Where you go are going wrong is to assume that arbitrary designations
of "calorie restricted" and "normal" diets are scientific constructs,
rather than sociological ones.  On my diet, I am naturally calorie
resticted - I don't have the desire or the need to eat more than
perhaps 1800 calories a day.  I do agree that once one is in such bad
physical shape as to be called a "diabetic," all bets are off, as they
say.  Obviously, it makes sense to attentuate oxidative and other
stressors, make sure your body is making enough stomach acid and
digestive enzymes, make sure your body is getting truly essential
vitamins and minerals (some of which are depleted rapidly during a lot
of oxidative stress), etc., but until someone does the kinds of
experiments I propose on real people (and not those that are on
"death's door"), I generally restrict myself to making suggestions
about maintaining health, not curing "diseases" that should have never
occurred in the first place (if our "experts" weren't the incompetents
they in fact are, for the most part).

http://www.westonaprice.org/basicnutrition/macronutrientland.html

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Stephen R. Spindler, professor of biochemistry at the University of
California at Riverside is the current guru of calorie restriction.
"Low-Calorie Diet Slows Aging in Mice in Study," claimed a recent
headline.17 According to the article, "Putting elderly mice on a very
low-calorie diet for as little as four weeks reversed many of the
changes in the activity of various genes that had occurred during
normal aging. . ." The resesearchers were not looking at actual signs
of disease, nor were they measuring lifespan, but instead focused on
the analysis of 11,000 different genes using a method called microarray
technology in which Spindler has large financial holdings.

Actually, none of these studies is particularly relevant to humans
eating real food because the rat and mice chow used is a highly
artificial concoction straight from Macro-Nutrient Land. The chow used
in Ross's rat studies consisted of 22 percent casein, 6 percent corn
oil and 59 percent sucrose! Thus, calorie restriction in these studies
means restriction of isolated protein (produced at high temperatures
that produce carcinogens), vegetable oil (invariably rancid) and
refined sugar (completely devoid of nutrients and a stress on any
living system). If this research has anything to teach us, it is that
the calories humans of every age should restrict are the empty calories
of white flour and sugar in processed foods; instead we are being
urged, over and over again, to cut back on fats.

unquote***