<sniiiip>>

See the header .. ?

Read the header ..

The thread is about .. tocopherol ..

That is vitamin E ..

Take your shite to another .. thread ..

Ann Neurol. 2004 Nov 4 [Epub ahead of print] Related Articles, Links  

 
Vitamin E intake and risk of amyotrophic lateral sclerosis.

Ascherio A, Weisskopf MG, O'reilly EJ, Jacobs EJ, McCullough ML, Calle EE,
Cudkowicz M, Thun MJ.

Department of Nutrition, Harvard School of Public Health.

Oxidative stress may contribute to the pathogenesis of amyotrophic lateral
sclerosis (ALS). We therefore examined prospectively whether individuals who
regularly use supplements of the antioxidant vitamins E and C have a lower risk
of ALS than nonusers. The study population comprised 957,740 individuals 30
years of age or older participating in the American Cancer Society's Cancer
Prevention Study II. Information on vitamin use was collected at time of
recruitment in 1982; participants then were followed up for ALS deaths from
1989 through 1998 via linkage with the National Death Index. During the
follow-up, we documented 525 deaths from ALS. Regular use of vitamin E
supplements was associated with a lower risk of dying of ALS. The age- and
smoking-adjusted relative risk was 0.99 (95% confidence interval [CI],
0.69-1.41) among occasional users, 0.59 (95% CI, 0.36-0.96) in regular users
for less than 10 years, and 0.38 (95% CI, 0.16-0.92) in regular users for 10
years or more as compared with nonusers of vitamin E (p for trend = 0.004). In
contrast, no significant associations were found for use of vitamin C or
multivitamins. These results suggest that vitamin E supplementation could have
a role in ALS prevention. Ann Neurol 2004.

PMID: 15529299 [PubMed - as supplied by publisher]

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