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Medical Forum / General / General / February 2007

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elevated CRP and cortisol

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berni - 30 Jan 2007 00:36 GMT
I 'm new to this site and hope you can help connect the dots. After a year of
stress, I recently developed a rash (small flesh tone raised areas and
sometimes small hives) accompanied by serious itching especially on my arms
and back.  When my left arm seemed larger than my right, I went to the MD.
Sometimes the itching is so bad that bruises develop, especially over fatty
tissue.  Most significant lab - cortisol 29.1, CRP 3.8,  cholesterol 177, HDL
2.3, LDL 88, ESR 8, Rh - 5, ANa negative, CBC, Lytes, BUN, Cr all normal,
decadron challenge and 24 hr urine for cortisol and protein came back with
low values. CXR neg for thoracic outlet syndrome and mammogram was normal. I
will be following up with an Endocrinologist but not til late Feb but this
rash is making me nuts.  I've changed by diet, less red meat, more veggies,
increased my Omega 3.  What else can I do til I see the doc and is this rash
connected to my labs?  What ever insight would be appreciated.
Jason Johnson - 30 Jan 2007 02:03 GMT
I 'm new to this site and hope you can help connect the dots. After a year of
stress, I recently developed a rash (small flesh tone raised areas and
sometimes small hives) accompanied by serious itching especially on my arms
and back.  When my left arm seemed larger than my right, I went to the MD.
Sometimes the itching is so bad that bruises develop, especially over fatty
tissue.  Most significant lab - cortisol 29.1, CRP 3.8,  cholesterol 177, HDL
2.3, LDL 88, ESR 8, Rh - 5, ANa negative, CBC, Lytes, BUN, Cr all normal,
decadron challenge and 24 hr urine for cortisol and protein came back with
low values. CXR neg for thoracic outlet syndrome and mammogram was normal. I
will be following up with an Endocrinologist but not til late Feb but this
rash is making me nuts.  I've changed by diet, less red meat, more veggies,
increased my Omega 3.  What else can I do til I see the doc and is this rash
connected to my labs?  What ever insight would be appreciated.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Hello,
I checked my 1000 page medical book and found out that the following
things can cause hives and itching problems:
kidney disorder
liver disorder
thyroid disorder
allergic reaction
reactions to medication(s)
cancer (esp. leukemia)
Food dyes and and preservatives

Check your creatinine level--if it's above the reference range, it could
indicate kidney problems.
Check your ALT and AST levels--If those levels are above the reference
range, it could indicate liver related problems.
You may want to read this book since it will help you understand Blood
test results:
NORMAL BLOOD TEST SCORES AREN'T GOOD ENOUGH by Ellen Cullen R.N.

Jason
~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Jeff - 30 Jan 2007 12:17 GMT
> I 'm new to this site and hope you can help connect the dots. After a year
> of
[quoted text clipped - 21 lines]
> Hello,
> I checked my 1000 page medical book and found out that the following

Which 1000-page medical book?

> things can cause hives and itching problems:
> kidney disorder
[quoted text clipped - 15 lines]
> Jason
> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~
berni - 30 Jan 2007 23:42 GMT
> I 'm new to this site and hope you can help connect the dots. After a year of
> stress, I recently developed a rash (small flesh tone raised areas and
[quoted text clipped - 33 lines]
>Jason
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Thanks for the reference book.  Creatinine, ALT and AST were normal
thanks,
Berni
Jason Johnson - 31 Jan 2007 01:35 GMT
Jason Johnson wrote:
> I 'm new to this site and hope you can help connect the dots. After a year of
> stress, I recently developed a rash (small flesh tone raised areas and
[quoted text clipped - 33 lines]
>Jason
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Thanks for the reference book.  Creatinine, ALT and AST were normal
thanks,
Berni

~~~~~~~~~~~~~~~~~~

Berni,
There are various types of autoimmune disorders so you should consider
asking your doctor to do ANA Tests (Autoimmune Assays) to rule in or rule
out an autoimmune disorder as a cause of your problem. You may have
developed
an allergic reaction to certain foods or products. For example, wash all of
your clothing with Woolite or any other product that does NOT contain
bleach or phosphates. Do not eat shell fish. Do a google search for the
term "Allergy Diet". Don't eat processed or seasoned meat such as cold
cuts. I was pleased to learn that your creatinine, ALT and AST were normal.
That is great news. Also google the term "hives". You should also make a
list of the questions that want to ask the endocrinologist. I tend to
forget questions that I want to ask doctors if I don't have them written
down.

Jason
~~~~~~~~~~~~~~~~~~~~~~
Jeff - 30 Jan 2007 14:38 GMT
>I 'm new to this site and hope you can help connect the dots. After a year
>of
[quoted text clipped - 16 lines]
> rash
> connected to my labs?  What ever insight would be appreciated.

We know next to nonething about you. Not even whether you are male or female
(ok, themammogram gives a clue here) and how old you are. Or how heavy you
are.

The raised cortisol indicates some stress and the CRP indicates some
inflammation.The low HDL and low HDL:LDL ratio is worrisome for your heart.
The Rh might be rheumatoid factor or something, but I don't know. ANA
negative is normal. A positive ANA indicates autoimmune disease, a negative
one means autoimmune disease is less likely, but doesn't rule it out.

Why don't you ask the doctor who gave you the lab tests?

Jeff
Jason Johnson - 30 Jan 2007 20:23 GMT
"berni" <u31335@uwe> wrote in message news:6d080eb792a52@uwe...
>I 'm new to this site and hope you can help connect the dots. After a year
>of
[quoted text clipped - 16 lines]
> rash
> connected to my labs?  What ever insight would be appreciated.

We know next to nonething about you. Not even whether you are male or female
(ok, themammogram gives a clue here) and how old you are. Or how heavy you
are.

The raised cortisol indicates some stress and the CRP indicates some
inflammation.The low HDL and low HDL:LDL ratio is worrisome for your heart.
The Rh might be rheumatoid factor or something, but I don't know. ANA
negative is normal. A positive ANA indicates autoimmune disease, a negative
one means autoimmune disease is less likely, but doesn't rule it out.

Why don't you ask the doctor who gave you the lab tests?

Jeff

~~~~~~~~~~~~~~~~~~

Jeff,
Great post. My neighbor has Lupus which is a autoimmune disease and she
has major itching problems. I also found out that Aspartame can cause
itching problems and that MSG (a food additive) can cause the release of
adrenal stress
hormones. Can diabetes also cause itching problems?
Jason
~~~~~~~~~~~~~~~~~~~~~~~~~
vad123@gmail.com - 02 Feb 2007 02:46 GMT
>  "berni" <u31335@uwe> wrote in messagenews:6d080eb792a52@uwe...
>
[quoted text clipped - 43 lines]
> Jason
> ~~~~~~~~~~~~~~~~~~~~~~~~~

Diabetes can cause skin infections both fungal and bacterial which can
in turn cause itching. Also diabetic neuropathy might cause itching
but more classically numbing and loss of sensation or a burning
sensation - but this is usually "late in the game".
berni - 30 Jan 2007 23:40 GMT
>>I 'm new to this site and hope you can help connect the dots. After a year
>>of
[quoted text clipped - 10 lines]
>The Rh might be rheumatoid factor or something, but I don't know. ANA
>negative is normal. A positive ANA indicates autoimmune disease, a negative

>one means autoimmune disease is less likely, but doesn't rule it out.
>
>Why don't you ask the doctor who gave you the lab tests?
>
>Jeff

Sorry folks, here's some more info:
female
40+++
overweight
clarification on labs - HDL 76, LDL -88, ratio 2.3 (thought these values were
good)
Rheumatoid factor - 5, this is a good thing
My MD was unsure about the rash and requested I see the endocrinologist but I
can't see him til 2/27
I was worried about lupus but according to my doc, i don't meet the criteria
I am concerned about metabolic syndrome and a stress response
let me know if this info helps
Jeff - 31 Jan 2007 13:03 GMT
>>>I 'm new to this site and hope you can help connect the dots. After a
>>>year
[quoted text clipped - 36 lines]
> I am concerned about metabolic syndrome and a stress response
> let me know if this info helps

I guess diabetes can cause a rash like that. You don't have diabetes (your
blood glucose is apparently normal - you didn't mention it being high). Your
cholesterol is ok (you confused me before when you said your HDL was 2.3 -
that was the ratio). So you don't have metabolic syndrome.

Although you don't have metabolic syndrome, losing weight would be useful.
Get more excercise and learn to eat healthy. Prevention is better than a
cure, especially with diabetes, because with diabetes, there is control, but
no cure.

For lupus, the rash is usually on the face, but it can be elsewhere. Even
though you don't meet the criteria by the lab tests, you could still have
lupus or autoimmune problem. This doesn't sound like an autoimmune problem,
though. And, of course, you have a rash. I think I would want to see a
dermatologist and ask about seeing a rhumatologist.

Jeff
berni - 03 Feb 2007 21:25 GMT
>>>>I 'm new to this site and hope you can help connect the dots. After a
>>>>year
[quoted text clipped - 19 lines]
>
>Jeff

Thanks folks for your suggestions. I planned on calling the dermatologist ,
hopefully I can see him before the end of the month.  I have an appt. with my
medical next week and I wanted to review with him about the possibility of
lupus as well.  The challenge is trying to get in to see any of these docs.
I'll update when possible.
Thanks,
Berni
vad123@gmail.com - 02 Feb 2007 02:44 GMT
> I 'm new to this site and hope you can help connect the dots. After a year of
> stress, I recently developed a rash (small flesh tone raised areas and
[quoted text clipped - 9 lines]
> increased my Omega 3.  What else can I do til I see the doc and is this rash
> connected to my labs?  What ever insight would be appreciated.

I would think you might need a skin biopsy and a visit to the
dermatologist if the skin rash doesnt go away. I dont think your labs
help all that much.
I think you should try to see a dermatologist - he might help you out
with either some topical or oral steroid if necessary.

Btw a common cause of hives - if thats what you have - is
environmental so see if anitihistamines (claritin, benadryl, etc.)
work 4 u.

-good luck
 
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