, spliting into a smaller dose is hard to
do. All that I can suggest is that you prick the softgel, take a little
out of it and keep the rest in the frig until taking the last of it,
before starting with another softgel.

Finally, PS is technically not a cholinergic chemical, since it
contains no choline. However, it does have positive effects on neuronal
membrane fluidity, as I recall.

--Paul Wakfer

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I don't know what your other medical conditions are or what other meds
you're on, but PS can lower your cortisol.  If you're already being
adrenally suppressed by anything else (medication or medical condition
or aging), PS could be lowering your cortisol to a less than desirable
level.

This is just one possibility among what I'm sure are many.

Susan

Same here.  Pro-cholinergic substances in general seem to aggravate
my dysthymia.  I've learned to avoid them.  Ironically, I too have a lousy
memory.

The soy based PS that you can buy is worthless. Matti has posted on this:

http://groups.google.com/group/sci.med.nutrition/msg/ea22dfeb5d4ab604

Your cloudy feeling had nothing to do with any cholinergic effect. It's
probably the weather.

Bob