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Medical Forum / General / Nutrition / July 2005

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Weight loss and ketones

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Jimmy - 03 Jul 2005 05:00 GMT
Hi all,

I found this statement on an article about weight loss and I wonder
if anyone could comment on its reliability:

"The first way to know that you are actually about to start burning fat
deposits in your body is hunger.
To feel a little hungry when you first begin a weight loss diet is
good! It
means that your body can't find enough sugars or carbs to keep going.
Hunger is
the signal that your body is about to reach into your "fat
warehouse" to find
nourishment for metabolism.

Every diet or supplement that results in fat loss is ketogenic .
Any time your body burns fat, chemicals called ketones are produced.
Ketones are byproducts of burning fat.
If you are burning significant amounts of fat, these ketones will
be measurable in your urine.
Ketone test strips are an invaluable tool for all serious dieters.
They give you immediate feedback on just how much fat you are
metabolizing
(burning) at any time.

Overweight people just need to eat less, right? Wrong! In fact, studies
show that many overweight people eat no more than thin people.
The problems really start when you try to lose weight by cutting back
on
calories. You skip breakfast. Eat a small salad for lunch and a diet
microwave
dish for dinner.
And here is where testing for ketones becomes even more important.
Because if you are losing weight, but you are not burning fat- you are
losing
muscle tissue."

If all weight-loss diets are ketogenic, why there are specific diets
that are are called ketogenic?
Can ketones strips be really useful to check weight loss?
Is a lack of ketones in the urines while losing weight really a sign
that the body is burning muscles instead of fat?

Thanks

J. David
Mr-Natural-Health - 03 Jul 2005 13:20 GMT
> "The first way to know that you are actually about to start burning fat
> deposits in your body is hunger.

???

Why are fat people so mental?

If you don't eat amy food you will eventually starve to death.  The
logic of that statement should be the only thing anyone needs to manage
their own weight.

The problem with fat people is that they actually think that losing fat
is a destination that that they buy and obtain instantly, with money,
just like they can buy a Big Mac at McDonald's.

Sorry, but that is not how life works. :)
RBR - 05 Jul 2005 04:31 GMT
>> "The first way to know that you are actually about to start burning fat
>> deposits in your body is hunger.
>
>???
>
>Why are fat people so mental?

Why are fat-headed jerks that call themselves "The Man" so mental.

>If you don't eat amy food you will eventually starve to death.  The
>logic of that statement should be the only thing anyone needs to manage
[quoted text clipped - 5 lines]
>
>Sorry, but that is not how life works. :)

Ha, ... Hah, Ha!

Fortunately evolution gave you such a small pecker that you cannot
procreate, not that any woman would actually want you sticking that
pitiful little thing in them. We can all breath a sigh of relief to
know that your kind will end when you do. Isn't evolution wonderful?
:)

Just thought you would want to know.

RBR
Enrico C - 04 Jul 2005 01:45 GMT
On 2 Jul 2005 21:00:46 -0700, Jimmy wrote in
<news:1120363246.100224.153940@g43g2000cwa.googlegroups.com> on
sci.med.nutrition :

> Hi all,
>
[quoted text clipped - 42 lines]
>
> J. David

Did yoy try and search Pubmed for those topics?

http://www.pubmedcentral.nih.gov/
Jeff - 04 Jul 2005 01:51 GMT
> Hi all,
>
[quoted text clipped - 12 lines]
>
> Every diet or supplement that results in fat loss is ketogenic .\\

Not true. It is nomal to burn fat without generating a large number of
ketones. People do it literally all the time.

> Any time your body burns fat, chemicals called ketones are produced.
> Ketones are byproducts of burning fat.
> If you are burning significant amounts of fat, these ketones will
> be measurable in your urine.

I am pretty sure that for ketones to appear, your  body has to be unable to
utilize glucose. In the ketogenic diet used to treat epilespy, very little
sugar is used. Likewise, in diabetics who are ketogenic, they are unable to
utilize much sugar because of their condition.

That means people who are able to utilize sugar normally don't become
ketogenic when they burn fats.

Jeff

> Ketone test strips are an invaluable tool for all serious dieters.
> They give you immediate feedback on just how much fat you are
[quoted text clipped - 22 lines]
>
> J. David
Silver - 04 Jul 2005 13:33 GMT
Jeff ha scritto:
> That means people who are able to utilize sugar normally don't become
> ketogenic when they burn fats.

Athletes have high ketones level in their blood when they finish their
training even though they don't have that high level during the day.
This means healthy persons produce ketones when they burn fat, but these
go away after a while.

P.S. Sorry for my English
Susan - 04 Jul 2005 02:51 GMT
> Hi all,
>
[quoted text clipped - 10 lines]
> warehouse" to find
> nourishment for metabolism.

This hasn't been my experience.  I burn fat and lose weight without
hunger, even with very low calorie ketogenic dieting.

Further, many folks with morbid obesity find the lack of hunger on
ketogenic diets is what allows them to succeed where they've failed on
other diets before.

That's not to say that going hungry won't cause weight loss, too, but
the feeling of hunger is not necessary.

> Every diet or supplement that results in fat loss is ketogenic .
> Any time your body burns fat, chemicals called ketones are produced.
> Ketones are byproducts of burning fat.
> If you are burning significant amounts of fat, these ketones will
> be measurable in your urine.

Not true in many cases.  If you're not overeating fat and/or calories,
you may burn enough ketones for fuel that they don't show up in your urine.

> Ketone test strips are an invaluable tool for all serious dieters.

Completely false.

> They give you immediate feedback on just how much fat you are
> metabolizing
> (burning) at any time.

No, they don't distinguish between fat you've eaten and body stores
you're burning.

> Overweight people just need to eat less, right? Wrong! In fact, studies
> show that many overweight people eat no more than thin people.
[quoted text clipped - 7 lines]
> losing
> muscle tissue."

Testing for ketones tells you nothing about how your diet is working.
Weight loss, feeling good and body recomposition tells you if your diet
is working.  Use a scale and a tape measure to measure *real* results.

> If all weight-loss diets are ketogenic, why there are specific diets
> that are are called ketogenic?

Because ketogenic diets sustain the fat burning requirement.  Eat enough
carbs, and your body will burn glucose instead of fat stores.

> Can ketones strips be really useful to check weight loss?

No, you can gain weight while registering positive on ketone strips if
you eat too much.

> Is a lack of ketones in the urines while losing weight really a sign
> that the body is burning muscles instead of fat?

NO.

Susan
Enrico C - 04 Jul 2005 11:38 GMT
> x-no-archive: yes

[...]

>> If all weight-loss diets are ketogenic, why there are specific diets
>> that are are called ketogenic?
>
> Because ketogenic diets sustain the fat burning requirement.  Eat enough
> carbs, and your body will burn glucose instead of fat stores.
[...]

What if you eat "enough fat" or "enough protein" instead of "enough carbs".

Signature

Enrico C

Susan - 04 Jul 2005 16:49 GMT
>>x-no-archive: yes
>
[quoted text clipped - 9 lines]
>
> What if you eat "enough fat" or "enough protein" instead of "enough carbs".

Protein is converted to glucose at a rate of about 58%.  In the absence
of more readily available glucose, the body can create fuel from fat.

I believe I said earlier that eating too much will lead to weight gain
or failure to lose even if one is registering ketones.

Happened to me years ago; I gained on Atkins' induction level.  It
caused my T3 to drop below normal.

Susan
Enrico C - 05 Jul 2005 09:40 GMT
> x-no-archive: yes
>
[quoted text clipped - 20 lines]
> Happened to me years ago; I gained on Atkins' induction level.  It
> caused my T3 to drop below normal.

Ok, but what about the (supposed? real? I don't know) "metabolic benefit"?

http://www.pubmedcentral.gov/articlerender.fcgi?tool=pmcentrez&artid=538279
(free full text)

Nutr Metab (Lond). 2004; 1: 13.
Published online 2004 November 8. doi: 10.1186/1743-7075-1-13.
Copyright © 2004 Volek et al; licensee BioMed Central Ltd.

Comparison of energy-restricted very low-carbohydrate and low-fat diets on
weight loss and body composition in overweight men and women

JS Volek,1 MJ Sharman,1 AL Gómez,1 DA Judelson,1 MR Rubin,1 G Watson,1 B
Sokmen,1 R Silvestre,1 DN French,1 and WJ Kraemer1
1Human Performance Laboratory, Department of Kinesiology, University of
Connecticut, 2095 Hillside Road, Unit-1110, Storrs, CT 06269-1110, USA

Corresponding author.

JS Volek: jeff.volek@uconn.edu; MJ Sharman: matthew.sharman@uconn.edu; AL
Gómez: candelita16@yahoo.com; DA Judelson: gangus_13@hotmail.com; MR Rubin:
RUBIN_MARTYN_R@Lilly.com; G Watson: greig.watson@huskymail.uconn.edu; B
Sokmen: bulent.sokmen@huskymail.uconn.edu; R Silvestre:
ricsilvestre@hotmail.com; DN French: duncfrench28@hotmail.com; WJ Kraemer:
william.kraemer@uconn.edu

Received July 27, 2004; Accepted November 8, 2004.

This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.
Top
>>> Abstract
Introduction
Methods
Results
Discussion
Supplementary Material
References
   
Abstract

Objective

To compare the effects of isocaloric, energy-restricted very
low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss,
body composition, trunk fat mass, and resting energy expenditure (REE) in
overweight/obese men and women.

Design

Randomized, balanced, two diet period clinical intervention study. Subjects
were prescribed two energy-restricted (-500 kcal/day) diets: a VLCK diet
with a goal to decrease carbohydrate levels below 10% of energy and induce
ketosis and a LF diet with a goal similar to national recommendations
(%carbohydrate:fat:protein = ~60:25:15%).

Subjects

15 healthy, overweight/obese men (mean ± s.e.m.: age 33.2 ± 2.9 y, body
mass 109.1 ± 4.6 kg, body mass index 34.1 ± 1.1 kg/m2) and 13 premenopausal
women (age 34.0 ± 2.4 y, body mass 76.3 ± 3.6 kg, body mass index 29.6 ±
1.1 kg/m2).

Measurements

Weight loss, body composition, trunk fat (by dual-energy X-ray
absorptiometry), and resting energy expenditure (REE) were determined at
baseline and after each diet intervention. Data were analyzed for between
group differences considering the first diet phase only and within group
differences considering the response to both diets within each person.

Results

Actual nutrient intakes from food records during the VLCK
(%carbohydrate:fat:protein = ~9:63:28%) and the LF (~58:22:20%) were
significantly different. Dietary energy was restricted, but was slightly
higher during the VLCK (1855 kcal/day) compared to the LF (1562 kcal/day)
diet for men. Both between and within group comparisons revealed a distinct
advantage of a VLCK over a LF diet for weight loss, total fat loss, and
trunk fat loss for men (despite significantly greater energy intake). The
majority of women also responded more favorably to the VLCK diet,
especially in terms of trunk fat loss. The greater reduction in trunk fat
was not merely due to the greater total fat loss, because the ratio of
trunk fat/total fat was also significantly reduced during the VLCK diet in
men and women. Absolute REE (kcal/day) was decreased with both diets as
expected, but REE expressed relative to body mass (kcal/kg), was better
maintained on the VLCK diet for men only. Individual responses clearly show
the majority of men and women experience greater weight and fat loss on a
VLCK than a LF diet.

Conclusion

This study shows a clear benefit of a VLCK over LF diet for short-term body
weight and fat loss, especially in men. A preferential loss of fat in the
trunk region with a VLCK diet is novel and potentially clinically
significant but requires further validation. These data provide additional
support for the concept of metabolic advantage with diets representing
extremes in macronutrient distribution.

Keywords: weight loss, Atkins diet, hormones, abdominal fat, regional body
composition, low-carbohydrate diet
[...]
Susan - 05 Jul 2005 17:33 GMT
> Ok, but what about the (supposed? real? I don't know) "metabolic benefit"?

Longer studies have found that the weight loss evens out at about 6 mos
to one year between LC and LF.

Susan
 
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