Medical Forum / General / General / February 2007
elevated CRP and cortisol
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berni - 30 Jan 2007 00:36 GMT I 'm new to this site and hope you can help connect the dots. After a year of stress, I recently developed a rash (small flesh tone raised areas and sometimes small hives) accompanied by serious itching especially on my arms and back. When my left arm seemed larger than my right, I went to the MD. Sometimes the itching is so bad that bruises develop, especially over fatty tissue. Most significant lab - cortisol 29.1, CRP 3.8, cholesterol 177, HDL 2.3, LDL 88, ESR 8, Rh - 5, ANa negative, CBC, Lytes, BUN, Cr all normal, decadron challenge and 24 hr urine for cortisol and protein came back with low values. CXR neg for thoracic outlet syndrome and mammogram was normal. I will be following up with an Endocrinologist but not til late Feb but this rash is making me nuts. I've changed by diet, less red meat, more veggies, increased my Omega 3. What else can I do til I see the doc and is this rash connected to my labs? What ever insight would be appreciated.
Jason Johnson - 30 Jan 2007 02:03 GMT I 'm new to this site and hope you can help connect the dots. After a year of stress, I recently developed a rash (small flesh tone raised areas and sometimes small hives) accompanied by serious itching especially on my arms and back. When my left arm seemed larger than my right, I went to the MD. Sometimes the itching is so bad that bruises develop, especially over fatty tissue. Most significant lab - cortisol 29.1, CRP 3.8, cholesterol 177, HDL 2.3, LDL 88, ESR 8, Rh - 5, ANa negative, CBC, Lytes, BUN, Cr all normal, decadron challenge and 24 hr urine for cortisol and protein came back with low values. CXR neg for thoracic outlet syndrome and mammogram was normal. I will be following up with an Endocrinologist but not til late Feb but this rash is making me nuts. I've changed by diet, less red meat, more veggies, increased my Omega 3. What else can I do til I see the doc and is this rash connected to my labs? What ever insight would be appreciated.
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Hello, I checked my 1000 page medical book and found out that the following things can cause hives and itching problems: kidney disorder liver disorder thyroid disorder allergic reaction reactions to medication(s) cancer (esp. leukemia) Food dyes and and preservatives
Check your creatinine level--if it's above the reference range, it could indicate kidney problems. Check your ALT and AST levels--If those levels are above the reference range, it could indicate liver related problems. You may want to read this book since it will help you understand Blood test results: NORMAL BLOOD TEST SCORES AREN'T GOOD ENOUGH by Ellen Cullen R.N.
Jason ~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Jeff - 30 Jan 2007 12:17 GMT > I 'm new to this site and hope you can help connect the dots. After a year > of [quoted text clipped - 21 lines] > Hello, > I checked my 1000 page medical book and found out that the following Which 1000-page medical book?
> things can cause hives and itching problems: > kidney disorder [quoted text clipped - 15 lines] > Jason > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~ berni - 30 Jan 2007 23:42 GMT > I 'm new to this site and hope you can help connect the dots. After a year of > stress, I recently developed a rash (small flesh tone raised areas and [quoted text clipped - 33 lines] >Jason >~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Thanks for the reference book. Creatinine, ALT and AST were normal thanks, Berni
Jason Johnson - 31 Jan 2007 01:35 GMT Jason Johnson wrote:
> I 'm new to this site and hope you can help connect the dots. After a year of > stress, I recently developed a rash (small flesh tone raised areas and [quoted text clipped - 33 lines] >Jason >~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Thanks for the reference book. Creatinine, ALT and AST were normal thanks, Berni
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Berni, There are various types of autoimmune disorders so you should consider asking your doctor to do ANA Tests (Autoimmune Assays) to rule in or rule out an autoimmune disorder as a cause of your problem. You may have developed an allergic reaction to certain foods or products. For example, wash all of your clothing with Woolite or any other product that does NOT contain bleach or phosphates. Do not eat shell fish. Do a google search for the term "Allergy Diet". Don't eat processed or seasoned meat such as cold cuts. I was pleased to learn that your creatinine, ALT and AST were normal. That is great news. Also google the term "hives". You should also make a list of the questions that want to ask the endocrinologist. I tend to forget questions that I want to ask doctors if I don't have them written down.
Jason ~~~~~~~~~~~~~~~~~~~~~~
Jeff - 30 Jan 2007 14:38 GMT >I 'm new to this site and hope you can help connect the dots. After a year >of [quoted text clipped - 16 lines] > rash > connected to my labs? What ever insight would be appreciated. We know next to nonething about you. Not even whether you are male or female (ok, themammogram gives a clue here) and how old you are. Or how heavy you are.
The raised cortisol indicates some stress and the CRP indicates some inflammation.The low HDL and low HDL:LDL ratio is worrisome for your heart. The Rh might be rheumatoid factor or something, but I don't know. ANA negative is normal. A positive ANA indicates autoimmune disease, a negative one means autoimmune disease is less likely, but doesn't rule it out.
Why don't you ask the doctor who gave you the lab tests?
Jeff
Jason Johnson - 30 Jan 2007 20:23 GMT "berni" <u31335@uwe> wrote in message news:6d080eb792a52@uwe...
>I 'm new to this site and hope you can help connect the dots. After a year >of [quoted text clipped - 16 lines] > rash > connected to my labs? What ever insight would be appreciated. We know next to nonething about you. Not even whether you are male or female (ok, themammogram gives a clue here) and how old you are. Or how heavy you are. The raised cortisol indicates some stress and the CRP indicates some inflammation.The low HDL and low HDL:LDL ratio is worrisome for your heart. The Rh might be rheumatoid factor or something, but I don't know. ANA negative is normal. A positive ANA indicates autoimmune disease, a negative one means autoimmune disease is less likely, but doesn't rule it out. Why don't you ask the doctor who gave you the lab tests? Jeff
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Jeff, Great post. My neighbor has Lupus which is a autoimmune disease and she has major itching problems. I also found out that Aspartame can cause itching problems and that MSG (a food additive) can cause the release of adrenal stress hormones. Can diabetes also cause itching problems? Jason ~~~~~~~~~~~~~~~~~~~~~~~~~
vad123@gmail.com - 02 Feb 2007 02:46 GMT > "berni" <u31335@uwe> wrote in messagenews:6d080eb792a52@uwe... > [quoted text clipped - 43 lines] > Jason > ~~~~~~~~~~~~~~~~~~~~~~~~~ Diabetes can cause skin infections both fungal and bacterial which can in turn cause itching. Also diabetic neuropathy might cause itching but more classically numbing and loss of sensation or a burning sensation - but this is usually "late in the game".
berni - 30 Jan 2007 23:40 GMT >>I 'm new to this site and hope you can help connect the dots. After a year >>of [quoted text clipped - 10 lines] >The Rh might be rheumatoid factor or something, but I don't know. ANA >negative is normal. A positive ANA indicates autoimmune disease, a negative
>one means autoimmune disease is less likely, but doesn't rule it out. > >Why don't you ask the doctor who gave you the lab tests? > >Jeff Sorry folks, here's some more info: female 40+++ overweight clarification on labs - HDL 76, LDL -88, ratio 2.3 (thought these values were good) Rheumatoid factor - 5, this is a good thing My MD was unsure about the rash and requested I see the endocrinologist but I can't see him til 2/27 I was worried about lupus but according to my doc, i don't meet the criteria I am concerned about metabolic syndrome and a stress response let me know if this info helps
Jeff - 31 Jan 2007 13:03 GMT >>>I 'm new to this site and hope you can help connect the dots. After a >>>year [quoted text clipped - 36 lines] > I am concerned about metabolic syndrome and a stress response > let me know if this info helps I guess diabetes can cause a rash like that. You don't have diabetes (your blood glucose is apparently normal - you didn't mention it being high). Your cholesterol is ok (you confused me before when you said your HDL was 2.3 - that was the ratio). So you don't have metabolic syndrome.
Although you don't have metabolic syndrome, losing weight would be useful. Get more excercise and learn to eat healthy. Prevention is better than a cure, especially with diabetes, because with diabetes, there is control, but no cure.
For lupus, the rash is usually on the face, but it can be elsewhere. Even though you don't meet the criteria by the lab tests, you could still have lupus or autoimmune problem. This doesn't sound like an autoimmune problem, though. And, of course, you have a rash. I think I would want to see a dermatologist and ask about seeing a rhumatologist.
Jeff
berni - 03 Feb 2007 21:25 GMT >>>>I 'm new to this site and hope you can help connect the dots. After a >>>>year [quoted text clipped - 19 lines] > >Jeff Thanks folks for your suggestions. I planned on calling the dermatologist , hopefully I can see him before the end of the month. I have an appt. with my medical next week and I wanted to review with him about the possibility of lupus as well. The challenge is trying to get in to see any of these docs. I'll update when possible. Thanks, Berni
vad123@gmail.com - 02 Feb 2007 02:44 GMT > I 'm new to this site and hope you can help connect the dots. After a year of > stress, I recently developed a rash (small flesh tone raised areas and [quoted text clipped - 9 lines] > increased my Omega 3. What else can I do til I see the doc and is this rash > connected to my labs? What ever insight would be appreciated. I would think you might need a skin biopsy and a visit to the dermatologist if the skin rash doesnt go away. I dont think your labs help all that much. I think you should try to see a dermatologist - he might help you out with either some topical or oral steroid if necessary.
Btw a common cause of hives - if thats what you have - is environmental so see if anitihistamines (claritin, benadryl, etc.) work 4 u.
-good luck
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