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Medical Forum / General / Nutrition / June 2005L-Tryptophan Available
Doctor's Best is making L-Tryptophan (NOT 5-HTP) and marketing it to humans (not pets). Anyone know how they can do that? I thought it was banned by the FDA because of fears of Eosinophilia-Myalgia Syndrome. http://www.iherb.com/bestltrypto.html http://www.vitasprings.com/l-tryptophan-doctors-best.html http://www.nutritiongeeks.com/best-l-tryptophan-500mg-90/best-l-tryptophan-5 00mg.html > Doctor's Best is making L-Tryptophan (NOT 5-HTP) and marketing it to humans > (not pets). > > Anyone know how they can do that? I thought it was banned by the FDA because > of fears of Eosinophilia-Myalgia Syndrome. Please provide more details on this Doctor's Best product. Did the FDA lift their ban? > Did the FDA lift their ban? Doubt that. The reaction btw. free amino acid and HOCl from activated neutrophils (myelo peroxidase) or from eosinophil peroxidase is rather nasty. Eating free amino acids increase concentration of free amino acids of that kind, and if you are ill etc, the carboxylic group becomes destabilized when the chlorine attacks the amino acid and it is rearranged into formaldehyde. In far bigger amount than you ever will be able to make from decomposition of aspartam (on the other side, phenylalanine and aspartate also do the same, so most possibly, the Ch3-group btw. phenylalanine and aspartic acid is most possibly not responsible for formaldehyde formation, but the amino acids after HOCl attack. Free Radic Biol Med. 2004 Nov 15;37(10):1622-30. Related Articles, Links Erratum in: Free Radic Biol Med.2005 Feb 1;38(3):396. Corrected and republished in: Free Radic Biol Med. 2005 Feb 1;38(3):397-405. Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity. Peskin AV, Midwinter RG, Harwood DT, Winterbourn CC. And some related articles. That why you take lysine with them > > Did the FDA lift their ban? > [quoted text clipped - 27 lines] > > And some related articles. Maybe it is not free-form L-Trytophan and bonded to another amino so it isn't bioavailable. I have tried the pet Trytophan supplements and I can tell you this. There is absolutely no free-form trytophan in it. It is a complete rip-off, a scam and a waste of money. I have taken trytophan and there is none in it. > Doctor's Best is making L-Tryptophan (NOT 5-HTP) and marketing it to humans > (not pets). [quoted text clipped - 4 lines] > http://www.iherb.com/bestltrypto.html > http://www.vitasprings.com/l-tryptophan-doctors-best.html http://www.nutritiongeeks.com/best-l-tryptophan-500mg-90/best-l-tryptophan-5 > 00mg.html > Maybe it is not free-form L-Trytophan and bonded to another amino so it > isn't bioavailable. [quoted text clipped - 17 lines] > http://www.nutritiongeeks.com/best-l-tryptophan-500mg-90/best-l-tryptophan-5 >> 00mg.html How does this one look: http://www.drhoffman.com/page.cfm/529 René Call them at The Store (800)456-9384 and ask if their Trytophan is free form isolated amino acid. Maybe something has openned up in the law lately. This would be nice now Prozac has had it's first 25 years on the market without competition. Order a bottle and try them for a $85 risk. You will know by taking 2000mg within 30 minutes if it is the real stuff. Many would like to know and they will have a huge market if it is good stuff. > > Maybe it is not free-form L-Trytophan and bonded to another amino so it > > isn't bioavailable. [quoted text clipped - 14 lines] > >> http://www.iherb.com/bestltrypto.html > >> http://www.vitasprings.com/l-tryptophan-doctors-best.html http://www.nutritiongeeks.com/best-l-tryptophan-500mg-90/best-l-tryptophan-5 > >> 00mg.html > > > How does this one look: > http://www.drhoffman.com/page.cfm/529 > > Reni Pizza Girl on 5/13/05 9:59 PM at nospam@4.me in 1116039475.02b39ebad18240a43f6d7d1b89934038@teranews wrote: > Call them at The Store > (800)456-9384 [quoted text clipped - 7 lines] > within 30 minutes if it is the real stuff. Many would like to know and they > will have a huge market if it is good stuff. Yes, apparently the ban was lifted in 2001. Not sure why there has not been more available until now - but maybe it has something to do with their still being an import ban, if I read it right. http://vm.cfsan.fda.gov/~dms/ds-tryp1.html |
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