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Medical Forum / General / Nutrition / October 2004

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nutrition and cancer: review of evidence for the anti-cancer diet

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cde - 25 Oct 2004 15:49 GMT
Nutr J. 2004 Oct 20;3(1):19 [Epub ahead of print]

Nutrition and cancer: A review of the evidence for an anti-cancer diet.

Donaldson MS.

It has been estimated that 30-40 percent of all cancers can be prevented by
lifestyle and dietary measures alone. Obesity, nutrient sparse foods such as
concentrated sugars and refined flour products that contribute to impaired
glucose metabolism (which leads to diabetes), low fiber intake,
consumption of
red meat, and imbalance of omega 3 and omega 6 fats all contribute to excess
cancer risk. Intake of flax seed, especially its lignan fraction, and
abundant
portions of fruits and vegetables will lower cancer risk. Allium and
cruciferous
vegetables are especially beneficial, with broccoli sprouts being the
densest
source of sulforophane. Protective elements in a cancer prevention diet
include
selenium, folic acid, vitamin B-12, vitamin D, chlorophyll, and antioxidants
such as the carotenoids (alpha-carotene, beta-carotene, lycopene, lutein,
cryptoxanthin). Ascorbic acid has limited benefits orally, but could be very
beneficial intravenously. Supplementary use of oral digestive enzymes and
probiotics also has merit as anticancer dietary measures. When a diet is
compiled according to the guidelines here it is likely that there would
be at
least a 60-70 percent decrease in breast, colorectal, and prostate
cancers, and
even a 40-50 percent decrease in lung cancer, along with similar
reductions in
cancers at other sites. Such a diet would be conducive to preventing
cancer and
would favor recovery from cancer as well.

PMID: 15496224 [PubMed - as supplied by publisher]

Free downloadable pdf  is here:

http://www.nutritionj.com/content/3/1/19

Summary:

-adqequate but not excessive calories
-10 or more servings of vegetables per day, including crucifer and allium,
juice can partly satisfy the goal
-4 or more servings of fruits per day
-high in fiber
-no refined sugar or flour
-low in total fat but containing necessary EFAs
-no red meat
-balance of omega3 and omega6 fats and preformed DHA
-flax seed as source of phytoestrogens
-supplements: 200 mcg selenium, 1000 mcg methylcobalamin, probiotics,
oral enzymes
-very rich in folic acid
-adequate in vitamin D
-very rich in antioxidants, phytochemicals, and cholorphyll

Donaldson is director of research at Hallelujah Acres Foundation,  which
promotes
a high raw diet.
magnulus - 26 Oct 2004 20:11 GMT
  I bet people could experience much more protection against cancer by
going even further.   Replacing soda pop and bottled water with anti-oxidant
rich drinks would go further to reduce ones cancer risk.  There is evidence
that green and black tea prevent many different kinds of cancer; in some
cases, moderate to high consumption reduces the occurance, for instance, of
stomach or head and neck cancers by more than half, and drinking large
amounts of green tea appears correlated with very low breast cancer risk.
Even fruit juices like grape, orange, black currant, tomato, etc. have
beneficial bioflavanoids, and there are also herbal teas like rooibos or
honeybush that would be caffeine free substitutes to tea.

 All of it adds up; diet, anti-oxidant intake, etc.  In Japan as smoker has
a 4 fold greater risk of contracting lung cancer, in one study, but in the
US the typical smoker faces a 20 fold risk.  That's 5 times greater.  Much
of it can probably be attributed to diet.
cde - 28 Oct 2004 05:39 GMT
>    I bet people could experience much more protection against cancer by
> going even further.    

> There is evidence
> that green and black tea prevent many different kinds of cancer;

Yes, tea polyphenols are discueed in the paper but not the abstract.
Calorie restriction is also discussed.
 
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