Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / General / Nutrition / July 2005

Tip: Looking for answers? Try searching our database.

ascorbic acid, tyrosinase, scurvey, etc

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
ajnast4r@gmail.com - 24 Jun 2005 00:41 GMT
I remember reading that ascorbic acid alone would not cure scurvey, but
citrus juice would...because the ascorbic acid was just a 'bodyguard'
for tyrosinase & other things and has no real nutritional value. ive
heard people preach the dangers and the wonders of taking ascorbic
acid. ide be thankful if someone could point me to some solid science
backed info, rather than just opitions..

ive also read that a 'right spin' L-ascorbic acid is the type of
ascorbic acid that has value in the human body... would anyone care to
comment on that aand again, point me towards some solid info?

thanks alot
Pizza Girl. - 24 Jun 2005 01:35 GMT
Nature's blends usually know best for the body.

> I remember reading that ascorbic acid alone would not cure scurvey, but
> citrus juice would...because the ascorbic acid was just a 'bodyguard'
[quoted text clipped - 8 lines]
>
> thanks alot
MMu - 24 Jun 2005 13:33 GMT
>I remember reading that ascorbic acid alone would not cure scurvey, but
> citrus juice would...because the ascorbic acid was just a 'bodyguard'
> for tyrosinase & other things and has no real nutritional value. ive
> heard people preach the dangers and the wonders of taking ascorbic
> acid. ide be thankful if someone could point me to some solid science
> backed info, rather than just opitions..

This information is not correct. its most often heard from
supplement-manufacturers who want to sell their berry-extracts. Ascorbic
acid alone is routinely used to cure scurvey for years, there is not a doubt
that it is a vitamin (which is, per definition, something "vital").

Vitamin C has not all to many dangers as long as its taken in somewhat
reasonable ammounts..
diarrhea is associated with overdoses;
forming of renal stones (oxalate stones) is in discussion as well.
Generally vitamin C is not much of a risk when it comes to overdosing due to
good water soluability.

It does not work wonders, however it does have a broad palette of functions
from stabilizing prolylhydroxylases (in connective tissue, in the hypoxia
inducible factor pathway etc), stabilizing tetrahydrobiopterin in the NOS
signaling pathway and acting as an antioxidant and a regenerator for
tocopherol. This does not mean that taking huge ammounts of it will do all
these things better.. most ascorbic acid above a certain level in a megadose
is simply excreted.

its like when people are building a house..
it won't be finished faster just because you supply the tenfold ammount of
working material needed.

> ive also read that a 'right spin' L-ascorbic acid is the type of
> ascorbic acid that has value in the human body... would anyone care to
> comment on that aand again, point me towards some solid info?

Vitamin C is a group of chemical substances with vitamin c activity.
Those are:
Dehydroascorbic acid, L-ascorbic acid, D-ascorbic acid.

L-ascorbic acid is the one we refer to usually when saying "ascorbic acid"
or "vitamin C" in a clinical context, it has the strongest bioactivity.
The enantiomer with very small vitamin C bioactivity is D-ascorbic acid-
maybe thats what they meant.
Dehydroascorbic acid (DHA) is a metabolite of ascorbic acid decomposition
with smaller bioactivity than ascorbic acid and way shorter half-life (gets
oxidized quickly).
(D and L nomenclature is old nomenclature and almost exclusively used for
sugar chemistry- R and S nomenclature should be used generally)

With right spin and left spin they probably meant the optical activity (the
rotation of polarized light caused by interaction with the molecules).

In chemical terminology they are written with (+) or "d" (notice: no caps)
for right spin or clockwise spin and (-) or "l" for left spin or
counterclockwise spin of polarized light passing through the molecules.
L(+)ascorbic acid is "L-ascorbic acid", so the biologically active form of
ascorbic acid spins polarized light clockwise (right). The other form is the
D(-)ascorbic acid and spins light left.

You should find the above information (and more on it) in any textbook on
organic chemistry and in some biochemistry textbooks as well.

> thanks alot
ajnast4r@gmail.com - 24 Jun 2005 22:50 GMT
awsome.. thats exactly what i wanted to hear. thanks man
Pizza Girl. - 25 Jun 2005 03:42 GMT
That is just not true.

Vitamin C doesn't do half the job that the included biflavenoids along with
vitamin C does. They are synergetic and vitamin C alone does a very poorjob
of healing tissues if at all.

> awsome.. thats exactly what i wanted to hear. thanks man
ajnast4r@gmail.com - 25 Jun 2005 05:12 GMT
proof, anyone?
Mr-Natural-Health - 25 Jun 2005 11:46 GMT
> vitamin C alone does a very poorjob
> of healing tissues if at all.

Pure ascorbic acid worked for me!  It cured my gum bleeding problems
(otherwise known as modern borderline scurvy from eating a fast food
diet) practically overnight.

Just thought that you might want to know, fruit.
Sbharris[atsign]ix.netcom.com - 25 Jun 2005 19:25 GMT
>>Pure ascorbic acid worked for me!  It cured my gum bleeding problems
(otherwise known as modern borderline scurvy from eating a fast food
diet) practically overnight. <<

COMMENT:

Must've been back when you had teeth. Inasmuch as toothless people
don't get gum bleeding from scurvy.

SBH
Pizza Girl. - 26 Jun 2005 03:16 GMT
That was just a rumour he spread around about himself to get the price for
his services up.

> >>Pure ascorbic acid worked for me!  It cured my gum bleeding problems
> (otherwise known as modern borderline scurvy from eating a fast food
[quoted text clipped - 6 lines]
>
> SBH
noz - 27 Jun 2005 10:22 GMT
have you visited http://www.vitamincfoundation.org ?
noz - 27 Jun 2005 10:29 GMT
try to find out how much vitamin c is produced daily by animals, this
is the sort of quantity that you will need to improve health.  You will
be surprised at the amount of vitamin c that our organs need to
function properly, especially adrenals, pituitary,brain, eyes, thyroid
and liver.
MMu - 27 Jun 2005 11:26 GMT
> try to find out how much vitamin c is produced daily by animals, this
> is the sort of quantity that you will need to improve health.  You will
> be surprised at the amount of vitamin c that our organs need to
> function properly, especially adrenals, pituitary,brain, eyes, thyroid
> and liver.

this is a theory, not a fact.
noz - 27 Jun 2005 14:07 GMT
that animals make their own vitamin c ?
Pizza Girl. - 28 Jun 2005 00:21 GMT
all animals but humans and guinea pigs and coincidentally the only animals
that have chloresterol problems.

> that animals make their own vitamin c ?
MMu - 28 Jun 2005 10:13 GMT
> that animals make their own vitamin c ?

no, the interpolation thing.
you just can't compare different species in such a way without taking other
factors into account.
we adopted to having no ability to synthesize ascorbic acid over thousands
of years.. its very unprobable that we will have the same need as animals
that can readily synthesize it.
noz - 28 Jun 2005 16:50 GMT
Vitamin C is needed for oxidative phosphorylation. We still do that, so
we still need vitamin C.
Vitamin C was found to be necessary for cellular respiration in 1928,
the chap got a Nobel for it.
MMu - 29 Jun 2005 08:24 GMT
> Vitamin C is needed for oxidative phosphorylation. We still do that, so
> we still need vitamin C.
> Vitamin C was found to be necessary for cellular respiration in 1928,
> the chap got a Nobel for it.

Where did I say it wasn't needed? I talked about quantities.
noz - 29 Jun 2005 14:19 GMT
That's exactly it, most people don't know they need vitamin C to
breathe, (that's why most respiratory disorders improve with vitamin
C). When one takes this into account , the quantities for health can
worked out.
The concentration of vitamin C needed for adrenal function exceeds
that of the plasma by 100x, as does pituitary need. You simply cannot
supply the organs with enough vitamin C, if you take RDA quantities,
that raise plasma concentrations slightly.
MMu - 29 Jun 2005 16:18 GMT
> That's exactly it, most people don't know they need vitamin C to
> breathe, (that's why most respiratory disorders improve with vitamin
[quoted text clipped - 4 lines]
> supply the organs with enough vitamin C, if you take RDA quantities,
> that raise plasma concentrations slightly.

citation?
noz - 30 Jun 2005 12:08 GMT
1928 ? Szent-Gyorgyi got a nobel prize for discovering vitamin C is
necessary for cellular respiration.
MMu - 01 Jul 2005 09:36 GMT
> 1928 ? Szent-Gyorgyi got a nobel prize for discovering vitamin C is
> necessary for cellular respiration.

...

a citation for THIS or course:

> You simply cannot
> supply the organs with enough vitamin C, if you take RDA quantities,
> that raise plasma concentrations slightly.
noz - 01 Jul 2005 12:58 GMT
This is now in text books .
MMu - 01 Jul 2005 13:28 GMT
> This is now in text books .

Could you be more specific please? Which textbook (title/author(s)/date or
issue)?
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2009 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.