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Medical Forum / General / General / December 2006glucosamine?
I've been sufering shoulder pain, bursitis or tendonitis or whatever. Glucosamine is all the rage for joint pain lately. Is there any clinical data to back up these claims? If so, what is the recommended dosage? More critically, what would constitute an overdose? There's also MSM and chondroitin... -- Rich The only proper controlled research done did not support any benefit, hopefully others will be done to see if those results will persist. The conditions you mention aren't usually associated with use of this substance, it sounds more like frozen sholder instead. This is common in diabetics, are you one by any chance and have you had a blood glucose test recently? >I've been sufering shoulder pain, bursitis or tendonitis or whatever. >Glucosamine is all the rage for joint pain lately. Is there any [quoted text clipped - 6 lines] >-- >Rich >The only proper controlled research done did not support any benefit, That's a complete misrepresentation of those data. The combination of glucosamine/chondroitin among those with severe osteoarthritis of the knee had a significant effect and was overall much safer than the COX2 alternative. Other data have indeed supported the use of this very safe intervention. I'd say it is worth a try based on the data--beats sh.t out of getting a heart attack from some toxic, overpriced and overhyped drug, doesn't it? George M. Carter A combination of glucosamine, chondroitin and MSN has been proven to help with arthritis symptoms in animals. Being natural products they don't have a toxic dose. Common sense dosing is best. crvc56@msn.com wrote in part: >Being natural products they >don't have a toxic dose. Huh? Even water has an LD50 (toxic dose). -- Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu > A combination of glucosamine, chondroitin and MSN has been proven to >help with arthritis symptoms in animals. Being natural products they >don't have a toxic dose. Common sense dosing is best. The first statement may be true but is unsupported with a citation to the literature. Also "proven" is inappropriate. Evidence for safety and efficacy is all one can say from ANY clinical trial. Drug, supplement, reiki or diet. Natural products doesn't mean anything. HIV and tsunamis are natural. Vitamin B12 I think would be VERY hard to find a toxic dose. Artemisia annua could very quickly result in toxicity. Arsenic or lead are quite natural....etc. Thus, "common sense" does not apply. Intelligent application of knowledge that is available is wiser use. People's lives and health depend on such wisdom. Drug companies and many supplement salespeople do not give a rat's a.s about the customer's health as long as they can cram more drugs down people's throats at outrageous cost (and as long as they can pay the rapacious prices). The healthcare system and science have been destroyed by greed and ignorance in the United States. And the pharmaceutical, diagnostic and device manufacturing industries are the lead culprits, with their venal servants in Washington. George M. Carter >Being natural products they >don't have a toxic dose. Here's a kilogram of ricin. Eat it. All natural.  SignaturePeter Bowditch aa #2243 The Millenium Project http://www.ratbags.com/rsoles Australian Council Against Health Fraud http://www.acahf.org.au Australian Skeptics http://www.skeptics.com.au To email me use my first name only at ratbags.com >>Being natural products they >>don't have a toxic dose. > > Here's a kilogram of ricin. Eat it. All natural. Better than that... castor beans! >>>Being natural products they >>>don't have a toxic dose. >> >> Here's a kilogram of ricin. Eat it. All natural. > >Better than that... castor beans! I was saving him the trouble of eating enough beans to get a kilo of ricin. Doing it my way he doesn't have to waste energy biting down on the seeds. All he has to do is take a good sniff of the freeze-dried powder and then wash the rest down with an acceptable but unobtrusive chardonnay. I would have suggested botulin but it's a thousand times more toxic than ricin while being only a hundred times more natural. SignaturePeter Bowditch aa #2243 The Millenium Project http://www.ratbags.com/rsoles Australian Council Against Health Fraud http://www.acahf.org.au Australian Skeptics http://www.skeptics.com.au To email me use my first name only at ratbags.com >>>>Being natural products they >>>>don't have a toxic dose. [quoted text clipped - 8 lines] > powder and then wash the rest down with an acceptable but unobtrusive > chardonnay. Actually, castor bean is so poisonous it only takes a couple of beans. You don't need a whole kilogram. > I would have suggested botulin but it's a thousand times more toxic > than ricin while being only a hundred times more natural. >I've been sufering shoulder pain, bursitis or tendonitis or whatever. >Glucosamine is all the rage for joint pain lately. Is there any >clinical data to back up these claims? If so, what is the >recommended dosage? More critically, what would constitute >an overdose? Get a diagnosis first. You may be able to cure or alleviate your problem and prevent progression or recurrence with a few sessions of physiotherapy. >I've been sufering shoulder pain, bursitis or tendonitis or whatever. >Glucosamine is all the rage for joint pain lately. Is there any [quoted text clipped - 3 lines] > >There's also MSM and chondroitin... Unless your problem is arthritis, rather than, say, bursitis or some other type of inflammation, I don't know that glucosamine is apt to help much. -- David Wright :: alphabeta at prodigy.net These are my opinions only, but they're almost always correct. "If George Bush were my dad, I'd be drunk in public so often that James Baker would have me killed." -- Bill Maher on the Bush twins > I've been sufering shoulder pain, bursitis or tendonitis or whatever. > Glucosamine is all the rage for joint pain lately. > There's also MSM and chondroitin... Joint formulas are not indicated for tendonitis or bursitis relief which is inflamation of the surrounding tissues of a joint - usually from overuse and or injury. Altho a side benefit as reducing inflammation, you might need to do some reading up on these supplements to know what they are supposed to do and then go from there if it sounds like it might be of benefit to you. Just a few links to get you started: Glucosamine - relief of stiffness and pain (acts to lubricate and 'fill in' the cartilege so its all smoother) http://www.supplementwatch.com/suplib/supplement.asp?DocId=1140 Chondroitin - helps cartilage repair itself : http://www.supplementwatch.com/suplib/supplement.asp?DocId=1080 MSM - a sulfer source necessary for connective tissues/collagen within cartilage http://www.supplementwatch.com/suplib/supplement.asp?DocId=1198 joanne
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