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Medical Forum / General / Nutrition / February 2006

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Liebig's Law of the Minimum

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TC - 22 Feb 2006 16:45 GMT
http://en.wikipedia.org/wiki/Liebig%27s_Law_of_the_Minimum

Liebig's Law of the Minimum, often simply called Liebig's Law or the
Law of the Minimum, is a principle developed in agricultural science by
Justus von Liebig. It states that growth is controlled not by the total
of resources available, but by the scarcest resource. This concept was
originally applied to plant or crop growth, where it was found that
increasing the amount of plentiful nutrients did not increase plant
growth. Only by increasing the amount of the limiting nutrient (the one
most scarce in relation to "need") was the growth of a plant or crop
improved.

Liebig used the image of a barrel-now called Liebig's barrel-to
explain his law. Just as the capacity of a barrel with staves of
unequal length is limited by the shortest stave, so a plant's growth is
limited by the nutrient in shortest supply.

Liebig's Law has been extended to biological populations. For example,
the growth of a biological population may not be limited by the total
amount of resources available throughout the year, but by the minimum
amount of resources available to that population at the time of year of
greatest scarcity. That is, the growth of a population of animals might
depend not on how much food is available in summer, but on how much
food is available in winter.

***************

I can see how this would be applicable to humans nutrition and
available nutrients. One scarce nutrient can limit your entire health
potential.

This brings to mind how vegetarianism may have serious and lasting
impact on the health of children and adults.

Or how restricting healthy fats can cause serious problems.

I wonder why this is not used, discussed and referenced more often in
modern medicine.

TC
MMu - 23 Feb 2006 08:46 GMT
> http://en.wikipedia.org/wiki/Liebig%27s_Law_of_the_Minimum
>
> Liebig's Law of the Minimum, often simply called Liebig's Law or the
> Law of the Minimum, is a principle developed in agricultural science by
> Justus von Liebig. It states that growth is controlled not by the total
> of resources available, but by the scarcest resource.

> I wonder why this is not used, discussed and referenced more often in
> modern medicine.

It isn't referenced because, unlike most plants, humans don't grow for their
lifetime.
So quoting that something "hampers growth" would be a lot less meaningful
and could only apply to a certain time of human life.
It is used (in the basic meaning of it), however: although not referenced as
"Liebig's Law".. because that would be about as redundant as referencing
"Newtons Law of Gravity" when talking about trees loosing their leaves in
autumn.
TC - 23 Feb 2006 14:57 GMT
> > http://en.wikipedia.org/wiki/Liebig%27s_Law_of_the_Minimum
> >
[quoted text clipped - 14 lines]
> "Newtons Law of Gravity" when talking about trees loosing their leaves in
> autumn.

I wasn't suggesting that "Liebig's Law" be specifically referenced.
Just the concept of the importance of having all useful nutrients in at
least the minimum amounts needed for optimal and proper development and
health.

But some in the medical maintream seems to not see any importance in
this. In many instances medical people will be anti-vitamin. And some
even actively support an inherently nutrient-deficient diet like
vegetarianism and/or veganism.

And with regards to the "hampers growth" limitation, it makes sense
that this would be obviously applicable only during the active growth
stage. But during that stage of life when growth is not apparent, it
would also be applicable to health in general. Without the minimally
optimal amounts of all useful nutrients, health and/or growth will be
hampered.

TC
MMu - 24 Feb 2006 08:53 GMT
>> > http://en.wikipedia.org/wiki/Liebig%27s_Law_of_the_Minimum
>> >
> I wasn't suggesting that "Liebig's Law" be specifically referenced.
> Just the concept of the importance of having all useful nutrients in at
> least the minimum amounts needed for optimal and proper development and
> health.

But that is the basic meaning of the DRI's (or whatever the recommended
daily intake of essential food components is termed in the different
countries).

They are based on the minimal amounts needed for maintaining health and add
some percentage to that (usually) to come to a recommended intake.

> But some in the medical maintream seems to not see any importance in
> this. In many instances medical people will be anti-vitamin. And some
> even actively support an inherently nutrient-deficient diet like
> vegetarianism and/or veganism.

I think that depends what you call the medical mainstream.
If you are talking about the consensus of the scientific community, then I
disagree-
if you talk about media presence things are a little different.

The scientific idea behind what you probably call being "anti-vitamin" is:
teach people to buy, prepare and eat a healthy diet instead of encouraging
them to just take some vitamin pills because there is more to healthy
nutrition than just having enough vitamins in your diet..

I dont agree that veganism is being pushed either (and I have not yet found
any instance where it was).
Vegetarism is different however.. while you may assume that a
nutrition-uninterested person (for the lack of a better word) on a
vegetarian diet will eventually develop deficiencies most of the vegetarians
are interested in nutrition and have a higher basic knowledge about food and
its contents [which is only natural because being vegetarian in most western
countries is an active choice, not a default option].
That is probably why, in comparisons with non-vegetarians, they do not come
off any worse and sometimes even better than non-vegetarians.

> And with regards to the "hampers growth" limitation, it makes sense
> that this would be obviously applicable only during the active growth
[quoted text clipped - 4 lines]
>
> TC
TC - 24 Feb 2006 14:53 GMT
> >> > http://en.wikipedia.org/wiki/Liebig%27s_Law_of_the_Minimum
> >> >
[quoted text clipped - 6 lines]
> daily intake of essential food components is termed in the different
> countries).

Actually thay are based on the minimum required to avoid overt signs of
disease or deficiency. That is not the same as enduring that one gets
enough for optimal health.

The DRI's are patheticly low, which happens to help the food industry
by holding them to a low nutritional standard and also good for the
medical and the pharma industries by not actually helping people
achieve optimum health.

> They are based on the minimal amounts needed for maintaining health and add
> some percentage to that (usually) to come to a recommended intake.
[quoted text clipped - 8 lines]
> disagree-
> if you talk about media presence things are a little different.

Consumer and popular media is owned by the advertizers who buy the ads,
which are the food and pharma industries for the most part. They also
own the universities that research drugs and health matters and train
the doctors that kick out the prescriptions and determine treatments.

> The scientific idea behind what you probably call being "anti-vitamin" is:
> teach people to buy, prepare and eat a healthy diet instead of encouraging
> them to just take some vitamin pills because there is more to healthy
> nutrition than just having enough vitamins in your diet..

Since when has mainstream medical doctors ever taught people proper
diet. They teach the line which is low fat and high carbs, now it is
whole grain carbs. Whatever the food industry, the USDA, and the pharma
industry wants to push at any given time. The AMA follows the lead that
makes their members the most money and it ain't good nutrition.

The very foundation of good health is good nutrition. And in light of
the poor condition of even our best and freshest foods being produced
by mass production methods, vitamin supplementation is often a damned
good idea.

Without the best foods possible there will not be the best nutrition
and without the best nutrition there will never be the best health.
Vitamin supplementation , in many cases, has become a necessity due to
the poor quality of even our best foods.

> I dont agree that veganism is being pushed either (and I have not yet found
> any instance where it was).
[quoted text clipped - 6 lines]
> That is probably why, in comparisons with non-vegetarians, they do not come
> off any worse and sometimes even better than non-vegetarians.

Actually, many of the better designed and unbiased studies on
vegetarianism shows a marked inferiority in a vegetarian diet. It has
been shown that vegetarian Hindus have up to 3 times the rates of CVDs
as non-vegetarians livng in the same areas. Other studies show that
most vegetarians are deficient of several nutrients. B12, some
essential lipids and some essential proteins.

> > And with regards to the "hampers growth" limitation, it makes sense
> > that this would be obviously applicable only during the active growth
[quoted text clipped - 4 lines]
> >
> > TC

Without excellent nutrition, excellent health is un-attainable. It is
an absolutely essential pre-requisite.

And no pharmaceutical will ever change that.

TC
MMu - 27 Feb 2006 09:37 GMT
> Actually thay are based on the minimum required to avoid overt signs of
> disease or deficiency. That is not the same as enduring that one gets
> enough for optimal health.

But they key word is: "based"- not "equal to". What else could you base
something like this on, other than a measurable adverse effect? (DRI's are
not set to exactly the level where you don't have deficiencies any more,
they are higher than this treshhold- at least in all countries that I know
the specifications of in this area)

> The DRI's are patheticly low, which happens to help the food industry
> by holding them to a low nutritional standard and also good for the
> medical and the pharma industries by not actually helping people
> achieve optimum health.

This is paranoia- there is not a big conspiracy behind everything.
Nobody keeps people from eating healthy, and raising the DRI 30+ percent
won't make people eat healthy either.
Its a decision everyone has to make for himself OR something that the
gouvernment has to dictate by influencing or forcing the economy in a
certain direction (which won't happen).

And: who produces vitamin supplements? Who profits from that?
The calculation just does not solve that way.

> They also
> own the universities that research drugs and health matters and train
> the doctors that kick out the prescriptions and determine treatments.

I doubt that, or rather, I doubt the first part of that. Most universities
in most countries are independent institutions and do not depend on external
resources from the economy directly. Sure, there are crosspoints where
certain projects are sponsored by the economy- but thats why there is a
"Competing Interests Statement" in every good journal that requires
scientists to disclose who sponsored the study.

About the doctors: yes, pharma companies do have a very big influence on
what doctors prescribe-
and no, I don't think that this is a good thing. But it has nothing to do
with DRI's in any way.. just with a specific product being prefered over a
another (maybe more potent) product because the favoured company does not
produce this product.

>> The scientific idea behind what you probably call being "anti-vitamin"
>> is:
[quoted text clipped - 5 lines]
> Since when has mainstream medical doctors ever taught people proper
> diet.

They don't. But that is not their area- or at least not what they learned to
be their area.
If people go to the doctor (especially in the usa) they are already ill in
most cases (which is probably, because there is no general health insurance
like in other countries).

Prevention and public health has become more of a gouvernment issue than one
of your local doctor.

> They teach the line which is low fat and high carbs, now it is
> whole grain carbs. Whatever the food industry, the USDA, and the pharma
> industry wants to push at any given time. The AMA follows the lead that
> makes their members the most money and it ain't good nutrition.

Well, this may be a country specific problem. But there isn't just the US
out there.

About to low-carb or not to low-carb: I am not going to comment on that; it
has become an almost religious question where either party got so blinded by
their crusade against the other that they are not able to make any consense.

> The very foundation of good health is good nutrition. And in light of
> the poor condition of even our best and freshest foods being produced
> by mass production methods, vitamin supplementation is often a damned
> good idea.

Even if by " our " you mean " the USs' ": I doubt that.

While mass production can lower food quality (and most probably does in most
cases to some degree): you are not forced to eat something that is mass
produced- you can buy the more expensive non-mass produced products (and
help the small producers thereby).

But this is how far the will to change goes for most people.. you can always
complain about the bad mass production, but when it comes to taking
consequences (and using your power as a consumer in a land driven by
economy) most just go back to the cheap junk, grinding their teeth in the
process.

> Without the best foods possible there will not be the best nutrition
> and without the best nutrition there will never be the best health.

Well, I agree to the spirit of that- good nutition is the basis for a
healthy life.

> Vitamin supplementation , in many cases, has become a necessity due to
> the poor quality of even our best foods.

I do not agree to that.
You can search the various food data bases: its not a problem to meet your
requirement for all food components by eating food instead of supplements.

> Actually, many of the better designed and unbiased studies on
> vegetarianism shows a marked inferiority in a vegetarian diet.

Well, who decides on a rational, scientific, basis what is biased an what
isn't?
If such a decision would be possible the stury just wouldn't be published in
the first place.
And if it isn't possible: how can it be an argument against a study?

But if you have such studies at hand, please post.

> It has
> been shown that vegetarian Hindus have up to 3 times the rates of CVDs
> as non-vegetarians livng in the same areas. Other studies show that
> most vegetarians are deficient of several nutrients. B12, some
> essential lipids and some essential proteins.

This supports what I said earlier: when vegetarianism is a default you will
probably come off worse than if non-vegetarian but you are talking about a
country (india) with severe malnutrition problems here- this can't be
compared to anything like a western industrialized country where everyone
can buy as much food as he needs (and money is not the limiting factor in
this).

Families in india literally starve- vegetarian or not; this is not the case
in a western county.
Alf Christophersen - 25 Feb 2006 03:18 GMT
>I wasn't suggesting that "Liebig's Law" be specifically referenced.
>Just the concept of the importance of having all useful nutrients in at
>least the minimum amounts needed for optimal and proper development and
>health.

Yes, it is important,

In babies and adolescents still growing that is.

Later, other things are more important as the limiting principle. Like
decreased efficiency in food uptake in intestines, something that
decrease down to almost zero, at which time you dies, anyway. the
longer you manage to keep intestine nutrition uptake in vitality, the
longer you will live.

One way to decrease it is eating too little food, especially proteins,
since a key nutrient is glutamate/glutamine which is the sole energy
fuel in those cells. (Sugar should only be transferred through the
cell):

The glutamate comes partly from diet, but, when starving, the sole
source is muscle cells in full activity. so, combined eating little
food with low protein quality combined with low physical activity is a
sure killer.

After a period of starvation, you will need lot of physical activity
and increased protein quality to recover the damage done to intestinal
cells. But, the increased protein is not for increasing muscle weight,
but to repair damage done to intestinal cells.
MMu - 27 Feb 2006 09:42 GMT
>>I wasn't suggesting that "Liebig's Law" be specifically referenced.
>>Just the concept of the importance of having all useful nutrients in at
[quoted text clipped - 25 lines]
> cells. But, the increased protein is not for increasing muscle weight,
> but to repair damage done to intestinal cells.

True, but how many people have protein-energy-malnutrition in western
countries (kwashiorkor/marasmus/marasmic-kwashiorkor)? People in first world
nations do never get too few protein.
Alf Christophersen - 27 Feb 2006 19:14 GMT
>True, but how many people have protein-energy-malnutrition in western
>countries (kwashiorkor/marasmus/marasmic-kwashiorkor)? People in first world
>nations do never get too few protein.

When ill and having a CRP value above 50 you most probably has protein
malnutrition due to immune system inducing glucagon release in order
to release glutamate for use by several macrophages (which don't use
sugar). That mean, most people being chronically ill very often don't
get enough protein, in turn meaning the disease/infection turns from
acute infection to chronic infection, like in tuberculosis which could
be far better prevented all the long term degradation of body if diet
had supplied enough GSH and taurine (through cystein/methionine intake
or taurine intake directly)

I myself had obvious sign of marasmus during my life-threatening
disease in 2003. Fortunately I did know about importance of protein
and had a whole division of the hospital alone for myself due to
easter celebration, so I had all egg supplies for my own. At the worst
I had around 12 eggs daily. One day they didn't have time for boiling
so many, may foot and leg increased terribly in dimension, so after
some few hours in pain, they thought to give me more eggs and my leg
and feet responded within a few hours. (It was very few things I was
able to eat, most soups because they had removed all teeth except
three in my lower jaw due to infections. In upper jaw they still was
intact because they were too infected with results that no pain
killers would have helped me, and more possible, rather killed me.
MMu - 28 Feb 2006 08:52 GMT
[...]

> I myself had obvious sign of marasmus during my life-threatening
> disease in 2003. Fortunately I did know about importance of protein
[quoted text clipped - 4 lines]
> some few hours in pain, they thought to give me more eggs and my leg
> and feet responded within a few hours.

[...]

You are talking about highly pathologic conditions- people with
life-threatening diseases are not representative for the general population
and its needs when it comes to protein consumption - you probably wouldn't
say that every man and woman in your country should be given antibiotics to
their diet because they helped someone who had a bad infection survive. I
definitely would not recommend anyone to eat 12 whole eggs a day under
normal conditions.
Alf Christophersen - 28 Feb 2006 12:55 GMT
>You are talking about highly pathologic conditions- people with
>life-threatening diseases are not representative for the general population
[quoted text clipped - 3 lines]
>definitely would not recommend anyone to eat 12 whole eggs a day under
>normal conditions.

CRP >50 is normal for a throat Streptococal infection. So no, I'm not
talking about life-threatening conditions, but people with any kind of
infections. As soon as immune system is triggered and macrophages and
other lymphocytes and any other kind of white blood cells are
mobilized, body need more energy, in the form of both glutamate and
glucose and thus trigger both glucagon and adrenaline to increase rate
of release.
 
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