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Medical Forum / General / Nutrition / July 2006

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Steroids

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BigBeerBelly - 20 Jul 2006 13:00 GMT
Has anyone here used steroids?  What are the side effects?

I have been chatting to a guy that has suggested I try steroids as this

will help me get the type of body I want.  He said that he has some
mood swings with them but nothing else to worry about.

Should I give them a go?
Ron Peterson - 20 Jul 2006 15:08 GMT
> Has anyone here used steroids?  What are the side effects?

> I have been chatting to a guy that has suggested I try steroids as this
> will help me get the type of body I want.  He said that he has some
> mood swings with them but nothing else to worry about.

> Should I give them a go?

A coworker and a friend of his tried steroids while in the service. It
increased his physical strength considerably. He had the steroids under
medical supervision, so he wasn't overdosed as many are. When he went
off the steroids, his strength returned to normal. He said that the
steroids caused him to anger easily. He is weight lifter, but not a
body builder.

If you don't do weight lifting, the steroids won't help.

You should go to an endocrinolgist first to have your testosterone
levels checked and then the endocrinoligist can prescribe supplemental
testosterone or steroids. Testosterone doesn't have the muscle building
of steroids, but it will make you a little more lean.

Signature

  Ron

BigBeerBelly - 20 Jul 2006 15:12 GMT
Thanks Ron,

I'm a fat guy already, this bloke said that it would help me gain
more muscle definition and mass by just using them, no exercise was
needed.  So you can imagine that I am interested.

> > Has anyone here used steroids?  What are the side effects?
>
[quoted text clipped - 17 lines]
> testosterone or steroids. Testosterone doesn't have the muscle building
> of steroids, but it will make you a little more lean.
GMCarter - 20 Jul 2006 22:40 GMT
>Thanks Ron,
>
>I'm a fat guy already, this bloke said that it would help me gain
>more muscle definition and mass by just using them, no exercise was
>needed.  So you can imagine that I am interested.

Then your friend is misinformed. Anabolic steroids ONLY work in
conjunction with resistance exercise.

The BEST bet is to start a program of exercise that works best for
you. Avoid the drugs as they can have side effects and are costly.

        George M. Carter
Will Brink - 23 Jul 2006 16:22 GMT
> >Thanks Ron,
> >
[quoted text clipped - 4 lines]
> Then your friend is misinformed. Anabolic steroids ONLY work in
> conjunction with resistance exercise.

Sad to say, that's not actually true. Steroids with no exercise will
still work. In fact, one well known study found couch potatoes on T gain
more muscle then guys weight training without T. As expected, guys on T
who lifted weights had the most dramatic results. Though i would never
recommend such a stupid (read lazy) strategy of steroids and no
exercise, it will have some effects.

N Engl J Med. 1996 Jul 4;335(1):1-7.Click here to read  Links

   

   The effects of supraphysiologic doses of testosterone on muscle size
and strength in normal men.

   Department of Medicine, Charles R. Drew University of Medicine and
Science, Los Angeles, CA 90059, USA.

   BACKGROUND: Athletes often take androgenic steroids in an attempt to
increase their strength. The efficacy of these substances for this
purpose is unsubstantiated, however. METHODS: We randomly assigned 43
normal men to one of four groups: placebo with no exercise; testosterone
with no exercise; placebo plus exercise; and testosterone plus exercise.
The men received injections of 600 mg of testosterone enanthate or
placebo weekly for 10 weeks. The men in the exercise groups performed
standardized weight-lifting exercises three times weekly. Before and
after the treatment period, fat-free mass was determined by underwater
weighing, muscle size was measured by magnetic resonance imaging, and
the strength of the arms and legs was assessed by bench-press and
squatting exercises, respectively. RESULTS: Among the men in the
no-exercise groups, those given testosterone had greater increases than
those given placebo in muscle size in their arms (mean [+/-SE] change in
triceps area, 424 +/- 104 vs. -81 +/- 109 square millimeters; P < 0.05)
and legs (change in quadriceps area, 607 +/- 123 vs. -131 +/- 111 square
millimeters; P < 0.05) and greater increases in strength in the
bench-press (9 +/- 4 vs. -1 +/- 1 kg, P < 0.05) and squatting exercises
(16 +/- 4 vs. 3 +/- 1 kg, P < 0.05). The men assigned to testosterone
and exercise had greater increases in fat-free mass (6.1 +/- 0.6 kg) and
muscle size (triceps area, 501 +/- 104 square millimeters; quadriceps
area, 1174 +/- 91 square millimeters) than those assigned to either
no-exercise group, and greater increases in muscle strength (bench-press
strength, 22 +/- 2 kg; squatting-exercise capacity, 38 +/- 4 kg) than
either no-exercise group. Neither mood nor behavior was altered in any
group. CONCLUSIONS: Supraphysiologic doses of testosterone, especially
when combined with strength training, increase fat-free mass and muscle
size and strength in normal men.

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Will Brink @ www.BrinkZone.com

Curt James - 23 Jul 2006 18:09 GMT
T use? T for Than!

[...]

> <snip>Steroids with no exercise will still work. In fact, one
> well known study found couch potatoes on T gain more muscle
> then guys weight training without T.
^^^^^^^^^

Than.

Whenever you're comparing two groups or items it's thAn.

Example: Couch potatoes versus fitness trainers - "The couch potatoes
using T gained more musle thAn the fitness trainers.

As a factor of time it's thEn.

Example: When Will Brink uses that word correctly thEn hell will
certainly have frozen over!

> As expected, guys on T who lifted weights had the most
> dramatic results. Though i would never recommend such a
> stupid (read lazy) strategy of steroids and no exercise, it
> will have some effects.
>
>  N Engl J Med. 1996 Jul 4;335(1):1-7.<snip>

Interesting post regardless of the misuse, however.

Signature

Curt

GMCarter - 24 Jul 2006 12:11 GMT
snip
>> Then your friend is misinformed. Anabolic steroids ONLY work in
>> conjunction with resistance exercise.
>
>Sad to say, that's not actually true. Steroids with no exercise will
>still work.

Thanks for the study--the abstract is confusing (and a little peculiar
that men in the placebo group had a LOSS of tissue?) I'd like to read
the whole article.

At that dose (pretty high) you'll probably get something but if one
continued on for more than 10 weeks, other issues would probably
arise.

So I think the study supports the idea that steroids alone could make
some changes--and if a person wants to try it, they can do whatever
they want.

But then some people think Bush is smart and Scientology is a
religion!

        George M. Carter

>In fact, one well known study found couch potatoes on T gain
>more muscle then guys weight training without T. As expected, guys on T
[quoted text clipped - 40 lines]
>when combined with strength training, increase fat-free mass and muscle
>size and strength in normal men.
Will Brink - 25 Jul 2006 14:24 GMT
> snip
> >> Then your friend is misinformed. Anabolic steroids ONLY work in
[quoted text clipped - 6 lines]
> that men in the placebo group had a LOSS of tissue?) I'd like to read
> the whole article.

It's worth reading. Sure, if they increased energy use without
additional cals, tissue loss would be the result. I am just speculating
there BTW.

> At that dose (pretty high)

Not really. High for HRT, yes, High for what most bbers use to gain LBM,
no, it's quite low.

> you'll probably get something but if one
> continued on for more than 10 weeks, other issues would probably
> arise.

Possible, but it still shows how amazingly safe these compounds are and
(yet again) debunks the anti steroid myths.

> So I think the study supports the idea that steroids alone could make
> some changes--and if a person wants to try it, they can do whatever
> they want.

But not recommended!

> But then some people think Bush is smart and Scientology is a
> religion!

No comment!

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GMCarter - 25 Jul 2006 23:25 GMT
>> snip
>> >> Then your friend is misinformed. Anabolic steroids ONLY work in
[quoted text clipped - 15 lines]
>Not really. High for HRT, yes, High for what most bbers use to gain LBM,
>no, it's quite low.

If that's the case, bodybuilders may be doing themselves considerable
harm. But they undoubtedly know that. What is worrisome is if the
"roid rage" is taken out on others.

>> you'll probably get something but if one
>> continued on for more than 10 weeks, other issues would probably
>> arise.
>
>Possible, but it still shows how amazingly safe these compounds are and
>(yet again) debunks the anti steroid myths.

For HRT, I think anabolics are very safe (or can be). Especially gels
or injectable forms that bypass the liver.

>> So I think the study supports the idea that steroids alone could make
>> some changes--and if a person wants to try it, they can do whatever
>> they want.
>
>But not recommended!

I wouldn't recommend somebody use anabolics without exercise. Indeed,
I'd say just do the exercise.

Unless you want one of those bodies which I find rather distorted and
bizarre looking. Whatever floats the proverbial boat, I guess!


>> But then some people think Bush is smart and Scientology is a
>> religion!
>
>No comment!

LOL.

        George M. Carter
Will Brink - 26 Jul 2006 14:19 GMT
> >> snip
> >> >> Then your friend is misinformed. Anabolic steroids ONLY work in
[quoted text clipped - 18 lines]
> If that's the case, bodybuilders may be doing themselves considerable
> harm.

And what do you base that on? The key word there being "may." Millions
of athletes have used high dose AAS over decades and we have at best, a
handful of deaths we can point to as *possibly* being related to AAS. No
doubt, AAS has to follow the three Ds of toxicity, which is drug, dose,
and duration. Regardless, far more people are harmed by drugs many
consider safe then have ever been harmed by AAS. Finally, like
everything, it's a risk to benefit on their part.

>But they undoubtedly know that. What is worrisome is if the
> "roid rage" is taken out on others.

AAS do not turn mr nice guy into an ax murderer. Take a real jerk and
load him up with androgens, yes, it will make him more aggressive, but
booze is far worse in that respect.

> >> you'll probably get something but if one
> >> continued on for more than 10 weeks, other issues would probably
[quoted text clipped - 5 lines]
> For HRT, I think anabolics are very safe (or can be). Especially gels
> or injectable forms that bypass the liver.

Liver issues are overrated but do exist. Liver issues are only a concern
with oral steroids,specifically 17AA oral steroids.

> >> So I think the study supports the idea that steroids alone could make
> >> some changes--and if a person wants to try it, they can do whatever
[quoted text clipped - 7 lines]
> Unless you want one of those bodies which I find rather distorted and
> bizarre looking. Whatever floats the proverbial boat, I guess!

Agreed!

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Will Brink @ www.BrinkZone.com

JMW - 26 Jul 2006 15:12 GMT
> > >> snip
> > >> >> Then your friend is misinformed. Anabolic steroids ONLY work in
[quoted text clipped - 33 lines]
> load him up with androgens, yes, it will make him more aggressive, but
> booze is far worse in that respect.

Amen.  A fact which is re-established daily.
Will Brink - 26 Jul 2006 17:00 GMT
> >  AAS do not turn mr nice guy into an ax murderer. Take a real jerk and
> > load him up with androgens, yes, it will make him more aggressive, but
> > booze is far worse in that respect.
>
> Amen.  A fact which is re-established daily.

Ask any cop how many people he has taken to jail for "roid rage"
compared to "booz rage"

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Will Brink @ www.BrinkZone.com

David  Cohen - 26 Jul 2006 17:04 GMT
> "JMW" <jmwilliams_56@yahoo.com> wrote:
>
[quoted text clipped - 6 lines]
> Ask any cop how many people he has taken to jail for "roid rage"
> compared to "booz rage"

Well, we do have Craig Titus and his woman in our local lockup.

I think it may have been the heat, though, and not the steroids.

David
Will Brink - 26 Jul 2006 20:47 GMT
> > "JMW" <jmwilliams_56@yahoo.com> wrote:
> >
[quoted text clipped - 8 lines]
>
> Well, we do have Craig Titus and his woman in our local lockup.

Is that still making the news out there or are they onto other terrible
stories?

> I think it may have been the heat, though, and not the steroids.

I believe there, as is often the case, a whole mess of different drugs
involved, including AAS. I have a feeling that meth, coke, and two grams
of T a week or so can make people a little edgy....

> David

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JMW - 26 Jul 2006 21:46 GMT
> > "JMW" <jmwilliams_56@yahoo.com> wrote:
> >
[quoted text clipped - 8 lines]
>
> Well, we do have Craig Titus and his woman in our local lockup.

Maybe Craig and Bertil Fox could be pen pals.  They could even
collaborate on a book.

"Body for Lifers"
Will Brink - 26 Jul 2006 22:53 GMT
> > > "JMW" <jmwilliams_56@yahoo.com> wrote:
> > >
[quoted text clipped - 11 lines]
> Maybe Craig and Bertil Fox could be pen pals.  They could even
> collaborate on a book.

They didn't hang Bertil?

> "Body for Lifers"

Would be a best seller!

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JMW - 27 Jul 2006 00:22 GMT
>> > > "JMW" <jmwilliams_56@yahoo.com> wrote:
>> > >
[quoted text clipped - 13 lines]
>
>They didn't hang Bertil?

It appears they intended to do that upon his conviction.  However, on
appeal of his conviction, he confessed to the murders in exchange for
leniency, and he got a life imprisonment.
Will Brink - 27 Jul 2006 01:06 GMT
> >They didn't hang Bertil?
>
> It appears they intended to do that upon his conviction.  However, on
> appeal of his conviction, he confessed to the murders in exchange for
> leniency, and he got a life imprisonment.

Awwww, another happy ending in the bodybuilding world....

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Curt James - 26 Jul 2006 23:55 GMT
[...]

> > Well, we do have Craig Titus and his woman in our local lockup.
>
> Maybe Craig and Bertil Fox could be pen pals.  They could even
> collaborate on a book.
>
> "Body for Lifers"

(groan)

Bertil was given a bum rap, imo, however Titus needs to buuuuurn! And
Ryan, too. GUILTY, GUILTY, GUILTY!!!

http://titusandryan.com/

Signature

Curt

JMW - 26 Jul 2006 17:56 GMT
>> >  AAS do not turn mr nice guy into an ax murderer. Take a real jerk and
>> > load him up with androgens, yes, it will make him more aggressive, but
[quoted text clipped - 4 lines]
>Ask any cop how many people he has taken to jail for "roid rage"
>compared to "booz rage"

They've come up with a cure for booze rage, though.

It's called a Taser.  On-site electroconvulsive therapy.
GMCarter - 26 Jul 2006 22:06 GMT
snip
>> >Not really. High for HRT, yes, High for what most bbers use to gain LBM,
>> >no, it's quite low.
[quoted text clipped - 5 lines]
>of athletes have used high dose AAS over decades and we have at best, a
>handful of deaths we can point to as *possibly* being related to AAS.

"Harm" doesn't automatically equate with "mortality."

As to the data about the risks, I think there are a lot of people who
are very savvy about stacking, cycling, the androgenic features, liver
toxicities and other issues around the various anabolic steroids that
harm can be minimized.

I think others get desperate to bulk up and do too much for their own
health. Do you deny that "roid rage" exists? That CAN be a serious
issue.

>No
>doubt, AAS has to follow the three Ds of toxicity, which is drug, dose,
>and duration. Regardless, far more people are harmed by drugs many
>consider safe then have ever been harmed by AAS. Finally, like
>everything, it's a risk to benefit on their part.

Agreed.

>>But they undoubtedly know that. What is worrisome is if the
>> "roid rage" is taken out on others.
>
> AAS do not turn mr nice guy into an ax murderer. Take a real jerk and
>load him up with androgens, yes, it will make him more aggressive, but
>booze is far worse in that respect.

Could be. I really haven't reviewed the data but would be happy to see
what data you know exist to support the point.

>> >> you'll probably get something but if one
>> >> continued on for more than 10 weeks, other issues would probably
[quoted text clipped - 8 lines]
>Liver issues are overrated but do exist. Liver issues are only a concern
>with oral steroids,specifically 17AA oral steroids.

Agreed. As to whether they are overrated--that's a judgment call I'm
not entirely sure I agree with.

>> >> So I think the study supports the idea that steroids alone could make
>> >> some changes--and if a person wants to try it, they can do whatever
[quoted text clipped - 9 lines]
>
>Agreed!

I ain't a prude. People WILL do what they wish, of course! I think the
best bet is to help people be as best informed as possible about risks
and benefits. In the realm of HIV disease (which is where I have
learned what little I know), I have certainly seen the clinical
benefits of HRT use of anabolics.

        George M. Carter
Will Brink - 26 Jul 2006 22:52 GMT
> snip
> >> >Not really. High for HRT, yes, High for what most bbers use to gain LBM,
[quoted text clipped - 8 lines]
>
> "Harm" doesn't automatically equate with "mortality."

Not saying it is, but harmful effects can be tracked via blood tests,
etc. and are easy enough to control via additional meds, etc.

> As to the data about the risks, I think there are a lot of people who
> are very savvy about stacking, cycling, the androgenic features, liver
> toxicities and other issues around the various anabolic steroids that
> harm can be minimized.

Knowledge is power. Ignorance kills. Applies to all aspects of life and
all drugs; like the number of liver failures per year due to long term
NSAID use. "But doc, it must be safe, I got it at CVS!"

> I think others get desperate to bulk up and do too much for their own
> health.

I am sure that is the case at times, no doubt

>Do you deny that "roid rage" exists? That CAN be a serious
> issue.

It does not exist in the way it's portrayed by the "don't confuse me
with the facts" media. Already outlined the reality behind it below, so
I wont rehash it.

> > AAS do not turn mr nice guy into an ax murderer. Take a real jerk and
> >load him up with androgens, yes, it will make him more aggressive, but
> >booze is far worse in that respect.
>
> Could be. I really haven't reviewed the data but would be happy to see
> what data you know exist to support the point.

I would say the burden of proof is on you in this case to supply *hard*
data to support roid rage. What does exist is not worth the paper it's
printed on to be honest with you.

> >> For HRT, I think anabolics are very safe (or can be). Especially gels
> >> or injectable forms that bypass the liver.
[quoted text clipped - 4 lines]
> Agreed. As to whether they are overrated--that's a judgment call I'm
> not entirely sure I agree with.

That's up to you, but it's a fact. I have read more blood tests in that
area then 10 MDs combined. Studies are quite clear on that. Sick people,
given high doses of liver toxic 17AA steroids (in particular Anadrol)
for long periods of time (years in most cases) finds clear toxicity. In
healthy athletes, increased liver values are transient and often less
then a person taking Motrin too often. Athletes who take very high doses
of known to be liver toxic orals will show elevated liver enzymes that
go back to base line afterward.  So, the media's position that steroids
will make your liver fall out is, in point of fact, FAR overrated and
both data and 50 years of real world experience support that. If you are
really interested in this topic, the best review to date is:

Can J Appl Physiol. 1996 Dec;21(6):421-40.
Androgen use by athletes: a reevaluation of the health risks.
Street C, Antonio J, Cudlipp D.

It has been estimated that 1 to 3 million male and female athletes in
the United States have used androgens. Androgen use has been associated
with liver dysfunction, altered blood lipids, infertility,
musculotendinous injury, and psychological abnormalities. Although
androgens have been available to athletes for over 50 years, there is
little evidence to show that their use will cause any long-term
detriment; furthermore, the use of moderate doses of androgens results
in side effects that are largely benign and reversible. It is our
contention that the incidence of serious health problems associated with
the use of androgens by athletes has been overstated.

> I ain't a prude. People WILL do what they wish, of course! I think the
> best bet is to help people be as best informed as possible about risks
> and benefits.

Exactly, but that's not being allowed by the powers that be due to the
failed "war on drugs" and other pseudo moral bullsh*&.

> In the realm of HIV disease (which is where I have
> learned what little I know), I have certainly seen the clinical
> benefits of HRT use of anabolics.

As have I. A study of interest. They did find elevated liver enzymes,
but as we both know, that is not a sign of liver disfunction per se:

HIV Clin Trials. 2003 May-Jun;4(3):150-63.Click here to read  Links
   Oxymetholone for the treatment of HIV-wasting: a double-blind,
randomized, placebo-controlled phase III trial in eugonadal men and
women.

Department of Dermatology, University of Dusseldorf, Dusseldorf,
Germany.

   BACKGROUND: Despite highly active antiretroviral therapy (HAART),
chronic involuntary weight loss still remains a serious problem in the
care of HIV patients due to various alterations in energy metabolism and
endocrine regulation. Previous studies in HIV-positive men undergoing
androgen replacement therapy or treatment with recombinant growth
hormone (rGH) have shown partial restoration of lean body mass (LBM),
but these treatments have largely not been sufficiently studied in
eugonadal individuals. METHOD: A double-blind, randomized,
placebo-controlled trial of 89 HIV-positive eugonadal women and men with
wasting assigned to the anabolic steroid oxymetholone (50 mg bid or tid)
or placebo for 16 weeks was performed. Body weight, bioimpedance
measurements, quality of life parameters, and appetite were analyzed.
RESULTS: Oxymetholone led to a significant weight gain of 3.0 +/- 0.5
and 3.5 +/- 0.7 kg in the tid and bid groups, respectively (p <.05 for
each treatment versus placebo), while individuals in the placebo group
gained an average of 1.0 +/- 0.7 kg. Body cell mass (BCM) increased in
the oxymetholone bid group (3.8 +/- 0.4 kg; p <.0001) and in the
oxymetholone tid group (2.1 +/- 0.6 kg; p <.005). Significant
improvements were noted in appetite and food intake, increased
wellbeing, and reduced weakness by self-examination. The most important
adverse event was liver-associated toxicity. Overall, 43% of patients in
the tid group, 25% of patients in the bid oxymetholone group, and 8% in
the placebo group had a greater than 5 times baseline increase for ALT,
AST, or gamma GT, while other adverse events were not increased over
placebo. CONCLUSION: Oxymetholone can be considered an effective
anabolic steroid in eugonadal male and female patients with
AIDS-associated wasting. The bid (100 mg/day) regimen appeared to be
equally effective to the tid (150 mg/day) regimen in terms of weight
gain, LBM, and BCM and was associated with less liver toxicity.

Additional studies of interest:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed

>         George M. Carter

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Pete - 27 Jul 2006 02:07 GMT
"GMCarter" <fiar@verizon.net> schreef:

>>Liver issues are overrated but do exist. Liver issues are only a concern
>>with oral steroids,specifically 17AA oral steroids.

> Agreed. As to whether they are overrated--that's a judgment call I'm
> not entirely sure I agree with.

It takes years of using orals to f.ck up the liver completely.

With injectables like testosterone or nandrolone its close to impossible.

I have been using 22 years now, and my liver is in perfect condition, and so
are all the other organs.

(except for my brain...)

----
Pete
noname - 25 Jul 2006 01:50 GMT
> > >Thanks Ron,
> > >
[quoted text clipped - 50 lines]
> when combined with strength training, increase fat-free mass and muscle
> size and strength in normal men.

Does that explain why competitive women bodybuilders are rarely bigger
than men who don't even exercise?
Will Brink - 25 Jul 2006 14:20 GMT
> Does that explain why competitive women bodybuilders are rarely bigger
> than men who don't even exercise?

Nope, and it's not true anyway.

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Pez D Spencer - 21 Jul 2006 02:17 GMT
> Has anyone here used steroids?  What are the side effects?
>
[quoted text clipped - 4 lines]
>
> Should I give them a go?

no, you shouldn't...unless you're a competitive bodybuilder that's
already won some shows.

since you're not putting any information out there, i'll just assume
this is one of those nonsense posts intended to start a flame war.
 
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