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Medical Forum / General / Nutrition / December 2004Re: Metformin and weight loss
Yes, it is known to have a small effect to aid weight loss at the beginning that levels off, but in the end weight is lost when fewer calories are eaten over the long term. >I started loosing weight raipdly initially then it stabilised but >I find slowly loosing at 2lbs an year .I am now 158 to 170 3 years back > >Is that normal with Metformin ? > >Kam > >-- >Posted via Mailgate.ORG Server - http://www.Mailgate.ORG > Yes, it is known to have a small effect to aid weight loss at the > beginning that levels off, but in the end weight is lost when fewer > calories are eaten over the long term. Do you consider this a normal phenomena . Does Metformin have any affect on hypertension ? Kam Metformin is known to have an appetite suppressive effect, at least for some folks, although at variable dosages (higher dosages usually eventually result in some appetite suppression, but that dose is varible individual to individual). Weight loss can have a beneficial effect on hypertension, but, AFAIK, metformin does not have any direct effect on hypertension. > Metformin is known to have an appetite suppressive effect, at least for > some folks, although at variable dosages (higher dosages usually [quoted text clipped - 3 lines] > Weight loss can have a beneficial effect on hypertension, but, AFAIK, > metformin does not have any direct effect on hypertension. Thanks , has this any affect on lipid profile ? Kam In most studies, metformin has a beneficial effect on lipid profile, with decreased LDL, improved TG/HDL levels. HDL has been reported to be either non-significantly changed or slightly increased. Yes, only indrectly, weight loss causes often an improvement in all measures of diabetes and related syndromes. Because it decreases blood glucose it removes some cause of the blood vessel stiffening and related disfunctions of high blood pressure. Directly it affects the glucose output of the liver as a contribution to blood glucose levels and by making body cells less resistant to insulin and thus removing glucose more quickly from the blood. It is also thought to have some small positive effect on what is known as glycation, which is an adverse combination of glucose with proteins. > Do you consider this a normal phenomena . Does Metformin >have any affect on hypertension ? [quoted text clipped - 3 lines] >-- >Posted via Mailgate.ORG Server - http://www.Mailgate.ORG |
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