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Medical Forum / General / General / September 2006Fever vs Heat inflammation
Just curious: What is the difference between fever and the heat that is one of the characteristic signs of inflammation? Henry > Just curious: What is the difference between fever and the heat that is > one of the characteristic signs of inflammation? > > Henry Fever is systemic through out the body and inflammation can be a localized event. Localized inflammation may generate systemic cytokines and cause fever. It depends on the type of cytokines and the extent of release of such cytokines that results in detectable fever. > > Just curious: What is the difference between fever and the heat that is > > one of the characteristic signs of inflammation? [quoted text clipped - 6 lines] > It depends on the type of cytokines and the extent of release of such > cytokines that results in detectable fever. I see. But would the origins of heat be different? That is, I know the heat from inflammation results from dilation of arterioles and increased permeability of capillaries, but would they be the same for fever? >> > Just curious: What is the difference between fever and the heat that is >> > one of the characteristic signs of inflammation? [quoted text clipped - 11 lines] >increased permeability of capillaries, but would they be the same for >fever? An inflamed area has an increased blood supply, so it is warmer than adjacent areas if it's near the surface, because its temperature will be closer to the body's core temperature. In fever the body's "thermostat" in the brain is "set higher", so mechanisms that maintain body temperature in the set range are activated to increase that range to the new setting. People often experience chills at the onset of fever, since shivering is one way of increasing body temperature. Metabolic rate also increases overall. IIRC, one Celsius degree of fever increases metabolic rate by about 7%. (I'm surprised that nobody has exploited artificially induced fever as a weight-loss scam -- increasing metabolic rate by 15-20% and being too miserable to have an appetite should take at least a few kilograms a week off of most people. ;-) ) > >> > Just curious: What is the difference between fever and the heat that is > >> > one of the characteristic signs of inflammation? [quoted text clipped - 22 lines] > body temperature. Metabolic rate also increases overall. IIRC, one > Celsius degree of fever increases metabolic rate by about 7%. Thanks for that, I get it now. Explains why when I get fevers, my body temperature goes up, but I still need a blanket around me. > (I'm surprised that nobody has exploited artificially induced fever > as a weight-loss scam -- increasing metabolic rate by 15-20% and > being too miserable to have an appetite should take at least a few > kilograms a week off of most people. ;-) ) > >> > Just curious: What is the difference between fever and the heat that is > >> > one of the characteristic signs of inflammation? [quoted text clipped - 27 lines] > being too miserable to have an appetite should take at least a few > kilograms a week off of most people. ;-) ) Good reply. I have few questions in this regard; Is it necessary that local warming means inflammation in that area? How people with local warmed areas, feel heat and cold or experiance flushing or chills? Whether local warming is related to vasodilation in that area? Whether fever is related to vasoconstriction? |
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