<<snip>>
there was a significant association of serum ferritin and iron overload
with age
<<snip>>

Arch Med Res. 2005 Mar-Apr;36(2):142-7. Related Articles, Links

Evaluation of iron overload in healthy adult residents of Mexico city.

Baptista-Gonzalez H, Rosenfeld-Mann F, Trueba-Gomez R, Mendez-Sanchez
N, Uribe M.

Hematologia Perinatal, Subdireccion de Investigacion Clinica, Instituto
Nacional de Perinatologia, Mexico City, Mexico.

BACKGROUND: We described the effects of age, gender and body mass index
(BMI) on the prevalence of iron overload (IO) in blood donors from
Mexico City. METHODS: A cross-sectional study of clinically healthy
adults was performed. We evaluated serum ferritin (SF) concentration to
allow us to establish groups with normal iron stores (SF >30 mug/L) and
with IO (SF >200 mug/L and >300 mug/L for women and men), in the
following ages groups: 18-29 years, 30-49 years, and 50-64 years,
divided by gender. RESULTS: The study included 1757 subjects.
Prevalence of IO was 12% in men and 4.8% in women, and prevalence
increased in parallel with increasing age (15.6, 25.0 and 29.9% and
3.5, 5.2 and 9.6%, for men and women, respectively). Regression
analysis showed that in men there was a significant association of SF
and IO with age, BMI and recent blood donation (p <0.01). In women, no
differences were seen for BMI and recent blood donation. CONCLUSIONS:
IO is highly prevalent in blood donors residing in Mexico City, more so
in men than in women. Age, gender and BMI had a positive association
with iron stores. This report is the initial contribution towards the
study of IO in the Mexican population.

PMID: 15847947 [PubMed - in process]

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