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Medical Forum / General / Nutrition / January 2004

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Why low-carb.

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Ben A. Green - 22 Dec 2003 01:43 GMT
This subject is getting a lot of posts, but I haven't seen a concise review
of the theoretical basis for low-carb dieting for weight loss.  I'm just an
observer of this discussion, but I like the following formulation, (slightly
oversimplified for brevity and clarity):

Macronutrients:

carbohydrates
fat
protein

when digested put the following into the blood:

carbs - glucose
fat     - fatty acids
protein - amino acids

resulting in

carbs - available energy BUT damage to kidneys, eyes, capillaries when
glucose concentration is too high
fat - available energy plus useful material (essential fats)
protein - available energy plus useful material (essential amino acids)

(There are no essential carbs.)

High glucose is a problem that the body solves with insulin.
Insulin scavenges the excess glucose out of the blood.
What happens to the excess glucose? It gets stored in fat cells as fat.

Moral: Keep blood glucose below the level that elicits large amounts of
insulin.
How? Avoid excess carbs, especially carbs that digest quickly.
Or use up the glucose by intense, prolonged exercise.

If this is wrong, tell me about it.

Ben Green
Doug Freese - 22 Dec 2003 11:05 GMT
> when digested put the following into the blood:
>
[quoted text clipped - 6 lines]
> carbs - available energy BUT damage to kidneys, eyes, capillaries when
> glucose concentration is too high

You absolutely must offer a cite for this beauty. Do all the vegans
know this?  I think we better alert them especially those that wear
glasses.

> fat - available energy plus useful material (essential fats)

I notice for carbs you talk about excess, well what about excessive
fat.

> protein - available energy plus useful material (essential amino acids)

And again what about excessive proteins?

Hell, what about excessive calories in general regardless type. If
One's body needs 2000 Kcal a day and I import 2500 a day, regardless
of whence they come, call Goodyear to size up their next blimp.

> How? Avoid excess carbs, especially carbs that digest quickly.
> Or use up the glucose by intense, prolonged exercise.

YOu can also try exercise and not necessarily prolonged (45-60)
minutes days and then eat a delicious balanced diet(less the simple
carbs and bad fat)

> If this is wrong, tell me about it.

Judging from the biasses/myths of your question are you really
looking for valid info?

Signature

Doug Freese
"Caveat Lector"
dfreeseS@NOBShvc.rr.com

Ben A. Green - 22 Dec 2003 13:29 GMT
............

> > fat - available energy plus useful material (essential fats)
>
> I notice for carbs you talk about excess, well what about excessive
> fat.

According to my understanding of the body-builders' diets, a high-fat diet
in the absence of carbs does not lead to fat storage.

> > protein - available energy plus useful material (essential amino acids)
>
> And again what about excessive proteins?

It takes a huge amount of protein to damage the kidneys.

....
> > If this is wrong, tell me about it.
>
> Judging from the biasses/myths of your question are you really
> looking for valid info?

Yes. Thanks for your comments.

Ben
Deirdre Saoirse Moen - 26 Dec 2003 22:38 GMT
> > carbs - available energy BUT damage to kidneys, eyes, capillaries when
> > glucose concentration is too high
>
> You absolutely must offer a cite for this beauty. Do all the vegans
> know this?  I think we better alert them especially those that wear
> glasses.

I think he meant when the person was diabetic -- diabetic retinopathy
isn't so much a direct relationship to sugar, but rather to circulatory
damage from sugar.

During times of darkness, the oxygen requirement of the eyes increases
(rather than decreases) and, in diabetics, they can't get the oxygen to
the eyes. The consequence is hemorrhaging.

http://www.newscientist.com/news/news.jsp?id=ns99992472

Signature

_Deirdre                                         http://deirdre.net
"Dogs may have kept us company on the hunt, but it was the cats who
insisted we invent houses and discover fire."         -- Khiem Tran

ShorThing7 - 22 Dec 2003 11:06 GMT
>If this is wrong, tell me about it.

ok

>carbs - available energy BUT damage to kidneys, eyes, capillaries when
>glucose concentration is too high

Only happens in diabetes so way too paranoid and simplistic

>(There are no essential carbs.)

The brain can only thrive on blood glucose thus CHO eventually becomes an
essential nutrient.  The state of ketosis (arising from CHO deficiency) is not
too healthy either

>High glucose is a problem that the body solves with insulin.
>Insulin scavenges the excess glucose out of the blood.
>What happens to the excess glucose? It gets stored in fat cells as fat.

Insulin helps drive Glu into cells for mitochondrial function and energy
(calorie) utilization. Saying it goes to fat cells for storage in totality is
totally erroneous.

Every body is different and some do better on lower or moderate CHO because
they are prone (likely genetically) to syndrome x / insulin insensitivity /
metabolic syndrome / pre diabetes. These individuals should exercise daily,
moderate CHO with protein at each feeding, supplement with insulin sensitizers,
medication if needed. The propaganda that every human being is better off on
"low carb" diet is a farce and spun to make money.  Seems many are buying it.

Chuck Balzer, MS RD
Ben A. Green - 22 Dec 2003 13:29 GMT
> >If this is wrong, tell me about it.
>
[quoted text clipped - 4 lines]
>
> Only happens in diabetes so way too paranoid and simplistic

Yes, because in diabetes, one's insulin production (if any) is insufficient.
In normals, insulin is what keeps the BG from getting too high.  We have no
disagreement.

> >(There are no essential carbs.)
>
> The brain can only thrive on blood glucose thus CHO eventually becomes an
> essential nutrient.  The state of ketosis (arising from CHO deficiency) is not
> too healthy either

I believe this is wrong. The brain can also thrive on ketones. What is "not
too healthy" is not ketones but ketoacidosis. Two arctic explorers in the
1920's lived for a year on an eskimo diet of protein and fat only under
medical supervision for a year and suffered no ill effects (cited in
Atkins's book).

> >High glucose is a problem that the body solves with insulin.
> >Insulin scavenges the excess glucose out of the blood.
[quoted text clipped - 3 lines]
> (calorie) utilization. Saying it goes to fat cells for storage in totality is
> totally erroneous.

Thank you.

> Every body is different and some do better on lower or moderate CHO because
> they are prone (likely genetically) to syndrome x / insulin insensitivity /
> metabolic syndrome / pre diabetes.

Yes, but what causes people to become insulin-insensitive?  What happened to
millions of Americans in the 1990's to change their cells to
insulin-insensitive? Could it be excessive donuts, soda and french fires?

These individuals should exercise daily,
> moderate CHO with protein at each feeding, supplement with insulin sensitizers,
> medication if needed. The propaganda that every human being is better off on
> "low carb" diet is a farce and spun to make money.  Seems many are buying it.

You may be right. Time will tell. Thanks for your comments.

> Chuck Balzer, MS RD
ShorThing7 - 22 Dec 2003 14:07 GMT
>Yes, because in diabetes, one's insulin production (if any) is insufficient.

Wrong. In fact most diabetics (type2) produce plenty of insulin but the cell
receptivity is altered (obesity or other malfunctions)  

>In normals, insulin is what keeps the BG from getting too high

"Normals" have both adequate insulin and properly functioning insulin reception
at the cellular level.

>I believe this is wrong. The brain can also thrive on ketones

Without glucose the brain will eventually die.

>suffered no ill effects (cited in
>Atkins's book).

Now there is a scientific source without bias

>Yes, but what causes people to become insulin-insensitive?

Theories abound but the strongest are obesity, genetic predisposition, reduced
activity, increased refined CHO.  I have my own additions to that such as heavy
metal toxicity both minute and severe thus altering hormonal and endocrine
balances as well as stresses of our modern world.  Likely a combination of all
of the aforementioned.

> Could it be excessive donuts, soda and french fires?

Certainly exacerbates the obesity part of the equation or actually the
"overfat" part which interferes with insulin function.

>You may be right. Time will tell. Thanks for your comments.

Your welcome.  Good discussion.

Chuck
Ben A. Green - 22 Dec 2003 15:50 GMT
> >Yes, because in diabetes, one's insulin production (if any) is insufficient.
>
> Wrong. In fact most diabetics (type2) produce plenty of insulin but the cell
> receptivity is altered (obesity or other malfunctions)

And BECAUSE the cell receptivity is altered, even "plenty" of insulin is
insufficient.

...
> >I believe this is wrong. The brain can also thrive on ketones
>
[quoted text clipped - 4 lines]
>
> Now there is a scientific source without bias

This can be settled by following up Atkins's references.

> >Yes, but what causes people to become insulin-insensitive?
>
[quoted text clipped - 14 lines]
>
> Chuck
Ben A. Green - 22 Dec 2003 15:57 GMT
> > >Yes, because in diabetes, one's insulin production (if any) is
> insufficient.
> >
> > Wrong. In fact most diabetics (type2) produce plenty of insulin but the
> cell
> > receptivity is altered (obesity or other malfunctions)

And I replied

> And BECAUSE the cell receptivity is altered, even "plenty" of insulin is
> insufficient.

My further comment:

The experience of diabetics gives a clue to the role of insulin in obesity.

Type 2 diabetics produce abundant (although insufficient) insulin. They
typically are very overweight.

Type 1 diabetics produce little or no insulin. They are typically wasting
away no matter how much they eat.

Ben
ShorThing7 - 22 Dec 2003 19:54 GMT
>And BECAUSE the cell receptivity is altered, even "plenty" of insulin is
>insufficient.

Good point.  Some type 2's actually have an over abundance of insulin as the
body tries to adjust through natural homeostasis.  "It falls on deaf cells" if
you will - as you stated - the receptivity is faltered.

>This can be settled by following up Atkins's references.

Just a cheap jab on my part. I think Atkins was a pioneer but I also think he
mixed his venturistic findings with junk science for $$

Chuck
Alf Christophersen - 31 Dec 2003 21:08 GMT
>> receptivity is altered (obesity or other malfunctions)
>
>And BECAUSE the cell receptivity is altered, even "plenty" of insulin is
>insufficient.

there are several ways that make a cell insensible toward insuline.
Lack of chromium bound chromomoduline being one, too much glucagon
(tnf-alfa increases glucagon release and increase sensitivity toward
glucagon in liver cells and diminish insuline sensitivity, tnf-alpha
is a cytokin released in disease, infections etc.

It reminds me that also adipocytes may produce tnf-alpha under certain
circumstances.
George W. Cherry - 01 Jan 2004 00:25 GMT
> >> receptivity is altered (obesity or other malfunctions)
> >
[quoted text clipped - 9 lines]
> It reminds me that also adipocytes may produce tnf-alpha under certain
> circumstances.

I hate it when adipocytes do that.
tcomeau - 22 Dec 2003 14:56 GMT
> >If this is wrong, tell me about it.
>
[quoted text clipped - 4 lines]
>
> Only happens in diabetes so way too paranoid and simplistic

Wrong. It happens in everyone. The degree of insulin resistance and or
inability to produce insulin is a result of how much accumulated
damage has been done to the islet tissues or the beta-cell receptors.
Same with kidneys, eye and capillary damage. Glucose damages them, the
damage is gradual until such time as a person is diagnosed as
pre-diabetic or diabetic. You should be fully aware that it is not a
situation as to whether the tissues are damaged or not but is an
issues as to how much (what degree) of damage is done and does it
produce visible or obvousl symptoms.

> >(There are no essential carbs.)
>
> The brain can only thrive on blood glucose thus CHO eventually becomes an
> essential nutrient.  The state of ketosis (arising from CHO deficiency) is not
> too healthy either

Bullshit. The body can produce the necessary carbs with no carb foods
in the diet whatsoever. The state of ketosis is not a dangerous state.
It is a normal state. You are confusing ketosis with ketoacidosis.

> >High glucose is a problem that the body solves with insulin.
> >Insulin scavenges the excess glucose out of the blood.
[quoted text clipped - 3 lines]
> (calorie) utilization. Saying it goes to fat cells for storage in totality is
> totally erroneous.

Bullshit again. Any basic bio-chemistry textbook will tell you in the
first or second chapter that excess carbs are converted to fat. Your
statement is false, misleading, fraudulent and stupid.

> Every body is different and some do better on lower or moderate CHO because
> they are prone (likely genetically) to syndrome x / insulin insensitivity /
> metabolic syndrome / pre diabetes. These individuals should exercise daily,
> moderate CHO with protein at each feeding, supplement with insulin sensitizers,

Bullshit again. Everybody is not different. We are of the same species
and we metabolize and utilize the three mmacro-nutrients in exactly
the same way. If we were not the same, then all of our bio-chemistry
textbooks are completely wrong. Those with syndrome X / insulin
insensitivity / metabolic syndrome / pre diabetes are all the same as
every one else except they have been damaged by a diet with way to
many refined carbs over too long a period.

When you say moderate CHO you are contradicting every thing you've
said so far. The basis of a low-carb diet is to moderate CHO,
specifically the refined and High-GI-load carbs. Sugars, refined
grains and other high-GI-load foods.

And what exactly are insulin sensitizers?

> medication if needed. The propaganda that every human being is better off on
> "low carb" diet is a farce and spun to make money.  Seems many are buying it.
>
> Chuck Balzer, MS RD

The food and pharma industries has done a good job of creating the
impression that carbs are the best thing since sliced bread, even the
heavily refined and/or sugar overloaded carbs. That is the farce that
we are dealing with here, they did it to make money. And you've bought
into it.

Well Chuck, you've shown us just how misinformed a Registered
Dietition can be. You really do not have a clue. Next time you get an
education, try learning with a bit of a critical mind and don't just
blindly accept everything that is being presented to you.

TC
 
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