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Medical Forum / General / Nutrition / August 2005corporate welfare from NIH
http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 NexBio Receives a $6 Million NIH SBIR Grant for the Clinical Development of a Novel Influenza Medicine Monday August 8, 8:30 am ET SAN DIEGO, Aug. 8 /PRNewswire/ -- NexBio, Inc. announced today that the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), has awarded the company a $6 million Phase II SBIR Grant to further test the company's lead drug candidate, Fludase® (DAS181)*, for the prevention and treatment of influenza. NexBio recently completed a pre-IND (Investigational New Drug Application) meeting with the U.S. Food and Drug Administration (FDA) and will submit an IND to FDA and initiate human trials on Fludase® shortly thereafter. Fludase® represents a First-In-Class approach to fight influenza. The drug candidate works by preventing all types and strains of influenza virus from entering the airway epithelial cells, including avian influenza as well as parainfluenza viruses. It aims at providing broad-spectrum protection, improved clinical efficacy, reduced likelihood of drug resistance, and a cost effective medicine for influenza. Fludase® will not require annual updates as with influenza vaccines, and therefore, it can be stockpiled for both annual influenza epidemics and emergency use for future influenza pandemics. "The US government's strong support has been vital to NexBio's research and development programs on influenza," says Fang Fang, M.D., Ph.D., NexBio's Chief Scientific/Medical Officer. "The mounting threat of an imminent influenza pandemic, the unreliable vaccine supplies for recent influenza epidemics, and increasing viral resistance to the limited selection of antiviral drugs have all added urgency to our cause. NexBio will continue to work closely with the NIH, CDC, and the FDA to expedite Fludase® development. We are also actively seeking corporate partnerships from companies that have extensive experience in late stage drug development and commercialization," added Dr. Fang. Influenza is a highly infectious respiratory disease that has plagued the human race since ancient times. It is characterized by recurrent annual epidemics and periodic major worldwide pandemics. Every year, influenza remains the most common cause of medically attended acute respiratory illness. An influenza pandemic with an H5N1 strain is considered imminent, and is one of the biggest challenges facing public health systems worldwide. The shortage of influenza vaccine in recent years, along with the unavailability of a vaccine for the H5N1 influenza virus, and the emergence of strains resistant to current antiviral compounds, have caused increasingly serious concerns regarding this imminent influenza pandemic. While pursuing a fast-track approval process, NexBio also plans to pursue the possibility of the emergency use of Fludase® and stockpiling in preparation for the influenza pandemic. ABOUT NEXBIO NexBio, Inc. is a privately held development-stage biopharmaceutical company located in San Diego. NexBio's mission is to develop novel, broad-spectrum prophylaxis and therapeutics for the prevention and treatment of life-threatening human respiratory infectious diseases in order to save lives and to improve the quality of life. ********** taxpayers footing bill for corporation, is this really needed? TC http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 NexBio Receives a $6 Million NIH SBIR Grant for the Clinical Development of a Novel Influenza Medicine Monday August 8, 8:30 am ET SAN DIEGO, Aug. 8 /PRNewswire/ -- NexBio, Inc. announced today that the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), has awarded the company a $6 million Phase II SBIR Grant to further test the company's lead drug candidate, Fludase® (DAS181)*, for the prevention and treatment of influenza. NexBio recently completed a pre-IND (Investigational New Drug Application) meeting with the U.S. Food and Drug Administration (FDA) and will submit an IND to FDA and initiate human trials on Fludase® shortly thereafter. Fludase® represents a First-In-Class approach to fight influenza. The drug candidate works by preventing all types and strains of influenza virus from entering the airway epithelial cells, including avian influenza as well as parainfluenza viruses. It aims at providing broad-spectrum protection, improved clinical efficacy, reduced likelihood of drug resistance, and a cost effective medicine for influenza. Fludase® will not require annual updates as with influenza vaccines, and therefore, it can be stockpiled for both annual influenza epidemics and emergency use for future influenza pandemics. "The US government's strong support has been vital to NexBio's research and development programs on influenza," says Fang Fang, M.D., Ph.D., NexBio's Chief Scientific/Medical Officer. "The mounting threat of an imminent influenza pandemic, the unreliable vaccine supplies for recent influenza epidemics, and increasing viral resistance to the limited selection of antiviral drugs have all added urgency to our cause. NexBio will continue to work closely with the NIH, CDC, and the FDA to expedite Fludase® development. We are also actively seeking corporate partnerships from companies that have extensive experience in late stage drug development and commercialization," added Dr. Fang. Influenza is a highly infectious respiratory disease that has plagued the human race since ancient times. It is characterized by recurrent annual epidemics and periodic major worldwide pandemics. Every year, influenza remains the most common cause of medically attended acute respiratory illness. An influenza pandemic with an H5N1 strain is considered imminent, and is one of the biggest challenges facing public health systems worldwide. The shortage of influenza vaccine in recent years, along with the unavailability of a vaccine for the H5N1 influenza virus, and the emergence of strains resistant to current antiviral compounds, have caused increasingly serious concerns regarding this imminent influenza pandemic. While pursuing a fast-track approval process, NexBio also plans to pursue the possibility of the emergency use of Fludase® and stockpiling in preparation for the influenza pandemic. ABOUT NEXBIO NexBio, Inc. is a privately held development-stage biopharmaceutical company located in San Diego. NexBio's mission is to develop novel, broad-spectrum prophylaxis and therapeutics for the prevention and treatment of life-threatening human respiratory infectious diseases in order to save lives and to improve the quality of life. ********** taxpayers footing bill for corporation, is this really needed? TC "Crisis" entered the medical lexicon to describe that critical point in a disease when the patient either recovers or succumbs. In this sense, "crisis" aptly describes the state of funding for Canadian research in the health sciences, and the outcome of this crisis is uncertain. Canada lags far behind the other major industrialized G7 nations in its funding for medical research, as summarized below. (A detailed statement can also be found in the recent report A Crisis in Health Research,1 published by the Coalition for Biomedical and Health Research (CBHR) and available on the CBHR Web site at www.cbhr.ca). http://epe.lac-bac.gc.ca/100/201/300/cdn_medical_association/cim/vol-21/issue-3/ 0159.htm > http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 > [quoted text clipped - 72 lines] > > http://epe.lac-bac.gc.ca/100/201/300/cdn_medical_association/cim/vol-21/issue-3/ 0159.htm Just because European countries and the US think it is right to spend billions to do research on behalf of the food and pharceutical industries, to their sole benefit, does not mean it is useful or needed. In Canada, we don't subscribe to the idea of providing corporate welfare to develop medically questionable and most likely dangerous drug treatments. We are more interested in actually providing real health care to our people. The research we do is much more relevant and has led to many more significant and truly scientific findings than all of the billions spent by the US to bolster their food and pharma industry with fake "marketing" science. Canadian science, so far, has been much more focussed and productive than the american "marketing" science, and will continue to be, in spite of the smaller amount spent. Quality in science will always trump quantity, especially the quantity of garbage science the US is producing. Everyone in Canada has access to health care. And our average life span is longer than in the US, as are most developed countries. Why are these billions that are being spent on research in the US not translating into real health benefits in the US? That is the failure of the US system. They spend way more per capita for health care and health related research than anyone else in the entire world, and they not only see no results, but they see massive negative results in health status. They are fatter and sicker the the entire rest of the world. They lead the world in health and research spending and the lead the world in obesity and sickness. And that sh.t is happening because the billions of tax dollars being spent on "research" are being spent on biased garbage "marketing" science instead of real life-saving health science. TC Robert wrote: > http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 > [quoted text clipped - 70 lines] > Coalition for Biomedical and Health Research (CBHR) and available on the > CBHR Web site at www.cbhr.ca). http://epe.lac-bac.gc.ca/100/201/300/cdn_medical_association/cim/vol-21/issue-3/ 0159.htm Just because European countries and the US think it is right to spend billions to do research on behalf of the food and pharceutical industries, to their sole benefit, does not mean it is useful or needed. In Canada, we don't subscribe to the idea of providing corporate welfare to develop medically questionable and most likely dangerous drug treatments. We are more interested in actually providing real health care to our people. The research we do is much more relevant and has led to many more significant and truly scientific findings than all of the billions spent by the US to bolster their food and pharma industry with fake "marketing" science. Canadian science, so far, has been much more focussed and productive than the american "marketing" science, and will continue to be, in spite of the smaller amount spent. Quality in science will always trump quantity, especially the quantity of garbage science the US is producing. Everyone in Canada has access to health care. And our average life span is longer than in the US, as are most developed countries. You are a Canadian propagandist for the Canadian government. You appoligize for every single flaw and crap done by the government. You are simply a troll. > Robert wrote: > > http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 [quoted text clipped - 95 lines] > You appoligize for every single flaw and crap done by the government. > You are simply a troll. Look, moron.... The topic is corruption deep within the bowels of the *US* NIH. If you want to criricize the Canadian system, you are free to do so. Please feel free to start your own threads on the topic of Canadian corruption in the health field. If I feel compelled I will respond. Do you see how absurd your logic is? I post an article that clearly spells out the details of abject corruption in the US health system, you respond by pointing out some malfeasance in the Canadian system. Well... so what? So your massive american funded systemic corporate corruption reaches as far as 50 miles north of the US-Canada border. So what? So Canadian officials and elected officials get pressured to support the conservative Bush agenda and drug policy. So what? I don't care if it is in the US or Canada. It does not matter. The corruption is there. What are you going to do about it? Are you defending the corruption? TC "TC" <tunderbar@hotmail.com> wrote in message > > Look, moron.... The topic is corruption deep within the bowels of the *US* NIH. If you want to criricize the Canadian system, you are free to do so. Please feel free to start your own threads on the topic of Canadian corruption in the health field. If I feel compelled I will respond. Do you see how absurd your logic is? I post an article that clearly spells out the details of abject corruption in the US health system, you respond by pointing out some malfeasance in the Canadian system. Well... so what? SO WHAT. WHAT ARE CANADIANS going to do about it? You as a Canadian looked at press reports about US healthcare. SO WHAT. What are you going to do about it? You post it here. SO WHAT? As a Canadian, what do you want Americans to do about it? SO what if they do or don't do anything about it? So your massive american funded systemic corporate corruption reaches as far as 50 miles north of the US-Canada border. So what? So Canadian officials and elected officials get pressured to support the conservative Bush agenda and drug policy. So what? Now the truth comes out. So post in Canada about the Canadian health system corruption so crippled that it relies totally on the FDA and NIH. Change your own stupid system before as an idiot Canadian trying to change the American system. I don't care if it is in the US or Canada. It does not matter. The corruption is there. What are you going to do about it? Are you defending the corruption? TC You damn well do. Every bad thing up in Canada you have excuses for because you support the government there. The same government you say that follows the FDA. Fix your own mess. > "TC" <tunderbar@hotmail.com> wrote in message > > > Look, moron.... [quoted text clipped - 10 lines] > > SO WHAT. WHAT ARE CANADIANS going to do about it? We are doing it. > You as a Canadian looked at press reports about US healthcare. Yep, so what? > SO WHAT. What are you going to do about it? > You post it here. SO WHAT? > As a Canadian, what do you want Americans to do about it? Just to be aware of it. We are aware of our problems. You guys, for the most part, never see it reported in the main press. > SO what if they do or don't do anything about it? Why are you getting your bun in a knot? > So your massive american funded systemic corporate > corruption reaches as far as 50 miles north of the US-Canada border. So [quoted text clipped - 5 lines] > your own stupid system before as an idiot Canadian trying to change the > American system. We don't rely on the FDA and NIH. We know it is all corrupt crap. We have out own processes up here and it works on a lot less than the billions you guys throw at pharma. Let's see, the US spends billions of taxpayers money to help pharma rip off their own citizens with expensive, dangerous and pretty much useless drugs, Canada doesn't, and Canada is the stupid one. All Canadians have health care and forty percent of US citizens have virtually none and Canada is the stupid system? Canada allows medicare to negotiate drug prices, the US makes it illegal for their medicare to negotiate drug prices and Canada is the stupid one? > I don't care if it is in the US or Canada. It does not matter. The > corruption is there. What are you going to do about it? [quoted text clipped - 5 lines] > You damn well do. Every bad thing up in Canada you have excuses for because > you support the government there. Bullshit. I've yet to make an excuse for any corruption in Canada. It just does not exist to the same or even vaguely similar extent as it does in the NIH and the FDA. And you haven't proven that it does. > The same government you say that follows the FDA. It doesn't follow the FDA. It takes the FDA's information and considers it, just as it does many other countries FDA equivalents around the world, notably in Europe. > Fix your own mess. Our mess is publicly acknowledged and under control, is yours? TC > We don't rely on the FDA and NIH. We know it is all corrupt crap. We > have out own processes up here and it works on a lot less than the > billions you guys throw at pharma. COMMENT: "Works on a lot less"?? LOL! Canadian biomed research doesn't do much work at all, so far as I can see. Whereas in theory, since the incorruptable Canadian system is free of the corrupt FDA and corrupt US Pharm industries, it should be free to pump out new efficacious and safe medications with the incorruptable efficiency of....metaphor search.... Sergeant Preston of the Yukon RCMP. ("On King! On you huskies...") Did I miss something? I don't see all these marvels coming down from Canada these days. The only thing I see coming DOWN is Canadian biotech stock prices. > Let's see, the US spends billions of taxpayers money to help pharma rip > off their own citizens with expensive, dangerous and pretty much > useless drugs, Canada doesn't, and Canada is the stupid one. COMMENT: Canada uses all those same drugs, so I'm told (though I still can't discover if you can get Lamasil pills for your ugly toenails in Canuckistan, and if you can, how much they cost). If these drugs you're talking about are truely as expensive and dangerous as you say, why do you import them at all? Isn't there something homeopathic or locally invented you can use, instead? Flavored moose droppings, or something? >All Canadians have health care and forty percent of US citizens have > virtually none and Canada is the stupid system? COMMENT No, I have to admit that Canada has been pretty smart about hanging back and cloning technologies that first prove themselves elsewhere. That's a good way to save money, all right. Gosh, we're sure stupid for not doing that here in the US. I don't KNOW why we didn't think of it. Thanks for pointing that out. SBH PS. Now, how are we supposed to get Canada's strategy to work down here, again? > > http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 > > [quoted text clipped - 20 lines] > > vaccines, and therefore, it can be stockpiled for both annual influenza > > epidemics and emergency use for future influenza pandemics. COMMENT: Why isn't this thread entitled "US foreign aid to Canada, from NIH?" After all, this money is being used to develop a blockbuster anti-flu drug that Canada is certain to buy and use, no? What, Canada is going to refuse to have anything to do with Fludase, because it was funded by US taxpayers and corporate welfare? I don't think so. > Just because European countries and the US think it is right to spend > billions to do research on behalf of the food and pharceutical > industries, to their sole benefit, does not mean it is useful or > needed. COMMENT: If you didn't think it was "useful or needed," you'd be refusing to avail yourselves of the fruits of it, forever. I don't see that happenning. Canada might wait till the price comes down, but it will buy eventually. >In Canada, we don't subscribe to the idea of providing > corporate welfare to develop medically questionable and most likely > dangerous drug treatments. COMMENT: No, you subscribe to the policy of letting the US Taxpayer do it, after which you buy the surviving drug treatments later, at hand-me-down prices. >We are more interested in actually providing > real health care to our people. COMMENT: You are more interested in freeloading and other people's garage-sales. >The research we do is much more > relevant and has led to many more significant and truly scientific > findings than all of the billions spent by the US to bolster their food > and pharma industry with fake "marketing" science. COMMENT: Examples needed here. Insulin was 75 years ago, and the commercialization of it, as with penicillin, was not trivial, and was a significant peice of scientific work in and of itself, if you know that story. >Canadian science, so > far, has been much more focussed and productive than the american > "marketing" science, and will continue to be, in spite of the smaller > amount spent. Quality in science will always trump quantity, especially > the quantity of garbage science the US is producing. COMMENT: Are you really trolling here? SBH > > > http://biz.yahoo.com/prnews/050808/lam050.html?.v=19 > > > [quoted text clipped - 78 lines] > > SBH You know that you've hit a real nerve with these shameless pharma apologists in this ng when they go nuts about where you are from and are completely unable to come up with anything to say about the content original post. Check and mate. TC |
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